Hormone Therapy may lower risk of Allergic Rhinitis in Perimenopausal Women

In a recent study conducted between May 2020 and March 2021 at Shijitan Hospital, researchers explored the complex connections between hormone therapy (HT), obesity, and allergic rhinitis (AR) in perimenopausal women. The study found that HT was found to reduce the risk of AR in perimenopausal women and intriguingly an association was also found between HT, BMI, and AR as lean women on HT exhibited a higher risk for AR compared to overweight women on HT.

The study results were published in the journal Allergy, Asthma and Clinical Immunology.

Also Read: Breakthrough Treatment for Allergic Rhinitis: Intratonsillar Injection Shows Promising Results in Clinical Trial

Mounting evidence indicates that both hormone therapy (HT) and obesity play a role in the development of allergic rhinitis (AR). As it is crucial to explore the connections and interplay between HT, body mass index (BMI), and AR specifically in perimenopausal women researchers from China conducted a study to investigate the association and interactions between HT, BMI, and AR in perimenopausal women.

A cross-sectional survey conducted between May 2020 and March 2021 involved patients from the Allergy and Gynecology Departments of Shijitan Hospital. Participants completed a detailed questionnaire, and BMI tertile-stratified analyses were performed. Logistic analyses were employed to assess relationships between HT, BMI, and AR.

Findings:

  • Out of 950 participants, 393 were undergoing HT.
  • HT was associated with elevated risks for AR, asthma, and their respective symptoms.
  • In lean women, HT usage significantly correlated with increased risks for AR, the duration of AR, hay fever, and accompanying symptoms (including canker sores, diarrhea, and stomachache) compared to normal or heavier-weight counterparts.

The study brought to light an interaction effect between HT and BMI concerning AR. Lean women on HT exhibited a higher risk for AR compared to overweight women on HT. The relationship dynamics revealed an intricate interplay, with the course of AR, hay fever, and accompanying symptoms showing statistically significant interactions.

Also Read: Omalizumab may improve outcomes among patients with chronic rhinosinusitis with nasal polyps independent of allergic status

Contrary to previous assumptions, hormone therapy was found to reduce the risk of AR in perimenopausal women. However, the heightened risk in lean women on HT suggests a nuanced relationship that warrants further exploration. The findings not only contribute to a better understanding of the intricate connections between HT, BMI, and AR but also point towards potential shared pathways between hormone therapy and obesity in influencing allergic rhinitis.

Further reading: Liu J, Ma T, Wang X, Bai W, Wang X. Associations between HT, BMI, and allergic rhinitis in perimenopausal women. Allergy Asthma Clin Immunol. 2023;19(1):107. Published 2023 Dec 19. doi:10.1186/s13223-023-00839-7

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Waist Circumference Linked to Female Infertility: Study Reveals Impact Beyond BMI

In a groundbreaking study utilizing data from the National Health and Nutrition Examination Survey (NHANES), researchers have unveiled a significant association between waist circumference (WC) and female infertility among women of childbearing age in the United States. The findings suggest that beyond BMI, waist circumference may play a significant role in female infertility, and engagement in moderate recreational activities could potentially mitigate the risk associated with abdominal obesity.

The study results were published in the journal PLOS One.

Also Read: Women’s risk of infertility increases by 3% for every Kg of weight gained

Obesity carries noteworthy consequences for fertility and reproductive health. Nevertheless, the evidence connecting abdominal obesity to female infertility has been both limited and inconclusive. Hence, researchers aimed to elucidate the possible correlation between waist circumference (WC) and infertility in women of childbearing age in the United States, utilizing data from the National Health and Nutrition Examination Survey.

The cross-sectional study involved 3239 female participants aged 18–45 years. Employing weighted multivariable logistic regression and smoothed curve fitting, the researchers sought to disentangle the influence of waist circumference from other factors, including BMI and potential confounders.

Findings:

  • The results revealed a positive and independent association between waist circumference and female infertility.
  • Even after adjusting for BMI and other confounding variables, every 1cm increase in waist circumference was associated with a 3% rise in the risk of infertility (OR = 1.03, 95% CI: 1.01–1.06).
  • Stratifying WC into quintiles highlighted a striking 2.64 times higher risk of infertility in women in the highest quintile compared to those in the lowest quintile (OR = 2.64, 95% CI: 1.31–5.30).
  • The relationship between WC and infertility was further nuanced by activity levels.
  • Smooth curve fitting revealed a non-linear, dose-dependent association.
  • Intriguingly, an inverted U-shaped relationship emerged in participants engaged in moderate recreational activities, with a turning point at 113.5 cm.
  • For those with deficient recreational activities, a J-shaped relationship was observed, with a turning point at 103 cm.

