Menstrual cycle found to affect women’s reaction time, but not as much as being active

Women performed best on cognitive tests during ovulation but physical activity level had a stronger influence on brain function, according to a new study from researchers at UCL.

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Menstrual cycle found to affect women’s reaction time, but not as much as being active

Women performed best on cognitive tests during ovulation but physical activity level had a stronger influence on brain function, according to a new study from researchers at UCL.

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Housing associations found more effective than government in supporting unemployed in deprived areas of the UK

New research reveals that “third-sector” services, such as those run by housing associations, are far more effective than government work programs at helping the long-term unemployed in deprived areas.

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Housing associations found more effective than government in supporting unemployed in deprived areas of the UK

New research reveals that “third-sector” services, such as those run by housing associations, are far more effective than government work programs at helping the long-term unemployed in deprived areas.

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Digital therapeutic approach to health literacy can enhance patients’ engagement with educational materials

About 93% of U.S. adults access the internet, and 80% of those search for health information, despite low levels of proficiency in health literacy. In a new study, researchers have developed an automated approach to assess how easily understandable patient educational videos are for individuals looking for information on diabetes.

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Portable device could help scientists track Alzheimer’s disease as it unfolds in real time

A team of researchers from Concordia University and McGill University has developed a “lab-on-a-chip” device that models how Alzheimer’s disease advances in the brain.

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Digital therapeutic approach to health literacy can enhance patients’ engagement with educational materials

About 93% of U.S. adults access the internet, and 80% of those search for health information, despite low levels of proficiency in health literacy. In a new study, researchers have developed an automated approach to assess how easily understandable patient educational videos are for individuals looking for information on diabetes.

Powered by WPeMatico

Portable device could help scientists track Alzheimer’s disease as it unfolds in real time

A team of researchers from Concordia University and McGill University has developed a “lab-on-a-chip” device that models how Alzheimer’s disease advances in the brain.

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Patient personas offer insight into health care improvements

To offer the best possible medical treatments, many health care providers and administrators in recent years have started to rely on patient personas.

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Fludrocortisone 0.2 mg Study Rejected by CDSCO Panel Over Potential Adverse Effects

New Delhi: Noting the possible risk of expected adverse effects in healthy subjects, the Subject Expert Committee (SEC), functioning under the Central Drug Standard Control Organization (CDSCO), has declined to recommend a proposed clinical study by Advity Research Private Limited for Fludrocortisone Tablets USP 0.2 mg.

This came after the firm presented the protocol along with published literature of Fludrocortisone Tablet USP 0.2 mg, in light of the earlier SEC recommendation dated 07.08.25.

Fludrocortisone is a mineralocorticoid used to treat adrenocortical insufficiency and salt-losing adrenogenital syndrome.

The main endogenous mineralocorticoid, aldosterone, is produced in the zona glomerulosa of the adrenal cortex—it acts on mineralocorticoid receptors in the kidneys to increase sodium reabsorption and potassium excretion, which in turn helps to regulate plasma electrolyte composition and blood pressure. In conditions of adrenal insufficiency, such as Addison’s disease, aldosterone is not produced (or is produced in insufficient quantities) and must be replaced by exogenous mineralocorticoids such as fludrocortisone.

Also Read: NPPA Fixes Ceiling Price Of Framycetin Cream, Fludrocortisone Tablet

Fludrocortisone binding to mineralocorticoid receptors causes alterations to DNA transcription and translation of proteins that result in an increased density of sodium channels on the apical side of renal tubule cells and an increased density of Na+-K+-ATPase on the basolateral side. These increases in receptor density result in increased plasma sodium concentrations, and thus increased blood pressure, as well as a decreased plasma potassium concentration. Fludrocortisone may also exert a direct effect on plasma sodium levels via action at the Na+-H+ exchanger found in the apical membrane of renal tubule cells.

At the recent SEC meeting for endocrinology and metabolism, the expert panel reviewed the protocol along with published literature of Fludrocortisone Tablet USP 0.2 mg presented by Advity Research Private Limited.

After detailed deliberation, the committee did not recommend the study due to the possible risk of expected adverse effects of Fludrocortisone Tablet USP 0.2 mg in healthy subjects.

Also Read: Hydrocortisone and fludrocortisone combo improves hospital discharge and survival in patients with Sepsis

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