Entries by aaron

Use of computerized insulin order may improve blood sugar control in hospitalized cardiac patients

Saudi Arabia: A recent study published in Cardiovascular Endocrinology & Metabolism has shed light on the effect of implementing computerized insulin order sets for managing hyperglycemia in hospitalized cardiac patients. The researchers revealed an association between using computerized insulin order sets and potential improvements in fasting and random glycemic control without raising the risk of […]

BMI may independently predict non-calcified plaque presence among patients with a CAC 0: Study

Iraq: The presence of non-calcified plaque in patients with a coronary calcium score of 0 is associated with diabetes mellitus, advanced age, high body mass index (BMI), and increased pericardial fat volume (PFV), a recent study has revealed. The researchers revealed that after multivariate adjustment, increased body mass index remained a significant predictor for the […]

Extended use of inclisiran safe and efficacious among refractory dyslipidemia in patients with increased CV risk

A recent study sheds light on the safety profile of inclisiran, an innovative agent designed to reduce low-density lipoprotein cholesterol (LDL-C). The research aimed to provide comprehensive evidence on the long-term safety of inclisiran, a small interfering RNA agent with promising implications for managing dyslipidemia. This study was published in the Journal Of The American […]

Aficamten improved outcomes for patients with obstructive hypertrophic cardiomyopathy: Phase 3 SEQUOIA-HCM trial

USA: The pivotal Phase 3 clinical trial (SEQUOIA-HCM) of aficamten in patients with symptomatic obstructive hypertrophic cardiomyopathy (HCM) has yielded positive results, as announced by drugmaker Cytokinetics. The top-line results from the SEQUOIA-HCM trial showed that aficamten, a novel cardiac myosin inhibitor, improved outcomes for patients with symptomatic obstructive HCM. The full results from SEQUOIA-HCM […]

Nirsevimab effective in preventing hospitalization for RSV associated lower RTI in infants

Respiratory syncytial virus (RSV) is a common cause of lower respiratory tract infection in young children and infants, leading to hospitalization. According to a study published in the New England Journal of Medicine, Nirsevimab protected infants against hospitalization for RSV-related lower respiratory infections in conditions that approximated real-world settings. The aim of the study was […]

Submit safety, efficacy data of Indian Patients: CDSCO Panel Tells AstraZeneca on additional indication of Enhertu 100mg

New Delhi: In response to the drug major AstraZeneca’s proposal for the additional indication of Trastuzumab Deruxtecan Powder Concentrate Solution for Infusion (Enhertu 100mg) to treat adult patients with unresectable or metastatic Non-small cell lung cancer (NSCLC) whose tumors have activated HER2 (ERBB2) mutations and who have received prior systemic therapy, the Subject Expert Committee […]

Metoclopramide may decrease need for second look Endoscopic Visualization in Active Upper GI Bleeding

In a recent breakthrough study conducted between April 2021 and October 2022, researchers delved into the effectiveness of metoclopramide in improving gastric visualization for patients experiencing active upper gastrointestinal bleeding (UGIB). They found that Metoclopramide did not significantly enhance endoscopic visualization overall but notably reduced the need for a second-look esophagogastroduodenoscopy (EGD) in patients with […]

Delhi Vigilance Dept calls for CBI probe into suspected spurious drugs

The Delhi government’s Directorate of Vigilance has sent the matter of suspected spurious drugs to the Union Home Ministry, urging a thorough investigation by the Central Bureau of Investigation (CBI). The Directorate of Vigilance, in a formal letter to the Union Home Ministry on Thursday, said, “Assigning the matter if reported supply of not of […]

WBCERC has no authority to adjudicate Medical Negligence Cases: Calcutta High Court

Kolkata: In a major decision, the Calcutta High Court bench has clearly iterated that matters concerning the issues of medical negligence cannot be adjudicated by the West Bengal Clinical Establishment Regulatory Commission (WBCERC). Clarifying its stand in this regard, the HC bench comprising Justice Arijit Banerjee and Justice Apurba Sinha Ray noted, “The negligence in […]