The study’s conclusions emphasize the significance of waist circumference as an independent predictor of female infertility, irrespective of BMI. This challenges conventional notions that solely focusing on overall obesity metrics suffices in understanding reproductive health implications.

Also Read: Are intracavernosal injections of platelet-rich plasma effective against erectile dysfunction?

Moreover, the findings shed light on the potential protective role of moderate recreational activities. Women engaging in such activities exhibited a lower risk of infertility associated with abdominal obesity. This underscores the importance of not only addressing weight-related factors but also considering lifestyle and physical activity in the context of reproductive health.

Further reading: Association between waist circumference and female infertility in the United States. https://doi.org/10.1371/journal.pone.0295360

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Aspirin tied to reduced risk of mortality, sepsis, and shock among IBD patients

Inflammatory bowel disease (IBD) is a chronic inflammatory disorder affecting the gastrointestinal tract, including Crohn’s disease (CD) and ulcerative colitis (UC). IBD affects over 1 million people in the US and is linked to increased short- and long-term mortality. CD and UC are influenced by microbial, genetic, immune, and environmental factors.

In a study published in the International Journal of Colorectal Disease, Humzah Iqbal et al. and colleagues found that aspirin usage in IBD patients is associated with a reduced risk of mortality, sepsis, and shock. Aspirin may offer protective effects in IBD patients.

IBD can increase the mortality risk. Aspirin is an anti-inflammatory drug used for primary prevention of cardiovascular events. However, the impact of aspirin use on significant outcomes in IBD remains unclear.

The NIS (National Inpatient Sample) 2016-2020 was used to identify adult IBD patients, with data collected on demographics, hospital characteristics, and comorbidities. The study analyzed in-hospital mortality, sepsis, shock, ICU admission, and surgery needs using multivariate logistic regression.

The study could be summarised as follows:

  • The study included 1,524,820 IBD hospitalizations.
  • 137,430 patients were long-term aspirin users.
  • In the aspirin group, 34% of patients were aged > 65 years, 56% were female, 78% were White, and 36% had Medicare insurance.
  • Aspirin users had a lower incidence of in-hospital mortality (1.6% vs 1.4%), sepsis (2.5% vs 2.9%), shock (2.9% vs 3.4%), ICU admission (2.6% vs 2.9%), and surgery need (2.1% vs 4.2%).
  • After adjusting for confounders, aspirin was associated with a reduction in mortality having adjusted odds ratio of 0.49.

They said, Our study used an extensive NIS database to assess the outcomes of patients hospitalized with IBD taking aspirin. Previous literature has shown that White patients are more likely to be taking long-term aspirin even when controlling for cardiovascular risk factors. These findings suggest that the study sample is representative of the population taking aspirin. The study also found lower odds of surgical intervention in patients with long-term aspirin use, which may be due to the effect of aspirin on the disease activity among IBD patients. The incidence of surgical intervention in the study was 4%.

Reference:

Iqbal H et al. The impact of aspirin use on outcomes in patients with inflammatory bowel disease: Insights from a national database. Int J Colorectal Dis. 2023 Dec 20;39(1):6

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Telepsychiatry fails to replace in-person counselling: Study

India: A recent study published in Consortium Psychiatricum showed that patients reported moderate or even low satisfaction with sessions of a telepsychiatry service, however, the doctor’s attitude to the online service was positive. 

Researchers from Dr. Ram Manohar Lohia Institute of Medical Sciences, working in collaboration with their colleges from Era’s Lucknow Medical College & Hospital, as well as the Institute of Human Behaviour and Allied Sciences in New Delhi have found out why the patients did not like the “remote” treatment. 

Because of the lockdown during the pandemic, mentally ill patients could not get in-person psychiatric counseling on a regular basis. To solve this problem, a telepsychiatry service was created in India that helped patients to talk with their doctors while safely staying at home.

In the era of rapid distribution and implementation of digital technologies, telepsychiatry can potentially become an easier, more convenient and cost-effective way for patients to get psychiatric care. But how effective are virtual doctor-patient conversations?

