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Arexvy was the first vaccine approved in Japan for adults aged 60 years and older for the prevention of RSV disease, and for those aged 50 years and older at increased risk for severe RSV disease.

RSV is a common, contagious virus affecting the lungs and breathing passages impacting an estimated 64 million people of all ages globally every year. RSV can exacerbate certain medical conditions, and lead to severe illness resulting in hospitalisation and even death.

This regulatory submission is supported by positive results from phase IIIb trial NCT063894875 which showed a non-inferior immune response in adults aged 18-49 at increased risk for RSV-LRTD due to certain underlying medical conditions, to that observed in adults aged 60 and above. The safety and reactogenicity data were consistent with results from the phase III programme that supported the initial approval of the vaccine in Japan.

Regulatory submissions to expand the indications for the RSV vaccine continue in other geographies including the US and Europe.

Respiratory syncytial virus vaccine, adjuvanted, contains recombinant glycoprotein F stabilised in the prefusion conformation (RSVPreF3). This antigen is combined with GSK’s proprietary AS01E adjuvant.

The MHLW has approved GSK’s RSV vaccine for the prevention of RSV (respiratory syncytial virus) disease for adults aged 60 years and above and adults aged 50 and older who are considered at increased risk of severe RSV disease. The use of this vaccine should be in accordance with official recommendations. As with any vaccine, a protective immune response may not be elicited in all vaccinees.

The GSK proprietary AS01 adjuvant system contains STIMULON QS-21 adjuvant licensed from Antigenics Inc, a wholly owned subsidiary of Agenus Inc. STIMULON is a trademark of SaponiQx Inc., a subsidiary of Agenus.

Aizawl: Mizoram Health Minister Lalrinpuii has called for urgent and coordinated efforts to address the state’s HIV crisis, as Mizoram continues to record the highest HIV prevalence rate in India at 2.73%. 

Speaking at the governing body meeting of the Mizoram State AIDS Control Society (MSACS) in Aizawl on Wednesday, Lalrinpuii, who also chairs the society, said the situation leaves no room for complacency and requires intensified intervention across sectors, news agency UNI reported.

MSACS Project Director Dr Jane Rinzuali Ralte informed the meeting that 2,069 new cases of People Living with HIV (PLHIV) were registered at the state’s 14 Antiretroviral Therapy (ART) centres during 2024–2025. Of those receiving treatment, 97.7% have achieved viral suppression, meaning they can no longer transmit the virus to others, she said.

Also Read:8 Mizoram Govt Health facilities receive NQAS Certification

While Mizoram remains at the top in terms of HIV prevalence, Ralte noted a steady decline in new cases over the past five years, describing it as a positive trend, though far from satisfactory.

According to a UNI report, as part of its multi-pronged response, MSACS conducted HIV testing and treatment literacy campaigns in de-addiction centres, along with intensive Information, Education and Communication (IEC) outreach across all 11 districts last year. Candlelight vigils were also held in memory of those who lost their lives to HIV/AIDS.

Ralte added that the Mizoram State Blood Transfusion Council (MSBTC) had won the prestigious ‘Excellence in Blood Donation 2023–24’ award, being recognised as the best-performing council in the entire Northeast.

Medical Dialogues had earlier reported that eight government health facilities in Mizoram have been newly ranked among the best-performing public hospitals in India under the National Quality Assurance Standards (NQAS).

According to Dr Lily Chhakchhuak, Mission Director of the National Health Mission under the Health & Family Welfare Department, the newly accredited facilities include Kawnpui PHC (91.42%), Pangzawl PHC (96.26%), Chhingchhip PHC (93.80%), Hrangchalkawn UPHC (93.35%), Lungsen PHC (88.22%), Cherhlun PHC (89.66%), Sangau PHC (89.03%), and Chhuarlung PHC (95.30%).       

Also Read:HMPV Virus Cases: Mizoram forms Committee to address rising concerns

Fractures of the distal radius (near the wrist) and proximal humerus (upper arm near the shoulder) are among the most frequent osteoporotic injuries, especially in adults over age 65. Wrist fractures account for nearly 20% of all emergency departments cases[vii] and are the most common upper limb fracture. Proximal humerus fractures rank third among fragility fractures and represent nearly 6% of all adult cases, an incidence expected to rise with aging populations.

