USA: A recent study published in Diabetes Research and Clinical Practice highlights a significant concern for individuals with type 2 diabetes mellitus (T2DM) who are on long-term metformin therapy. Researchers, led by Aryana Sepassi from the University of California, San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences, report that prolonged metformin use is strongly […]
New research has found that the use of GLP-1 receptor agonists*, a class of medications commonly prescribed for patients with obesity and diabetes, reduces the environmental footprint of healthcare and clinical outcomes when used to treat heart failure. Treatment of heart failure patients with these therapies led to fewer hospitalizations and lower calorie intake, which […]
Inflammatory cardiomyopathy, often following fulminant myocarditis, is characterized by myocardial inflammation, impaired cardiac function, and increased risk of heart failure. Effective management of this condition is essential to prevent long-term complications and improve patient survival. Traditional treatment approaches often focus on supportive care, but recent research has explored immunomodulatory therapies to directly target inflammation and […]
Researchers have found in a phase 3 trial that toripalimab combination therapy without cisplatin proved feasible, offering high failure-free survival and low toxicity in locoregionally advanced nasopharyngeal carcinoma (NPC). This study was published in JAMA by The DIAMOND Study Group. NPC is a cancerous tumor that originates from the nasopharynx and has a high incidence […]
Spain: A large international study led by Dr. Oriol Sibila and colleagues at the Hospital Clinic, University of Barcelona, has shown that the daily symptom burden in bronchiectasis patients is a strong independent predictor of future exacerbations. The findings, published in The Lancet Respiratory Medicine, also suggest that long-term macrolide treatment could benefit patients with […]
New research has found a more effective way to conduct cardiopulmonary resuscitation (CPR) in microgravity,* which causes the weightlessness astronauts experience in space. The study found that a type of automatic chest compression, carried out by a standard mechanical piston device, reached the depth needed to be effective, while the current CPR methods recommended for […]
A new study has identified markers that may predict whether a chlamydia infection is likely to ascend into the uterus and endometrium. The work could lead to new diagnostics that can predict a woman’s risk of severe infection. Chlamydia trachomatis (CT) is a sexually transmitted bacterium that can lead to pelvic inflammatory disease, infertility and […]
Using total-body PET imaging to get a better understanding of long COVID disease is the goal of a new project at the University of California, Davis, in collaboration with UC San Francisco. The project is funded by a grant of $3.2 million over four years from the National Institute of Allergy and Infectious Diseases, part […]
Recent scientific study looked into the use of local anesthetic medications administered directly into the abdominal cavity to manage pain after abdominal surgery. While this method is commonly used, its effectiveness and safety have been unclear. The researchers conducted a systematic review and meta-analysis of various studies to evaluate how well these medications work for […]
China: A large-scale retrospective cohort study published in the American Journal of Ophthalmology has revealed that individuals with low body size in adulthood face a significantly higher risk of developing primary open-angle glaucoma (POAG), a leading cause of irreversible blindness worldwide. The research, led by Jianqi Chen and colleagues from the State Key Laboratory of […]