The researchers surveyed 100 subjects to find the answer to this question. All subjects were followed up by psychiatrists for various disorders such as major depression, bipolar and anxiety disorders, obsessive-compulsive disorder or tension headaches accompanied by mild psychiatric symptoms. The patients had been coming for in-person consultations with a psychiatrist for two years before the pandemic, and during the lockdown, they were offered free psychiatric counselling using video conferencing via a special hospital mobile app.

The study subjects got two 15- to 20-minute consultations with a two-week interval. After the second consultation, they were asked to complete the Client Satisfaction Questionnaire-8 (CSQ-8) in a Google form for easier interaction. Then the researchers conducted the statistical data analysis to evaluate the degree of patients’ satisfaction.

The lowest degree of satisfaction was associated with the question “Has the provided medical care helped you overcome your issues more effectively?” over the past two weeks – 61% of patients said no. The next question was “How would you assess the quality of provided care?” 55% of respondents reported poor quality of the provided care. When answering the question “In general, to what extent are you satisfied with the care you have received?”, about 53% of patients reported being dissatisfied or partially satisfied with the care they had been provided.

At the same time, despite admitting the low effectiveness of two virtual sessions, many patients were ready to use the service again (72%) or recommend it to a friend (67%). More than half of respondents said they had received the care they had wanted but to a lesser extent or of poorer quality.

Patients’ demographic characteristics did not significantly affect their responses; however, people living in cities tended to be more satisfied with the remote treatment (most likely due to the fact that they were used to online communication), and so did patients from low-income communities who could not probably afford to get paid psychiatric care.

The doctors suggested that cultural differences of patients from Central Asia and misinterpretation of the patients’ emotions on the screen played a role in the patients’ negative impression of the sessions.

Patients who are satisfied with the process and the outcome of treatment are more adherent to therapy and more likely to have better prognosis. This shows the importance of surveys evaluating patients’ satisfaction: they reveal weaknesses and disadvantages of provided medical care and therefore help healthcare decision-makers develop more effective mental health programs. In this case, too, the feedback from patients regarding the telepsychiatry service may be used to develop guidelines for practice.

According to one of the authors of the study, Dr. Abdul Q Jilani, in the coming decades, online consultations may rise exponentially as it avoid the inconvenience travelling barriers and indirect medical expenses, especially for the follow-up of stable patients.

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Isotretinoin as adjuvant to rhinoplasty increases cosmesis and patient satisfaction

Use of Isotretinoin as an adjuvant to rhinoplasty may increase cosmetic and patient satisfaction suggests a new study published in the International Journal of Dermatology. 

Isotretinoin has been used in the treatment of acne for decades through the reduction of sebaceous secretion. There are reports in the literature that isotretinoin may be associated with decreased skin thickness, especially in patients with thick nasal skin for whom rhinoplasty can be more challenging. The objective of this study was to quantify, through ultrasonography, the effect of the use of oral isotretinoin in patients undergoing rhinoplasty, pre- and postoperatively.

Twenty-four patients participated in this randomized, single-blind controlled pilot clinical trial. The intervention group used oral isotretinoin (20 mg/day) for 2 months before rhinoplasty and for 4 months after. Both groups underwent rhinoplasty in the same plastic surgery department and were submitted to high-frequency (22 MHz) ultrasound evaluation of the epidermis and dermis on the nasal dorsum, nasal tip, and left nose wing at the beginning of the study and 6 months after rhinoplasty, with the aim of assessing changes in skin thickness.

Results

Six months after rhinoplasty, a statistically significant reduction was observed in the thickness of the epidermis and dermis of the nasal dorsum and left nose wing, as well as of the epidermis of the nasal tip, but only in the intervention group. The results of the satisfaction questionnaire were better after rhinoplasty in both groups, with no statistical difference between them regarding the specific questions; however, the intervention group had significantly higher satisfaction scores than the control group.

Isotretinoin was effective in reducing the thickness of the skin covering the nose of the evaluated sites.

Reference:

Silveira, C.S.C., Azulay-Abulafia, L., Barcaui, E.O., Silva, M.M.M. and Roxo, A.C.W. (2023), Analysis of the use of isotretinoin as an adjuvant in rhinoplasty. Int J Dermatol. https://doi.org/10.1111/ijd.16924

Keywords:

Use, Isotretinoin, adjuvant, rhinoplasty, may, increase, cosmetic, patient, satisfaction, Silveira, C.S.C., Azulay-Abulafia, L., Barcaui, E.O., Silva, M.M.M. and Roxo, A.C.W.

