In the industrialized world, Neovascular age-related macular degeneration (AMD) and diabetic macular edema (DME) cause blindness. Faricimab, launched in the US in January 2022, treats diabetic macular edema and wet age-related macular degeneration. Based on evidence from Systematic reviews, anti-VEGF agents’ are advantageous in AMD and DME compared to other therapies. In a study published […]
USA: A recent study published in Fertility and Sterility has shown reduced odds of ovulation with ovulation induction (OI) with clomiphene, metformin, and clomiphene+metformin with a higher Anti-Müllerian hormone (AMH) concentration in women with polycystic ovary syndrome (PCOS) and infertility. “Higher baseline AMH concentrations were associated with a 10% reduction in the odds of ovulation […]
A recent pilot study conducted in Mexican children with asthma suggests that doxofylline, when used in conjunction with inhaled corticosteroids (ICS), may offer a potential steroid-sparing effect. This study was published in the Journal Of Asthma by Sandra Diaz. and colleagues. The study, a 10-week open-label crossover trial, aimed to evaluate the efficacy of doxofylline […]
USA: SGLT2 inhibitors should not be discontinued in response to an initial decline in the estimated glomerular filtration rate (eGFR) among patients with heart failure and mildly reduced ejection fraction (HFmrEF) or preserved ejection fraction (HFpEF), a recent study has suggested. The findings from the prespecified secondary analysis of the DELIVER randomized clinical trial were […]
USA: A recent study published in JAMA Pediatrics has shed light on the diagnostic accuracy of a large language model (LLM) in pediatric case studies. The researchers found that a LLM-based chatbot gave the wrong diagnosis for the majority of pediatric cases. They showed that the ChatGPT version 3.5 reached an incorrect diagnosis in 83 […]
Among obese individuals, elevated liver enzyme levels tied to risk for incident type 2 diabetes suggests a new study published in the Acta Diabetologic The role of liver steatosis and increased liver enzymes (ALT) in increasing incident type 2 diabetes mellitus (T2DM) is debated, because of their differential effects on different ethnicities and populations. The […]
In a recent randomized controlled trial, researchers investigated the potential effect of the Dietary approaches to stop hypertension (DASH) diet in managing non-alcoholic fatty liver disease (NAFLD). The findings were published online in the European Journal of Nutrition on October 19, 2023. The study’s findings demonstrated that adhering to the DASH diet results in significant […]
In a recent study published in The Journal of Dermatology uncovered a significant association between psoriasis, a chronic skin condition, and an increased risk of urolithiasis (kidney stones). The study involved a prospective analysis of a total of 67 psoriasis patients (PS group) and 65 individuals without psoriasis (NPS group) that aimed to explore potential […]
UK: A recent study published in the Journal of Affective Disorders has found a significantly lower prevalence of major depression (4.6%) amongst users of oral contraceptive pills (OCP), compared to former OCP users (11.4%). The research, which analysed data from 6,239 women in the United States aged 18-55 years old, showed that women who are […]
New Delhi: The newly notified Post-Graduate Medical Education Regulations (PGMER) 2023 has specified that post-graduate medical students will get a minimum of 20 days of paid leave (casual leave) per year. Apart from this, under these new regulations, doctors will also be allowed weekly holidays. Further, they will be given maternity leave and paternity leaves as […]