Flatworms could replace rats for in vivo brain studies
Tiny pond worms could help find new ways to treat schizophrenia, develop an understanding of drug addiction and test new medicines for mental illnesses—all while reducing the number of mice and rats used in early medical research.
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Medical pros of electroconvulsive therapy may be exaggerated while cons are downplayed
The medical pros of electroconvulsive therapy (ECT) are being exaggerated while the risks are being downplayed, suggest the findings of a survey on the type of information patients and their relatives/friends recall having been given before the procedure, and published online in the Journal of Medical Ethics.
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Global study finds heart failure drug spironolactone fails to lower cardiovascular risk in dialysis patients
A large international study has found that spironolactone, a medication for high blood pressure and heart failure, does not reduce the risk of heart-related death or hospitalizations in people with kidney failure receiving dialysis, despite earlier smaller studies suggesting benefit.
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Experts recommend SGLT-2 and GLP-1 only for adults at moderate to high risk of heart and kidney problems
SGLT-2 inhibitor and GLP-1 receptor agonist drugs should be used in all or almost all adults with type 2 diabetes at higher risk of cardiovascular and kidney complications, and in the majority of adults at moderate risk of complications, says a panel of international experts in The BMJ.
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ADHD medication linked to reduced risk of suicide, drug abuse, transport accidents and criminal behavior
Drug treatment for people with newly diagnosed attention deficit hyperactivity disorder (ADHD) is associated with significantly reduced risks of suicidal behaviors, substance misuse, transport accidents, and criminality, finds a study published by The BMJ.
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Broad COVID-19 vaccination makes economic sense, especially for older adults, modeling study finds
As the nation gears up for the rollout of an updated COVID-19 vaccine, a new study shows the economic benefits of continued broad vaccination in adults.
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Arginine dentifrices significantly reduce childhood caries, clinical trial finds
A study in JDR Clinical & Translational Research demonstrates that arginine dentifrices reduce dental caries in children with active caries as effectively as or more effectively than a sodium fluoride dentifrice, depending on the arginine concentration.
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Specialized imaging improves overall prostate cancer survival by identifying benefits of salvage radiotherapy
A study from Denmark shows for the first time that men with biochemically recurrent prostate cancer who undergo PSMA PET/CT before salvage radiotherapy have improved survival rates compared to those who do not.
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For professional fighters, childhood disadvantage is linked to more brain changes later
Athletes who participate in combat sports like boxing and mixed martial arts and grow up in disadvantaged neighborhoods may be more likely to show signs of brain changes associated with neurodegeneration than athletes from affluent neighborhoods, according to a study published on August 13, 2025, in Neurology Open Access.
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