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Intensive Food-as-Medicine Program fails to improve Glycemic control in diabetes patients: JAMA

The growing prevalence of food-as-medicine programs necessitates robust evidence to assess their impact on health.

A recent JAMA Internal Medicine concluded that an intensive food-as-medicine program boosts engagement in preventive health care. Still, it didn’t enhance glycemic control compared to standard care among adult participants. Programs for people with high biomarkers need a control group to show effectiveness. More research is required to develop food-as-medicine programs promoting better health outcomes.

This study determined if an intensive food-as-medicine program for diabetes patients and food insecurity can improve glycemic control and affect healthcare use. The study was conducted as a stratified randomized clinical trial with a waitlist design from April 19, 2019, to September 16, 2022. Participants were followed for one year and were randomly assigned to either the treatment group, which participated in the program immediately, or the control group, which waited six months. The trial took place at two sites, one rural and one urban. To be eligible for the study, participants required a T2D diagnosis, HbA1c level of 8% or higher, food insecurity, and residence within the service area of the participating clinics.

The program offered healthy groceries for ten meals/week, plus consultations, evaluations, coaching, and diabetes education for a year. The primary outcome was HbA1c at six months, with secondary outcomes including biometric measures, healthcare use, and self-reported diet/healthy behaviours at 6 and 12 months

The summary of this study includes the following points:

· Of 3712 patients assessed, 3168 were contacted, 1064 were deemed eligible, 500 consented and were randomized, and 465 patients completed the study.

· Of these, 349 patients had laboratory test results at six months. Both treatment and control groups experienced a decline in HbA1c levels, resulting in a non-significant adjusted mean difference of -0.10.

· Access to the program increased preventive health care, including more dietitian visits, active prescription drug orders for metformin and glucagon-like peptide one medication, and participants reporting improved diets.

This clinical trial showed that an intensive food-as-medicine program improved engagement with preventive health care but didn’t affect glycemic control compared to usual care. Control groups are necessary to demonstrate effectiveness in programs targeting individuals with elevated biomarkers. More research is needed to design food-as-medicine programs that improve health.

Reference:

Doyle J et al.Effect of an Intensive Food-as-Medicine Program on Health and Health Care Use: A Randomized Clinical Trial. JAMA Intern Med.

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Preoperative carbohydrate intake linked to Success of surgery of Osteoporotic fractures in Elderly

In a groundbreaking study conducted at a prominent Chinese institution, researchers have unveiled a promising connection between preoperative oral carbohydrate (CHO) intake and improved outcomes for elderly patients undergoing surgical treatment for osteoporotic fractures (OPFs). The study addressed the notable gap in the utilization of this practice and concluded that preoperative oral CHO intake may correlate with reduced mortality risk and improved outcomes in elderly patients undergoing surgical treatment for OPFs.

The study results were published in the Journal of Orthopedic Surgery and Research.

Also Read: PFAS exposure tied to reduced bone health in adolescents and young adults

Despite the well-established benefits of preoperative CHO intake, its underutilization, especially among older patients facing orthopedic surgery for OPFs, has raised eyebrows. This prompted a comprehensive retrospective cohort study, enrolling 879 elderly patients, with a median age of 71 years, to investigate the potential correlation between preoperative oral CHO consumption and surgical outcomes.

The study, conducted at a single Chinese institution, implemented stringent exclusion criteria and utilized propensity score matching to ensure a balanced analysis. The  exclusion criteria were: 

  1. The necessity for urgent surgical intervention
  2. The existence of hypoglycemia, hyperglycemia, or diabetes mellitus with blood glucose levels lower than 2.8 mmol/L
  3. A medical history of gastrointestinal motility disorders or delayed gastric emptying
  4. The utilization of local anesthesia
  5. A Charlson comorbidity index (CCI) score over 2
  6. An American Society of Anesthesiologists (ASA) score exceeding 3.

 After matching, 264 patients in each cohort were subjected to rigorous evaluation, focusing on primary outcomes such as the 60-day all-cause mortality rate, and secondary outcomes, including the length of hospital stay (LOS), hospitalization costs, blood transfusions, and postoperative complications. 

