Entries by aaron

Oral Minocycline fails to arrest progression of Macular Degeneration: JAMA

A recent study published in the Journal of American Medical Association investigated the potential of oral minocycline in slowing down the progression of geographic atrophy (GA) in age-related macular degeneration (AMD). GA is a leading cause of irreversible vision loss among the elderly which makes effective treatments crucial. Existing therapies for GA enlargement in AMD […]

Guselkumab improves physical function in patients with active psoriatic arthritis: Study

A recent study published in the ACR Open Rheumatology journal explored the effectiveness of guselkumab in treating patients with psoriatic arthritis (PsA). The study evaluated patient-reported outcomes after 6 months of on-label guselkumab use and provided valuable insights into its real-world effectiveness. Psoriatic arthritis is a chronic inflammatory disease that affects the joints and skin that […]

Omega 3 may arrest memory dysfunction due to high-fat diet intake before surgery: Study

USA: Consuming a high-fat diet can increase the risk of persistent postoperative cognitive dysfunction-associated memory impairments following surgery in a TLR4-dependent manner, a recent study published in Brain, Behavior, and Immunity has found.  The study, building upon previous research from the same lab at Ohio State University, also showed that taking a DHA omega-3 fatty […]

CDSCO Panel Rejects Akum Pharma’s Clonazepam-Duloxetine Combination Drug

New Delhi: Reviewing the justification provided by the drug major Akum Pharmaceutical concerning the fixed-dose combination (FDC) Clonazepam plus Duloxetine Hydrochloride, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has rejected approval for the proposed FDC. This came after the drug maker Akum Pharmaceutical presented the proposal along with justification […]

Zydus Lifesciences gets USFDA okay for Finasteride and Tadalafil Capsules

Ahmedabad: Zydus Lifesciences Limited has announced that the Company has received final approval from the United States Food and Drug Administration (USFDA) to market Finasteride and Tadalafil Capsules USP 5 mg/5 mg. (USRLD: ENTADFI TM). “Zydus is the “first approved applicant” for Finasteride and Tadalafil Capsules, 5 mg/5 mg, as defined in section 505(j)(5)(B)(v)(III) of the […]

Smoking associated with lower coronary volume-to-myocardial mass ratio, study shows

Canada: A recent study published in Radiology: Cardiothoracic Imaging has suggested that current and former smoking status are independently associated with low coronary volume-to-myocardial mass ratio (V/M) on CT fractional flow reserve (CT-FFR). “Smoking is associated with lower coronary volume-to-myocardial mass ratio in individuals with coronary artery disease (CAD),” the researchers reported. The findings further […]

Tooth agenesis tied to early-onset cancer in early childhood and early adulthood: JAMA

Denmark: A recent study published in JAMA Network Open has suggested an association between tooth agenesis and specific cancer types, specifically in childhood and early adulthood. “Our population-based cohort study of 2.5 million live-born singletons with up to 40 years of follow-up showed that tooth agenesis was positively associated with several cancer types, including nephroblastoma, […]