The VOLT Wrist Treatment System was designed in conjunction with the Hand Expert Group within the AO Technical Commission to treat a wide range of fractures.^14‡ This system includes the VOLT Two-Column Distal Radius Rim Plate, which features a new plate shape that allows it to sit more distal to the target distal fragments.^14‡ The plate profile is significantly less prominent in the area of the flexor pollicis longus region.^14‡ These innovations are designed for both simple and complex fracture patterns.^15,16¶

“The plate is less prominent^14‡, sits more distal^14§, and the round, tapered edges are designed to reduce the risk of soft tissue irritation,” said Amy Speeckaert^||, M.D., Orthopedic, Hand and Upper Extremity surgeon in the U.S. “The VOLT™ Distal Radius Plates use the new instrumentation from the VOLT Mini Fragment System which offers an expanded range of implants for fracture reduction and fixation.^1## The hooks of the VOLT™ Two-Column Distal Radius Rim Plate are designed to engage with volar lip where the ligaments meet the bone.”

Additionally, the VOLT Proximal Humerus 3.5 Plating System represents innovation in the treatment of upper arm fractures that involve the shoulder joint. This system adds the flexibility of variable angle locking^5,6,7,8** and includes more plate length options. The plate also features suture holes that are designed for easier suture passage.^20†† The VOLT Locking Screws have also been engineered with an atraumatic tip designed to reduce the risk of soft tissue irritation.^21‡‡

“The new VOLT Proximal Humerus 3.5 Plating System provides more versatility and options^1## with the integration of variable angle locking technology^4†, redesigned suture holes^20†† and broader plate^22¶¶ selection,” said Harry Hoyen^§§, M.D., Orthopedic and Hand surgeon in the U.S. and Simon Lambert^||||, Orthopedic and Trauma surgeon in the U.K., who both serve on the Shoulder and Elbow Task Force within the AO Technical Commission.^#

“The VOLT Wrist Treatment System and VOLT Proximal Humerus 3.5 Plating System are not only a testament to advanced engineering but also reflect a deep understanding of the needs of surgeons and patients,” said Aldo Denti, Company Group Chairman, Orthopaedics, Johnson & Johnson MedTech. “These innovations are designed to provide surgeons with the tools necessary to navigate the complexities of upper extremity fractures with confidence.”

The VOLT Distal Radius and Proximal Humerus 3.5 Plating System, are now commercially available in the U.S., with additional anatomic plating solutions expected to join the platform throughout the next several years. 

Gorakhpur: Uttar Pradesh Chief Minister Yogi Adityanath on Saturday extended heartfelt congratulations on the occasion of the 11th International Day of Yoga (IDY), urging citizens to incorporate yoga into their daily lives to build a healthier and more harmonious society. 

Observed globally every year on June 21, the International Day of Yoga was first proposed by Prime Minister Narendra Modi in 2014 and swiftly adopted by the United Nations, garnering support from 177 countries. Since then, the day has become a global celebration of India’s ancient wellness tradition.

Taking to X, CM Yogi posted, “Hearty congratulations to the people of the state and all yoga practitioners on International Yoga Day! Yoga, the invaluable gift of India’s Rishi tradition, has shown the world the path to mental, spiritual and physical uplift”, news agency IANS reported.

“Come, let us participate in building a healthy society by making yoga a part of our daily routine,” he added.

Also Read:UP launches recruitment drive to fill 4,350 vacant posts in AYUSH Dept

The Chief Minister participated in a special yoga session organised at the Gorakhnath Temple in Gorakhpur, joining hundreds of participants who gathered to mark the occasion with collective practice.

Around the globe, people observed the International Day of Yoga by joining events focused on wellness, mindfulness, and sustainable living.

Prime Minister Narendra Modi led the national event to mark the 11th International Day of Yoga in Visakhapatnam.

Kicking off the IDY, the PM said that yoga gives the world the direction of peace at a time when it is witnessing conflicts, unrest and instability. He urged the international community to let this Yoga Day mark the beginning of yoga for humanity 2.0, where inner peace becomes global policy.

The Prime Minister, who performed the Common Yoga Protocol (CYP) along with over three lakh people at RK Beach, emphasised the importance of yoga in ensuring happiness and peace.

In a parallel event in Haryana, Chief Minister Nayab Singh Saini led a massive yoga session involving nearly one lakh participants on the banks of the sacred Brahma Sarovar in Kurukshetra.

This year’s Yoga Day theme focused on the role of yoga in enhancing not just physical and mental health but also environmental consciousness, echoing the global call for unity, well-being, and sustainable development.

Also Read:Yoga for One Earth, One Health: NMC issues notice for medical colleges for International Yoga day celebrations