Key Findings:

  • Post-propensity score matching, the study yielded compelling results.
  • Patients who received preoperative oral CHO intake exhibited a significant negative association with 60-day mortality in the fully adjusted model.
  • Moreover, these individuals experienced a shorter LOS and incurred lower hospitalization costs compared to their counterparts.
  • Notably, no significant associations were found between CHO intake and postoperative nausea and vomiting (PONV) or blood transfusion risks.
  • Equally noteworthy was the absence of reported cases of aspiration in either cohort.
Also Read:Study: Spinal cord injury causes acute and systemic muscle wasting

The study’s findings suggest that incorporating preoperative oral CHO intake could be a game-changer in enhancing outcomes for elderly patients undergoing surgical treatment for OPFs. By demonstrating a potential reduction in mortality risk and improved postoperative experiences, the study paves the way for a shift in preoperative care practices.

Limitations:

While the results are promising, the study acknowledges its limitations, including its retrospective nature and the confined scope of participation to a single institution. To solidify and expand upon these findings, the researchers call for future endeavors with larger sample sizes and extended follow-up periods. This would enable a more comprehensive exploration of the long-term impact of preoperative CHO intake and a deeper understanding of the underlying mechanisms at play. 

Further reading: Zhu et al. The association between oral carbohydrate intake before orthopedic surgery for osteoporotic fractures and outcomes in elderly patients. Journal of Orthopaedic Surgery and Research (2023) 18:966. https://doi.org/10.1186/s13018-023-04458-1

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Rare case of Severe Hypoglycemia in diabetes patient Following Anesthesia Induction: A report

Acute severe hypoglycemia immediately following anesthesia induction is a rare but life-threatening complication that is frequently underdiagnosed due to insufficient awareness

A recent case analysis found acute severe hypoglycemia immediately following anesthesia induction in the perioperative setting. The key observations by Qin Tian and team were published in the Journal of Medicine.

The case report found that after examining the case of an 89 year old man with type 2 diabetes mellitus, he experienced a dramatic drop in blood glucose levels from a baseline of 4.0 mmol/L to a perilous 0.96 mmol/L immediately after the induction of anesthesia. More importantly, the patient displayed normal insulin, C-peptide, and cortisol levels, thereby eliminating other potential causes that lead to hypoglycemia. The temporal association and rapid decline implicated opioids as the likely impact.

After the diagnosis, the patient received a prompt intervention of 40 ml of 50% dextrose intravenously which was followed by a 5% dextrose infusion. Fortunately, recovery from anesthesia was uneventful with no further hypoglycemic episodes during the period of hospitalization.

This case report highlights the often-neglected connection between opioids and severe hypoglycemia during anesthesia. Thereby, the outcomes observed emphasize the necessity for vigilant glucose monitoring in the perioperative period. The implications of this research extend beyond just this one case which points to a broader need for awareness among clinical anesthesiologists. This case report altogether reassures that timely diagnosis can be pivotal in averting life-threatening hypoglycemic events with safer outcomes in the field of anesthesia. Prompted by the life-threatening complications of this rare but underdiagnosed occurrence, this case report underscores the critical need for increased awareness and vigilant glucose monitoring during procedures involving anesthesia.

Source:

Tian, Q., Yi, M. L., Wan, J. L., & Yin, H. (2023). Acute severe hypoglycemia immediately after induction of anesthesia in an elderly patient with type 2 diabetes mellitus: A case report. In Medicine (Vol. 102, Issue 51, p. e36683). Ovid Technologies (Wolters Kluwer Health). https://doi.org/10.1097/md.0000000000036683

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Kolkata doctor arrested for allegedly raping, holding18-year-old nurse captive

Kolkata: In a shocking incident, a doctor has been arrested for allegedly raping, holding a 18-year-old nurse captive for several days at his private nursing home in New Town area in Kolkata.

Subsequently, the nurse filed a complaint at the local police station on December 23, leading to the registration of an FIR under various relevant sections. The doctor was arrested on Sunday after substantial evidence was gathered during the preliminary investigation.

According to the complainant, she had been employed at the nursing home for the past two months. On December 12, the doctor allegedly summoned her to his chamber around noon and subjected her to sexual assault. Disturbingly, she asserted that he forcibly confined her within the nursing home, issuing threats of harm if she revealed the incident. 

Also read- Doctor Arrested For Allegedly Sexually Assaulting Nurse At Delhi Clinic

As per a TOI news report, the nurse alleged that she was raped and held captive for around five days in the doctor’s chamber in the nursing home. In search of an opportunity, the nurse managed to escape on December 17. 

