Author Archive for: aaronm23@mitash.com
Entries by aaron
FDA okays pemivibart to prevent COVID-19 in immunocompromised patients
Food and Drug Administration (FDA) has granted emergency use authorization (EUA) for monoclonal antibody pemivibart to prevent COVID-19 in immunocompromised patients. Invivyd, Inc. (Nasdaq: IVVD), a biopharmaceutical company today announced that PEMGARDA™ (pemivibart), formerly VYD222, a half-life extended monoclonal antibody (mAb), has received emergency use authorization (EUA) from the U.S. Food and Drug Administration (FDA) […]
RaDPi-U, Promising fast and convenient technique for screening drugs in urine samples, reveals study
Drugs, both legal and illegal, cause millions of cases of severe intoxication every year, leading to health complications and even fatalities. Often, they are also implicated in violent and sexual harassment crimes, as well as accidents. Obtaining detailed information about the drugs consumed by a criminal or victim is often challenging. Forensic professionals rely on […]
SGLT2i-associated ketoacidosis patients receive significantly lower insulin doses vs those with T1D ketoacidosis: JAMA
Australia: A new retrospective cohort study revealed a clinically relevant reduction in the doses of insulin administered over the first 24 hours of treatment in patients with SGLT2 inhibitor-associated diabetic ketoacidosis (DKA) compared with patients with type 1 diabetes DKA. There seems no clarity on whether the protracted duration of SGLT2 inhibitor DKA is a […]
Tobacco exposure early in life can increase risk of development of diabetes later: Study
China: A new study shows a strong correlation between tobacco exposure early in life, whether in the womb or during childhood and adolescence and type 2 diabetes (T2D) development later in life. The large-scale observational analysis extracted records of about 476,000 adults in the UK Biobank. Researchers report that people with preexisting genetic factors for […]
Higher supplemental oxygenation levels not better for COVID-19 patients experiencing hypoxia : JAMA
Higher supplemental oxygenation levels are not better for COVID-19 patients experiencing hypoxia suggests a new study published in the JAMA. Supplemental oxygen is ubiquitously used in patients with COVID-19 and severe hypoxemia, but a lower dose may be beneficial. A study was done to assess the effects of targeting a Pao2 of 60 mm Hg […]
Next-generation stool DNA test may improve sensitivity for colorectal cancer detection: NEJM
Colorectal cancer remains a leading cause of cancer-related mortality worldwide, highlighting the crucial need for effective screening strategies. A recent study unveiled the next-generation multitarget stool DNA test which is more effective in colorectal cancer screening. This innovative screening tool combines assessments of DNA molecular markers and hemoglobin levels to enhance specificity and accuracy in […]
Tirzepatide consistently reduces bodyweight regardless of BMI before treatment, shows new analysis
Tirzepatide, a medication authorised to treat obesity and/or type 2 diabetes, consistently reduces bodyweight regardless of the patient’s body mass index (BMI before treatment), from the range of overweight to class III obesity. The study, to be presented at this year’s European Congress on Obesity (Venice, Italy, 12-15 May) is by Prof Carel Le Roux, […]
Multicomponent intervention may improve health-related quality of life among women with moderate to severe OAB: JAMA
Overactive bladder (OAB) is a common condition affecting women, often leading to decreased quality of life. While cognitive components are recognized in behavioral therapy for OAB, there’s a lack of studies evaluating the effectiveness of multicomponent interventions. A recent clinical trial conducted in Japan evaluated the effectiveness of a multicomponent intervention in improving health-related quality […]
Sexual Dysfunction Common after Successful treatment of Ruptured Aneurysms: Study
A recent study published in Neurology India suggests that in cases of aneurysmal subarachnoid hemorrhage, sexual dysfunctions are common even after good clinical outcomes. Sexual well-being is a fundamental requisite of happiness. The symptoms of sexual dysfunctions (SD) may be subtle or overt. The social stigma attached to this problem in conservative societies has kept […]