A ‘gentle touch’ molecule confers light tactile sensation in humans—and perhaps in individual cells

You were probably taught that we have five senses: sight, sound, smell, taste and touch. This is not quite right: “touch” is not a single sense, but rather several working together.

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Gut microbiome: Meet Bifidobacterium breve, keeping babies healthy

Bifidobacterium breve, or B breve for short, is a bacterial species that’s found in the human intestine. It’s especially relevant in early life, being one of the most abundant bacteria in the newborn gut.

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Rs 671 crore Collected from MBBS Doctors As Bond Penalty: Gujarat Health Minister

Gandhinagar: Altogether Rs 671 crore has been collected from the MBBS doctors as a penalty for non-completion of mandatory rural service, the State Health Minister of Gujarat Rushikesh Patel stated recently.

He further added that another Rs 270 crore is yet to be recovered from such doctors who do not wish to serve the rural areas for one year after completing their education.

As per the government policy, students who get to avail the benefit of subsidized medical education, are required to sign a bond promising to work in the State Government’s Health setup in the rural areas.

The bond conditions specify that the doctors will have to pay Rs 20 lakh as a bond penalty if they fail to fulfill their bond obligations. Commenting on the matter, the Minister said, “Those who do not wish to complete the bond period are required to pay Rs 20 lakh.”

Also Read: Gujarat Clinical Establishments Act to be amended, Registration to become Mandatory for All hospitals

As per the latest media report by the Times of India, the Minister was also asked about the steps taken by the Government against the students who do not wish to complete the bond period. Responding to this, the Minister informed that the State Government cannot stop the universities from conferring medical degrees on the students. 

Responding to these statements made by the MLAs that there is a shortage of medical doctors in the PHCs, CHCs, district hospitals and civil hospitals, the Minister informed that as of date, the State has 7,050 medical seats available, and this number is increasing steadily. He further informed that in the past two years, 1,350 new MBBS seats have been added to the seat matrix.

“The policy of appointing class 1 medical officers is clear. All MD and MS doctors interested in working in the govt will be directly appointed. As for class 2 medical officers, the govt recently gave appointment letters to about 500 candidates through the GPSC, but many of them did not accept because they were pursuing higher studies or were practising,” informed the Minister.

Medical Dialogues had earlier reported that last year the Gujarat Government formulated a new bond policy for doctors who fail to adhere to their service bonds after completing both MBBS and Postgraduate medical courses. As per the new policy, doctors will have to serve only one-and-a-half years instead of the mandatory service of two years.

This proposal for the new bond policy was announced by State Health Minister Rushikesh Patel during the Question Hour at the State Assembly. The Minister had informed that the student has to pay Rs 20 lakh bond fee for MBBS and Rs 40 lakh for the PG course for freeing from the bond.

Also Read: New Bond Policy: Gujarat proposes 1.5 years of Mandatory Service for doctors completing MBBS, PG degree

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ICMR to provide free genetic testing for rare diseases

Mumbai: In a bid to counter the burden of rare diseases in the country, ICMR’s National Institute for Research in Reproductive and Child Health (ICMR-NIRRCH) on Wednesday announced to offer free genetic testing and counselling services. 

Rare diseases are typically chronic and progressive medical conditions that pose life-threatening risks to those affected. Out of the 350 million patients suffering from rare disease globally, India alone is home to approximately 72-96 million patients, according to the Ministry of Health and Family Welfare (MoHFW).

Also Read:Indiscreet prescribing of antibiotics is key contributor to microbial resistance nationwide: MoS Health

The new Genetic Research Centre (GRC) will assess clinically abnormal cases of rare paediatric diseases as well as track origins of undiagnosed genetic disorders. It also aims to facilitate timely therapeutic interventions and provide critical support for both patients and their families.

The centre also holds approval under Pre-Conception and Pre-Natal Diagnostic Techniques Act, 1994 (PCPNDT) to conduct genetic counselling and testing.

While the GRC is currently offering its services in Maharashtra, people with rare diseases from other parts of the country can avail the services, ICMR-NIRRCH said.

“Strengthening access to genetic testing and counselling for rare diseases will pave the way for their early diagnosis and timely intervention, helping improve the health and wellbeing of some of the most vulnerable sections of society. This is a revolutionary step that can transform several lives, especially young lives in the country,” said Dr Geetanjali Sachdeva, Director, ICMR-NIRRCH, in a statement.