After the alleged assault, she made her way home. It was only later that she disclosed the traumatic experience to her family. Summoning courage, she officially reported the incident on December 23, prompting the authorities to take swift action.

An officer involved in the case remarked, “The nurse alleged that she had been raped by the doctor who owned the nursing home. Following her complaint, we nabbed the accused on Sunday and produced him in Barasat court. The nurse underwent a medical test.”

An investigation into the case is underway. 

Medical dialogues team had earlier reported that a doctor was booked for allegedly sexually assaulting a nurse on the pretext of marriage in Bhopal’s Sukhi Sewania. The nurse was a 40-year-old woman who worked at the doctor’s private hospital when she was subject to sexual assault.

Also read- Bhopal Nurse Files Complaint Alleging Rape By Doctor On Pretext Of Marriage

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Dehydration affects shade of teeth and may look them whiter

Lebanon: A prospective in vivo study published in Cureus has shed light on the effect of dehydration on tooth colour.

The researchers showed that dehydration impacted the teeth’s shade: lightness increased, and therefore, the teeth appeared whiter.

“Dentists should consider the teeth’s hydration status when evaluating colour for treatments, as there is a significant impact of dehydration on shade matching: the more the dehydration time elapses, there is more increase in the colour difference compared to the baseline,” the researchers wrote.

In dentistry, the teeth’s shade is an essential factor that determines the aesthetics, and the patient’s satisfaction. Therefore, shade matching is a crucial step that reflects the success of the aesthetic restoration outcome. According to several technicians and dentists, this step represents the major challenge. Thus, particular importance must be given to it.

The impact of dehydration on tooth shade constitutes a significant, making it an important area of study, specifically within the field of restorative dentistry. Céline Alamé and Carina Mehanna Zogheib from Saint Joseph University in Beirut, LBN, and colleagues aimed to evaluate the effect of dehydration on the shade of the teeth using a spectrophotometer in a prospective study.

The following null hypotheses were tested: (1) The shade of the teeth does not vary according to their hydration degree, and (2) the ability of shade matching could be conducted at any given time.

For this purpose, the researchers recruited twenty-five participants; the study was conducted between October 2022 and January 2023. The study’s inclusion criteria primarily comprised four intact maxillary incisors. Cavities, damage, restorations, and staining served as exclusion criteria.

The measurements were recorded using the VITA Easyshade Advance spectrophotometer. The measures of L (representing darkness to lightness), a (representing greenness to redness), and b (representing blueness to yellowness) were registered at the centre of each tooth’s labial surface at baseline and then at 10-minute intervals for 30 minutes while the teeth were dehydrating due to rubber dam placement.

Calculation of the colour difference (ΔE) was done using L*a*b* measures, with the perceptibility threshold set at ΔE00=0.8. Statistical analyses were performed using the Bonferroni post hoc test, the Friedman test, and the Wilcoxon signed-rank test.

The study led to the following findings:

· The different colour changes represented by ΔE (ΔE1, ΔE2, and ΔE3) were significantly higher than the perceptibility threshold of 0.8.

· A statistically significant difference was found between ΔE1 and ΔE3.

· A statistically significant difference was found between L0, L10, L20, and L30.

· Statistically significant differences exist between the means of L0 and L20, the means of L0 and L30, the means of L10 and L20, and the means of L10 and L30.

The study concluded that there is a significant impact of teeth dehydration on teeth shade, particularly affecting the perception of whiteness. The dehydration time duration directly corresponds to the extent of colour difference from the baseline. This strongly refutes the initial hypotheses, asserting that teeth shade remains constant irrespective of hydration status and that shade matching can be indiscriminately performed at any time during a dental procedure.

“These findings emphasize the importance of carrying out shade matching before any procedure leading to teeth dehydration, such as rubber dam isolation,” the researchers wrote. “We hope that these insights will guide dental practitioners in augmenting their shade-matching practices, ultimately improving patient satisfaction.”

“Further research would be needed that might focus on identifying ways to reduce the impact of hydration on colour change or developing more adaptive shade-matching techniques that account for teeth hydration levels,” they concluded.

Reference:

Alamé C, Mehanna Zogheib C (November 02, 2023) The Effect of Dehydration on Tooth Color: A Prospective In Vivo Study. Cureus 15(11): e48140. doi:10.7759/cureus.48140

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