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According to recent reports from the World Health Organization, iodine intake, crucial for thyroid function, is sufficient or even excessive in numerous countries due to iodization policies. While this may seem beneficial for addressing iodine deficiency, concerns have emerged regarding the potential adverse effects of excess iodine on communities. A groundbreaking study has delved into the intricate relationship between iodine exposure and testosterone levels in men, shedding light on a previously unexplored aspect of reproductive health. The study revealed that low urinary iodine concentration is an independent factor causing increased testosterone levels and hence men should be cautioned while taking iodine supplementation. 

The study results were published in the journal JAMA Network Open. 

Also Read: Can Iodophor-Impregnated Drapes be used in patients with Iodine-Related Allergies?

The study, drawing on data from the National Health and Nutrition Examination Survey (NHANES), a comprehensive survey of the US population, aimed to investigate the association between urinary iodine concentration (UIC) and testosterone levels. The rationale behind this inquiry lies in the identification of iodine transporters in extrathyroidal tissues, including the testis, raising questions about the impact of iodine on male reproductive hormones.

In a cross-sectional analysis encompassing five NHANES cycles spanning from 1999 to 2002 and 2011 to 2016, the study focused on 11,433 male participants with available data on total testosterone (TT). After excluding individuals with missing UIC data and those below 18 years old, 2,934 men formed the basis for the investigation. Adhering to the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) reporting guidelines, the levels of total testosterone (TT) and urinary iodine concentration (UIC) were examined through inductively coupled plasma dynamic reaction cell mass spectroscopy and isotope dilution high-performance liquid chromatography–tandem mass spectrometry, respectively. Free testosterone (cFT) was calculated using the Vermeulen formula.

To assess distinctions among UIC groups, the Wilcoxon rank-sum test, or χ2 test, was employed. Covariates selected for univariate regressions were based on pre-existing pathophysiological knowledge. Subsequently, multivariable linear regression analysis, applied to log-transformed values, gauged the independent association between continuous UIC and TT levels.

Results:

• The findings revealed a noteworthy correlation between UIC and testosterone levels.
• Men with low UIC exhibited higher levels of both total testosterone and calculated free testosterone (cFT) compared to those with normal and high UIC.
• Additionally, the low-UIC group displayed a more favorable metabolic and glycolipid profile, including a lower body mass index.
• Through multivariable linear regression analysis, adjusting for various factors such as age and features of metabolic syndrome, the negative association between UIC and TT persisted.
• This intriguing evidence challenges previous assumptions about the effects of iodine on male reproductive hormones.

Thus, the research shows a correlation between lower urinary iodine concentration (UIC) and higher testosterone levels, irrespective of factors affecting androgen status. The study suggests caution in excessive iodine supplementation due to potential effects on testicular steroidogenesis.

Also Read: Guidance on patient preparation and radiation protection for patients undergoing radioiodine treatment for thyroid cancer

While the study acknowledges its limitations, including the cross-sectional design that does not establish cause-effect relationships, the implications are significant. The observed link between lower UIC and higher testosterone levels prompts further investigation into the causal directionality of this association. The study also underscores the need for a nuanced understanding of iodine’s impact on reproductive health, moving beyond its well-established role in thyroid function.

Further reading: Barbonetti A, Castellini C, Di Giulio F, et al. Iodine Intake and Testosterone. JAMA Netw Open. 2023;6(12):e2348573. doi:10.1001/jamanetworkopen.2023.48573

Bijnor: A tragic incident unfolded in Dariyapur village of Bijnor district, where a 25-year-old man allegedly committed suicide by hanging himself from a tree after he was issued a Rs 2 crore defamation notice from a private hospital.  

The notice was issued after he had accused Pooja Nursing Home of withholding information about his father’s death and exploiting him financially. He also alleged that the doctors at the hospital concealed details regarding his father’s demise. 

The following allegations were laid against the hospital through a recent video that was shared on social media. In the video, the man explained that his father passed away last month and claimed that the hospital had financially exploited him by withholding information about his father’s death.  

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In response to these accusations, the hospital denied the claims and said that the statements were ‘baseless’. Subsequently, they issued a Rs 2 crore defamation notice against the man on Friday, accusing him of damaging their reputation.    

Shortly thereafter, the man went missing and was later discovered hanging from a tree. According to a TOI news report, the man is reported to have committed suicide over the defamation notice.   