With no approved treatment for 95 per cent of rare diseases, the diagnosis of rare diseases is challenging. While early genetic testing is key, diagnosis is conducted through a distinctive blend of clinical and laboratory methods, including cytogenetic, biochemical, and molecular approaches.

At present, the centre is providing its services to around 570 families yearly, covering genetic conditions during infancy, childhood, and adolescence, as well as for reproductive difficulties faced by couples.

“Our centre is working to address a critical public health concern. By reaching out to special schools, hospitals and the public, we are striving to raise awareness around rare diseases and enhance uptake of essential testing and counselling. In doing so, we aim to mitigate the societal burden of these diseases and realise the national goal of a healthy society, with universal access to healthcare services,” said Dr Shailesh Pande, Medical Geneticist and Head GRC, in the statement.

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RSV vaccine Abrysvo is protective through a second year: Pfizer

New York: Pfizer has said a single dose of its new respiratory syncytial virus (RSV) vaccine Abrysvo maintained its ability to protect against the illness through a second year of respiratory disease season.

The company said in a press release that the vaccine’s efficacy against RSV-associated lower respiratory tract disease with three or more symptoms was 77.8 per cent through season two, compared with efficacy of 88.9 per cent after the first RSV season, which led to the shot’s U.S. approval.
The data is from a late-stage trial of more than 37,000 participants being conducted in both the Northern and Southern hemispheres.
Cumulative efficacy over both seasons after around 16.4 months of disease surveillance was 81.5 per cent, Pfizer said.
The data is similar to the efficacy of GSK’s rival RSV shot Arexvy over two seasons, which was released in June.
Both companies launched their RSV vaccines in the U.S. last year. Pfizer Chief Executive Albert Bourla has called his company’s launch a disappointment, after taking only around 35 per cent market share in the first season.
Pfizer said no new adverse events cropped up through the second RSV season beyond those reported in the clinical trial during the first season.
The company plans to submit the new data to regulatory authorities and publish these findings in a scientific journal.

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AbbVie, OSE Immunotherapeutics collaborate to develop novel monoclonal antibody for Chronic Inflammation

North Chicago, Ill.: AbbVie Inc. and OSE Immunotherapeutics SA, a clinical-stage immunotherapy company, have announced a strategic partnership to develop OSE-230, a monoclonal antibody designed to resolve chronic and severe inflammation, currently in the pre-clinical development stage.

OSE-230 is a first-in-class monoclonal antibody designed to activate ChemR23, a G-Protein Coupled Receptor (GPCR) target. Activation of ChemR23 may offer a novel mechanism for the resolution of chronic inflammation, modulating functions of both macrophages and neutrophils.

“This collaboration underscores our commitment to expanding our immunology portfolio with the ultimate goal of improving the standard of care for patients living with inflammatory diseases globally,” said Jonathon Sedgwick, Ph.D., senior vice president and global head of discovery research, AbbVie. “By leveraging our expertise in immunology drug development, we look forward to advancing OSE-230, which offers a novel mechanism-of-action to treat chronic inflammation.”

“We are very pleased to collaborate with AbbVie, a global leader in the development and commercialization of innovative medicines, to drive our OSE-230 program forward,” said Nicolas Poirier, chief executive officer, OSE Immunotherapeutics. “This partnership represents a major milestone in our company’s progress and recognizes the value of our innovative R&D capabilities. I would like to thank all our employees who helped us reach this milestone through dedication and hard work.”

Under the terms of the agreement, AbbVie will receive an exclusive global license to develop, manufacture and commercialize OSE-230. OSE Immunotherapeutics will receive a $48 million upfront payment and will be eligible to receive up to an additional $665 million in clinical development, regulatory and commercial milestones. In addition, OSE Immunotherapeutics will be eligible to receive potential tiered royalties on global net sales of OSE-230.

The transaction is subject to the satisfaction of customary closing conditions, including the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act.

Read also: AbbVie, Tentarix collaborate to develop conditionally-active, multi-specific biologics for oncology, immunology

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Rare case of Half Uterus: Doctors at CK Birla Hospital successfully treats 27-year-old woman

Gurugram: In a groundbreaking medical achievement, doctors here on Thursday said they have successfully treated an extremely rare case of half uterus, known as adenomyosis in a non-communicating rudimentary horn – the first-ever in India. 

“This case is the second reported worldwide, with the first case documented at the Lebanese American University Center in July 2021,” said doctors at C.K. Birla Hospital, Gurugram, in a statement. 

