Obesity is a major public health concern, as it is known to increase the risk of dependency and limit mobility in adults. Further over the past decade, obesity rates have skyrocketed worldwide. Excess body weight is known to affect gait, but the influence of body fat distribution on gait parameters and neuromuscular adaptations remains unclear. […]
An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy (GAN), was well tolerated and showed signs of therapeutic benefit in a clinical trial led by the National Institutes of Health (NIH). Currently, there is no treatment for GAN and the disease is usually fatal by […]
Australia: Hyperglycemia increases the risk of in-hospital healthcare-associated infection (HAI), acute kidney injury (AKI), and stroke compared with those not experiencing hyperglycemia in hospital inpatients (HbA1c ≤ 12.0%), a recent study has shown. The risk was observed regardless of the patient’s diabetes status and pre-hospital glycaemia. The study was published online in The Journal of […]
USA: Researchers at the University of California San Diego School of Medicine have uncovered a noninvasive approach that can be used to better predict the quality of lab-grown embryos. The new method works by detecting small particles of genetic material, called exRNAs, that are left behind in the liquid media young embryos are grown in. […]
USA: The US Food and Drug Administration (FDA) has approved aprocitentan (Tryvio) for treating hypertension in combination with other antihypertensive drugs to lower blood pressure in adult patients not adequately controlled by other drugs. The announcement by Idorsia Pharmaceuticals makes aprocitentan the first endothelin receptor antagonist for treating high blood pressure (BP). Lowering BP reduces […]
Vitiligo is a chronic autoimmune disease that results from the loss of melanocytes, leading to disfiguring skin lesions. This skin condition causes anxiety and depression, and treatment aims to halt the disease progression, and repigment affected areas. Topical medications and NB-UVB phototherapy are typically used, but in some cases, these treatments may not be effective. […]
Researchers have found in a new study that COVID-19 Virus-induced acute Respiratory Distress Syndrome may cause cardiomyopathy through eliciting Inflammatory Responses in the heart. SARS-CoV-2, the virus that causes COVID-19, can damage the heart even without directly infecting the heart tissue, a National Institutes of Health-supported study has found. The research, published in the journal […]
Canada: Colchicine, 0.5 mg daily, leads to a large reduction in cardiovascular (CV) events among patients with type 2 diabetes (T2D) and a recent myocardial infarction (MI), new data from the COLCOT trial has shown. The findings, published in Diabetes Care, offer further insight into the risks associated with and benefits of low-dose colchicine as […]
A recent study published in the Respiratory Research found that computed tomography (CT) scans can play an important role in precise distinction between transudative and exudative pleural effusions. Pleural effusion is a common diagnostic challenge in clinical settings and so, this study conducted a comprehensive two-center retrospective analysis analyzed the diagnostic value of thoracic CT […]
Previous research has identified genetic variants linked to sedentary leisure behavior, which includes activities such as watching television, using a computer, and operating a vehicle. In a new analysis published in Andrology, a higher genetic susceptibility to leisure computer usage was associated with a greater risk of erectile dysfunction in men. In the analysis of […]