Speaking to the Daily, Hospital owner Dr Sandeep Agarwal said, “His father was admitted to the hospital a month ago with Covid. He passed away from the virus. The man had previously made false statements against the hospital. We issued defamation notices to those involved, including his family. His suicide is unrelated to our actions.”  

On the other hand, the deceased family contends that the hospital’s defamation notice deeply affected him. His brother asserted, “The hospital’s administration forced my brother into suicide by issuing the notice to us.” 

Confirming the man’s suicide, Najibabad Circle Officer Anil Kumar said, “His body was found hanging from a tree in a field on Friday evening. We are yet to receive an official complaint regarding this incident.”

Also read- Himalaya Wellness Corporation Moves To Court Against Hepatologist Over Alleged Defamation, Doctor’s X Account Suspended

Chandigarh: Bringing good news to the postgraduate medical aspirants in Chandigarh, the Government Medical College and Hospital (GMCH), Sector 32, is planning to start an MD programme in tuberculosis and respiratory diseases (TBRD).

Already, the Health Ministry has given its nod for four faculty positions for the recently inaugurated TBRD Department. The Ministry approval comes to strengthen the department with the appointment of one Professor, an Associate Professor and two Assistant Professors, adds Tribune India.

With the realisation of this project, GMCH-32 will become the single hospital in the region to start a specialised course for tuberculosis. 

As per the data shared by the Health Ministry last year, India had a total number of 45,471 MD, MS, and PG Diploma, 4,997 DM and MCh seats. Among these, Chandigarh had a total number of 473 MD/MS seats, and 105 DM/MCh seats.

Also Read: 101,043 MBBS, 45,471 MD, MS, PG Diploma, 4,997 SS seats available across 660 medical colleges in India

Now, as per the latest media report by Tribune India, GMCH-32 is planning to start an MD course in tuberculosis and respiratory diseases (TBRD). Such a move comes at a time when for the year 2023, the city has the highest TB notification rate in the country. It recorded 475 cases per 1,00,000 population.

Commenting on the matter, the Head of the Pulmonary Medicine Department, Dr. Varinder Saini mentioned that the TBRD Department operates at the Section 48 hospital and conducts three OPDs weekly, complemented by two OPDs at the GMCH-32. Therefore, in order to enhance the operational efficiency, additional staff is required. 

Dr. Saini further added the department’s exclusive focus on TB patients and also revealed the plans to start an MD programme in the department, for which the National Medical Commission’s approval is still pending.

Meanwhile, the Director of GMCH, Dr. AK Attri emphasised the hospital’s commitment to provide improved options. Currently, the institute hosts three super-speciality DM courses in neurology, urology, and CTVS.

Apart from this, the GMCH also introduced a DNB Hospital Administration course with plans for an expansion of the seats. Therefore, with the recent approval for the faculties in the TBRD Department, it is expected that the patients will get some relief, especially because the department’s OPD functions in Sector 48 hospital. Dr. Attri further mentioned that efforts are currently underway to introduce advanced and enhanced super-speciality services within the hospital.

Chandigarh-based GMCH-32, which also caters to patients referred from the neighbouring States of Punjab and Haryana is facing a growing demand for super-speciality services. 

In recent years, the hospital experienced a surge in the number of patients, prompting the launch of various super-speciality services. In order to streamline patient care, currently an effort is underway to establish a dedicated super-speciality block.

Also Read: Submit PG Medical Admissions Info Online: NMC Gives Deadline To Medical Colleges

As we step into the New Year, resolutions to quit smoking are common, yet many struggle to stay committed. Overcoming nicotine withdrawal symptoms is challenging, but an expert suggests that one’s diet can aid in the journey to quit smoking successfully.

Ginger is recommended as a helpful tool in curbing the desire to smoke. Sliced ginger pieces, with a sprinkle of black salt, can be placed in the mouth when the urge to smoke arises, effectively reducing the craving.

Spearmint leaves are another suggested remedy. Keeping a supply of washed spearmint leaves and chewing a few when the urge to smoke strikes can provide a temporary distraction, making it easier to resist the temptation to light up.

Indian gooseberry, known for its various health benefits, is highlighted for reducing nicotine cravings. Regularly chewing raw pieces and consuming a glass of water with them every morning is advised to help diminish the desire to smoke. The antioxidant-rich fruit can also aid in eliminating accumulated toxins from regular smoking.

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