The patient, a 27-year-old woman, sought medical attention due to pelvic pressure, constant pain on the right side of her lower abdomen and pelvis. She was also unable to conceive.  

Also Read:4.5 kg tumour removed from patient’s breast at CK Birla Hospital

Clinical examinations revealed a large firm lump which deviated to the right side of the lower abdomen. The doctors initially suspected a fibroid. But detailed diagnostic hysteroscopy and robotic myomectomy (adenomyoma removal) with chromopertubation revealed that the woman had a left unicornuate uterus with adenomyosis in the non-communicating right horn, attached to a large fibroid-like mass.

This challenging anomaly required meticulous dissection and extraction, taking care to preserve surrounding structures like the intestines and urinary bladder, the doctors said.

“The adenomyoma in the non-communicating horn presented a unique challenge. With careful dissection, we successfully removed the adenomyoma, saving the ureter on the right side. The rarity of a functioning non-communicating rudimentary horn, coupled with adenomyosis, makes this case exceptional. The successful treatment involved a complete robotic-assisted excision of the entire horn, leading to significant improvement in the patient’s condition,” Dr Aruna Kalra, Director, Obstetrics and Gynaecology, at the hospital, said.

“The final histopathology confirmed the presence of adenomyosis in the rudimentary horn, adding a valuable contribution to the limited cases reported globally. The clinical presentation of such cases can vary from mild pain to complications such as pelvic pain, endometriosis, or obstetrical issues like preterm delivery and ectopic pregnancy,” Dr Kalra added.

The patient was discharged the next day and is expected to begin her fertility journey soon, the doctor said.

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AIIMS Delhi Redevelopment: NBCC sells commercial space in South Delhi for Rs 273 crore

New Delhi: NBCC (India) Ltd has e-auctioned about 61,000 square feet of commercial area in South Delhi for Rs 273 crore for constructing residential units for the faculty and staff of the All India Institute of Medical Sciences (AIIMS) New Delhi. 

The property is located at Ayurvigyan Nagar, South Delhi. The amount will be used for the construction of housing for the faculty and staff members of AIIMS Delhi.

The transaction is valued at Rs 272.68 crore, it added. 

Also Read:Virtual autopsy at Delhi AIIMS now a nodal centre for other such institutes

The buyer Grid Controller of India Ltd, a PSU under the Ministry of Power, has secured this deal at a basic sale price of Rs 36,000 per square feet.

This commercial space is part of the ambitious redevelopment project spearheaded by NBCC for the All India Institute of Medical Sciences (AIIMS) Delhi.

As per a media report in the Business Standard, The proceeds from the sale will be utilized for constructing residences for AIIMS Delhi faculty and staff. The project, known as Grande Rue, offers parking for 150 cars across 3 levels of basement and comprises ground and 3 storeys of commercial space. Centrally located in the prime area of South Delhi, it features good connectivity and is nestled within the city’s business hub.

Medical Dialogues team had earlier reported that Prime Minister Narendra Modi virtually inaugurated the 960-bed All India Institute of Medical Sciences (AIIMS) Kalyani in West Bengal’s Nadia district. West Bengal Governor CV Ananda Bose and Union ministers Sarbananda Sonowal, Santanu Thakur, Subhas Sarkar, Nishit Pramanik and John Barla attended the inauguration event from the AIIMS campus. AIIMS Kalyani, the OPD of which has been operational since 2019, is spread over 179.8 acres of land and currently serves around 2,000 patients daily. 

The institute has already inducted around 500 MBBS and 200 nursing students and also started postgraduate and para-medical training initiatives. 

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Diploma in Dental Hygiene and Dental Mechanics 2024-2025: AIIMS Kalyani releases prospectus for Admission, all details here

West Bengal- The All India Institute of Medical Sciences (AIIMS), Kalyani, West Bengal, has issued a prospectus for enrollment in the Diploma programs for Dental Hygiene and Dental Mechanics for the academic session 2024-2025.

Department of Dentistry, AIIMS, Kalyani has hence invited applications for a Diploma in Dental Hygiene and a Diploma in Dental Mechanics.

DETAILS OF COURSE

Duration- 2 years (Regular- Full time).

Admission- January & July (Bi-annual).

DISTRIBUTION OF SEATS

There are total 04 seats for each course and the distribution of seats will be as per the constitutional reservation of the Government of India.

