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New research found that youth who become increasingly addicted to social media, mobile phones or video games are at greater risk of suicidal thoughts, suicide attempts and emotional or behavioral issues. The study, published in JAMA, was led by researchers at Weill Cornell Medicine, Columbia University and University of California, Berkeley.

Unlike previous studies that focused on total screen time at one point in a child’s life, this study looked at how young people’s patterns of compulsive or “addictive” use changed over time. These patterns included feeling unable to stop using a device, experiencing distress when not using it or using it to escape from problems. In contrast, simply spending more time on screens at 10 years old wasn’t associated with worse suicide-related and mental health outcomes.

“For parents and educators, the discussion around mobile phones and social media has focused on limiting or banning use, but our results indicate more complex factors are involved,” said first author Dr. Yunyu Xiao, assistant professor of population health sciences at Weill Cornell Medicine. “Clinical trials have shown that limiting cell phone use, for instance during school hours, was not effective in reducing the risk of suicidal behavior or improving other aspects of mental health.”

This study could signal a paradigm shift in how the impact of screen time on youth mental health is addressed. “Testing interventions that work against other types of addiction may be one way to approach this type of social media and mobile phone use,” Dr. Xiao said.

Dr. John Mann, the Paul Janssen Professor of Translational Neuroscience in Psychiatry and Radiology at Columbia University and the New York State Psychiatric Institute, is senior author on this study.

Quantity Versus Quality

Over four years, the researchers tracked nearly 4,300 youths aged nine to ten when they first started the study. Participants identified themselves as Asian, Black, Hispanic, white or multiracial. Using machine learning and data from participant interviews, the researchers characterized three addictive use trajectories for social media and mobile phone usage and two for addictive use with video games. When graphed, these trajectories depicted relative levels of addictive behaviors.

By age 14, almost one in three participants had a high addictive use trajectory for social media and one in four for mobile phones. More than 40 percent of the youths had a high addictive use trajectory for video games. These adolescents were significantly more likely to report suicidal thoughts or behaviors, as well as symptoms of anxiety, depression, aggression or rule-breaking.

The researchers also found that each type of digital activity showed unique patterns of association with suicide-related behaviors and mental health symptoms. For social media and mobile phones, the high and increasing addictive use trajectories were associated with a two to three times greater risk of suicidal behaviors and suicidal ideation compared with the low addictive use trajectory. The higher use trajectories were also associated with either internalizing symptoms such as anxiousness and depression, or externalizing symptoms, including aggressiveness or inattentiveness.

“Parents may want to pay more attention to how their kids are using their digital devices and consider having them evaluated for signs of addictive use, said co-first author Dr. Yuan Meng, postdoctoral associate in population health sciences at Weill Cornell. “If an addiction is identified, limiting use of mobile phones and social media for part of the day, may potentially reinforce addictive behaviors, so seeking professional advice is essential.”

Paradigm Shift

This study demonstrated that the total amount of time spent on social media, mobile phones and video games was not associated with future suicide-related or mental health outcomes. What mattered most was how youth were engaging with screens-especially whether their use showed signs of compulsion, distress or loss of control.

The findings suggest repeated assessment of social media and mobile phones in children entering adolescence for addictive use patterns could be valuable. “Children who initially display low or moderate trajectories are not typically considered at-risk, but follow-up can detect concerning trends such as development of more severe addictive use over time,” Dr. Xiao said.

Though the study does not prove addictive screen use causes mental health problems-higher addiction use trajectories are linked to roughly double the risk of suicidal behavior in the near future of these teens. “This calls for further study and evaluation of approaches that have worked for other addictions in children and adolescents for this issue,” Dr. Mann said.

Next, Dr. Xiao and her colleagues plan to extract profiles of children who comprise different trajectories with their demographic and socioeconomic information. The researchers are also developing interventions to address addictive use behaviors at their onset to reduce the likelihood of suicidal behaviors.

Reference:

Xiao Y, Meng Y, Brown TT, Keyes KM, Mann JJ. Addictive Screen Use Trajectories and Suicidal Behaviors, Suicidal Ideation, and Mental Health in US Youths. JAMA. Published online June 18, 2025. doi:10.1001/jama.2025.7829

The FDA has approved the Felix™ NeuroAI™ Wristband, a wearable AI-driven neurostimulation device, for treating upper limb functional limitations in adults with essential tremor. The cloud-based system delivers personalized therapy, continuously adjusting stimulation throughout the day based on the patient’s needs.

“The Felix wristband represents a significant step forward in noninvasive, personalized treatment options for essential tremor,” said Rajesh Pahwa, M.D., Laverne and Joyce Rider Professor of Neurology at the University of Kansas School of Medicine, Director of the Movement Disorder Program at The University of Kansas Health System. “For many patients, current treatment options fall short-pharmaceutical treatments are helpful for less than 50% of the patients, and deep brain stimulation and focused ultrasound, while effective, require surgical intervention. This new AI wearable wristband backed by clinical evidence is an effective treatment option in patients with essential tremor.”

Essential tremor is the most common type of tremor disorder, affecting approximately 7 million people in the U.S., and is about seven times more common than Parkinson’s disease. It causes involuntary, rhythmic shaking, most often in the hands, which can make simple and everyday activities like drinking from a glass or tying shoelaces difficult. Traditional treatment options are limited, with oral medications providing inconsistent relief and often accompanied by undesirable side effects.4 Surgical interventions such as deep brain stimulation (DBS), while effective, require invasive procedures, carry surgical risks, and may not be suitable or desirable for all patients, particularly older adults or those with coexisting health conditions.

Unlike surgical or pharmacologic interventions, Felix is a noninvasive, wearable device that effortlessly connects to Fasikl’s cloud-based AI platform, enabling continuous brain-AI co-adaptation and personalized therapy. Worn on the wrist, it uses the cloud to dynamically adjust stimulation, offering all-day symptom relief while seamlessly fitting into the wearer’s lifestyle.

The FDA clearance of Felix is supported by compelling data from the TRANQUIL study, a randomized, double-blind, sham-controlled trial that met its primary endpoint. Results showed that the Felix wristband significantly reduced tremors and displayed statistically and clinically significant improvement in the users’ ability to perform daily activities compared to those using the sham device (“placebo effect”). Efficacy was consistent across demographics, with no serious device-related adverse events reported. Results were presented as Late-breaking Science at the American Academy of Neurology annual meeting in April 2025, reinforcing Felix’s safety and potential as a first-of-its-kind, noninvasive, AI-powered treatment.

“FDA clearance of Felix marks a defining moment for Fasikl and the millions of people living with essential tremor who have long been underserved by existing therapies,” said Zhi Yang, Ph.D., CEO of Fasikl. “This breakthrough in noninvasive, intelligent, and personalized neuromodulation marks the emergence of AI therapeutics in disease treatment. It offers a new option that is potentially more effective, safer, and more scalable. Our next step is to execute the commercialization plan to support Felix’s initial product launch.”

The Felix NeuroAI Wristband will be available by prescription through healthcare providers in select U.S. regions starting in 2025, with nationwide availability expected in 2026.

China: A recent study published in Frontiers in Medicine highlights a significant relationship between the severity of lower urinary tract symptoms/benign prostatic hyperplasia (LUTS/BPH) and lifestyle choices, the presence of multiple chronic conditions, and mental health status among older Chinese men. Conducted by Yifan Wu and colleagues from the Department of Urology, Jiangnan University Medical Center, Wuxi, China, the research emphasizes the importance of a holistic approach to managing LUTS/BPH.