Entries by aaron

Relief Sought for Small Retailers as GST 2.0 Sparks Losses in Pharma Trade

New Delhi: Noting the fact that the reduction in GST rates (18% to 5%, 12% to 0%, 12% to 5%) has benefited consumers, but it has severely impacted the financial position of small traders, the All India Organisation of Chemists & Druggists (AIOCD), representing over 12.5 lakh chemists and distributors across the country, has appealed […]

MSN Lab gets CDSCO panel nod for Phase IV CT of Tofacitinib Oral Solution

New Delhi: The Subject Expert Committee (SEC) functioning under the Central Drugs Standard Control Organisation (CDSCO) has granted approval to MSN Laboratories to conduct a Phase IV clinical trial of Tofacitinib Oral Solution 1 mg/ml. However, the nod is subject to the condition that the dosing regimen shall be stratified across at least two distinct […]

Health Ministry Bans 34 Key Antibiotics, Antivirals for Animal Use, See List

New Delhi: Through a recent Gazette notification, the Ministry of Health and Family Welfare has notified a ban on the import, manufacture, sale, and distribution of several classes of antimicrobials for animal use, including 15 antibiotics such as carbapenems, ceftobiprole, ceftaroline, glycopeptides and oxazolidinones, 18 antivirals such as favipiravir, molnupiravir, oseltamivir, ribavirin and zanamivir and […]

TyG-BMI may predict Adverse Pregnancy Outcomes in IVF, suggests research

Researchers have found in a new study that higher triglyceride-glucose body mass index (TyG-BMI) was associated with increased miscarriage rates in both fresh and frozen embryo transfer (FET) cycles, along with reduced live birth rates in FET and cumulative live birth outcomes. TyG-BMI may serve as a practical marker to identify patients at higher metabolic […]

Women’s Childbirth Experiences in the WILL Randomised Trial: A Mixed Methods Analysis

Chronic or gestational hypertension complicates 7% of pregnancies, half of which will reach 37 weeks’ gestation. Observational data suggest that early term birth (at 37 to 38 weeks) may reduce maternal complications (e.g., preeclampsia), Caesareans, stillbirth and costs of maternal fetal surveillance; however, early term birth may increase neonatal morbidity. There are no high-quality data […]

Higher levels of air pollution linked to worsening of sleep apnea: ERS Stu

People who have obstructive sleep apnoea (OSA) may suffer worse symptoms if they live in areas with higher levels of air pollution, according to a multi-national study presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands . Patients with OSA often snore loudly, their breathing starts and stops during the night, and […]

Mandibular Devices Effective for Severe Sleep Apnea with Hypertension: Study

Researchers have identified in a new study that mandibular advancement devices (MADs) are a valuable and acceptable treatment for patients with severe obstructive sleep apnea (OSA) and hypertension, offering significant improvements in sleep-related quality of life and blood pressure. Although continuous positive airway pressure (CPAP) is currently the gold standard treatment, this study demonstrates that […]

FDA Approves Palsonify for Acromegaly Treatment

The FDA has approved Palsonify™ (paltusotine) for adults with acromegaly who did not respond adequately to surgery or are not candidates for surgical treatment. PALSONIFY, a selectively-targeted somatostatin receptor type 2 nonpeptide (SST2) agonist, is now the first once-daily, oral treatment approved for adults with acromegaly. “With the FDA approval of our lead therapy Palsonify, […]

Stem cells may offer new hope for end-stage kidney disease treatment, suggests research

More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood. Hemodialysis is a precursor to kidney transplant. To prepare for it, patients typically undergo surgery to connect an artery and a vein in the arm, creating an arteriovenous fistula (AVF) that […]