Course

No. of Seats

Category

Diploma in Dental Hygiene

02

02 (UR)

Diploma in Dental Mechanics

02

01 (UR) & 01 (OBC)

DETAILS OF ENTRANCE EXAMINATION

Examination Centre- All India Institute of Medical Sciences Kalyani, West Bengal.

Duration- 02 hours.

Pattern of Questions- Multiple Choice Questions (MCQs).

Medium of Entrance Examination- English.

Total Marks- 100 Marks (Each question carrying ‘1’ mark) and without Negative Marking.

DISTRIBUTION OF NUMBERS

Sl. No.

Subject

Questions

1

Biology

40

2

Physics

20

3

Chemistry

20

4

English

10

5

General Knowledge

10

FEE DETAILS

Fees particulars

Amount to be paid

Time of payment

Remark

Application fees for the entrance examination

Rs. 500/-

Rs. 250/- (For SC/ST)

During the submission of the application

Not refundable

Course fees

Rs. 2000/-

During admission

Not refundable

Caution deposit

Rs. 5000/-

During admission

Refundable on completion/quitting of the course

Final Examination fees

Rs. 500/-

During the Final examination of the course

Not refundable

MODE OF PAYMENT OF APPLICATION FEES

The application fee should be deposited in the following account and the payment receipt should be sent along with the hard copy of the application form.

Title Name

AIIMS Kalyani Internal Resources Account

Account Number

41277688529

Name of the Bank

State Bank of India

Branch

AIIMS Kalyani (Code-63963)

IFSC Code

SBIN0063963

MICR

700002838

ELIGIBILITY

Any Indian citizen who has completed 10+2 standard with science subjects i.e. Biology, Physics, Chemistry and English is eligible to apply for the course. Biology is compulsory among all the subjects to be an eligible candidate.

AGE LIMIT

The age of the candidate should be a minimum of 17 years to a maximum of 30 years however, age should be determined as per the entry in the matriculation or its equivalent certificate. Furthermore, age relaxation can be considered under the following categories:

1 5 years for ‘Physically Challenged’ candidates.

2 5 years relaxation for SC/ST category.

3 3 years relaxation for OBC category.

GENERAL GUIDELINES

1 Interested applicants satisfying the eligibility criteria in all respects may submit their applications along with required documents by post/courier/registered/speed post.

2 Candidates must ensure that the hard copy of their application and self-attested copies of other relevant documents should reach the Institute within 10 days from the last date of application.

3 Signed hard copies of the application along with all certificates/documents should be sent through speed post/courier etc. within the stipulated period, otherwise, the candidature of the applicant will not be considered.

4 Applicants have to paste their passport-size photograph with a cross mark without covering their face.

5 Scanned copies of both the application and payment receipt must also be sent to the website of the AIIMS Kalyani Faculty Exam Section.

The application will be considered invalid in the following situations:

1 If only an online application has been submitted but the hard copy has not been received within the last date.

2 In no case will the application be considered after the last date.

3 Incomplete application form does not have the applicant’s signature.

4 Applications without a passport photograph or photocopied photograph will not be considered.

5 Application forms without required certificates/documents.

6 The Institute does not take any responsibility for any delay or loss of application form or correspondence in postal/courier transit.

7 Any kind of publicity related to any applicant during examination and counselling.

DOCUMENTS

1 10th Standard passing certificate.

2 12th Standard / Higher secondary passing certificate.

3 Caste certificate issued by the appropriate authority (for OBC and EWS candidates the certificate must be within a validity period of one year).

4 Character Certificate issued by the Head of the Institution last attended.

5 The copy of the Aadhaar Card.

The candidate should ensure that the photograph fixed on the application form is recent and not taken more than 6 months before the date of application.

SELECTION PROCEDURE

Admissions will be made strictly in order of merit based on weighted marks i.e. 50% of the total marks in the entrance examination. If more than one candidate has the same marks in the entrance examination, then the selection will be based on:

1 The minimum number of wrong answers attempted.

2 Seniors in age shall be given preference.

However, the decision of the competent authority will be the final decision regarding selection.

IMPORTANT TENTATIVE DATES

Sr.no

Dates

July session

A.

Advertisements to be published on the website

1st March

B.

Submission of Application form & examination fee closure

15th April

C.

Publication of eligibility list

15th May

D.

Conducting entrance examination in collaboration with IT section (date to be fixed each time)

1st week of June

E.

Publication of result on website (date to be fixed each time)

2nd week of June

F.

Submission of course fees & admission (date to be fixed each time)

3rd & 4th week of June

RULES OF ADMISSION

1 The Diploma in Dental Hygienist and Dental Mechanics Courses are full-time courses with two years duration, prescribed and controlled by the Dental Council of India. These courses are conducted at the All India Institute of Medical Sciences, Kalyani. These courses and examinations are conducted in English language.

2 Admission to these courses is open only to Indian Nationals.

3 No stipend and accommodation will be provided by the institution to any candidate.

4 The candidate applying for these courses must have passed the 12th standard / Higher Secondary/ equivalent examination with Biology, Physics, Chemistry & English subjects, from any recognised institution in India.

5 Selection of the candidates will be done strictly based on merit.

6 The candidates belonging to the following backward class categories i.e., SC, ST, OBC, will be required to submit the Xerox copy of the caste validity certificate at the time of submission of documents which will be physically verified at the time of the admission process, failing which the category claimed, will not be granted and the candidate will be treated as a general candidate.

7 The counselling will be done as per the merit list on the scheduled date.

8 Medical check-ups will be done at AIIMS Kalyani before joining the candidates and the medically unfit individuals will not be allowed to join the course.

9 All certificates in original must be produced at the time of admission. If any disparity is found in the original documents admission will be cancelled. Similarly, any request for an extension in the period for submission of the same will not be entertained.

10 The selected candidates will have to give an undertaking in writing to abide by the discipline rules and regulations of the Institution.

11 Details of the tentative Merit List as well as the date of the Interview will be displayed on AIIMS Kalyani’s official website.

12 All the candidates are instructed to visit the AIIMS Kalyani website regularly for any communications and further information. No individual communication will be made.

13 The selected candidate must join the Institution, on or before the date prescribed by the competent authority, failing which his/ her admission stands cancelled.

14 The student while studying in these courses, if found indulging in anti-national activities, unlawful activities or ragging in any form, contrary to the provisions of relevant Acts and Laws enforced by the Government, will be liable to be expelled from the Institution.

To view the official notice, click the link below

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AIIMS Delhi released Time Table for BSc Hons Nursing Phase I, IV Exams 2024

New Delhi- The All India Institute of Medical Sciences (AIIMS) Examination Section has issued a notice detailing the schedule for Phase I and IV (Regular) professional exams for B.Sc Nursing Hons.

The Phase I theory exam is set to take place from the 11th to the 24th of May 2024, while Phase IV will commence from the 6th to the 13th of May 2024. Both exams will start from 2:00 PM to 5:00 PM on the 1st floor of the Examination Section in Convergence Block AIIMS, New Delhi. Meanwhile, candidates are advised to contact either the college or the concerned department for practical exams of Phase I and IV.

SCHEDULE OF PHASE-I

Date

Day

Subject

Paper No.

Venue & Time of Theory

11.05.2024

Saturday

(A) Anatomy (B) Physiology

I

Examination Section
First Floor
Convergence Block
AIIMS, New Delhi

02:00 PM
to
05:00 PM

13.05.2024

Monday

(A) Nutrition (B) Biochemistry

II

15.05.2024

Wednesday

Nursing Foundation

III

20.05.2024

Monday

Psychology

IV

22.05.2024

Wednesday

Microbiology

V

24.05.2024

Friday

English

VI

*

Practical

Nursing Foundation

IX

Dates for Practical Examination
Contact the College of
Nursing/concerned Department.

SCHEDULE OF PHASE-IV

Date

Day

Subject

Paper No.

Venue & Time of Theory

06.05.2024

Monday

Midwifery and Obstetrical Nursing

I

Examination Section
First Floor
Convergence Block
AIIMS, New Delhi

02:00 PM
to
05:00 PM

08.05.2024

Wednesday

Community Health Nursing-II

II

10.05.2024

Friday

Nursing Research & Statistics

III

13.05.2024

Monday

Management of Nursing Services & Education

IV

*

Practical-I

(Midwifery & Obstetrical Nursing)

V

Dates for Practical Examination
Contact the College of
Nursing/concerned Department

Practical-II

Community Health Nursing

VI

IMPORTANT POINTS

1 All the candidates are advised to deposit their examination fee before the last date of registration which will be announced later and take a printout of the admit card from the website.

2 No candidate will be allowed to enter the examination hall without an admit card and identity card.

3 Students are urged to regularly visit the AIIMS Examination Section website “Student Tab” for all the latest information.

To view the official notice, click the link below

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