Entries by aaron

3D elastography displays better performance in differentiating benign and malignant breast lesions

Ultrasound imaging is an alternative option for breast cancer detection, especially for women with dense breasts. However, using hand-held transducers makes screening dependent on the operator and time-consuming, leading to increased costs. Automated breast volume scanners (ABVSs) were introduced to address this issue. ABVSs use a large linear transducer to acquire ultrasound data and reconstruct […]

Cholesterol-lowering therapy could help prevent and treat serrated-type colorectal tumours

USA: A recent preclinical study from researchers at Weill Cornell Medicine points to the possibility of using cholesterol-lowering drugs to prevent or treat hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumours that develop from them.  According to the study, published in Nature Communications, such tumors depend heavily on the ramped-up production […]

Pitolisant effectively reduces daytime sleepiness among patients of sleep apnea

A recent study published in the CHEST Journal unveiled promising long-term effects of Pitolisant in curbing excessive daytime sleepiness. Even in patients adhering to the standard continuous positive airway pressure (CPAP) therapy, daytime drowsiness can persist, posing a significant challenge to effective obstructive sleep apnea (OSA) management. Initial outcomes of two 12-week randomized controlled trials (HAROSA […]

Tirzepatide may reduce CVD Risk in Non-Diabetic Overweight Patients

The outcomes from the SURMOUNT-1 phase 3 trial found tirzepatide to effectively manage the long-term risk of atherosclerotic cardiovascular disease (ASCVD) among individuals with obesity or overweight but with no diabetes. The findings were published in the Journal of Diabetes, Obesity and Metabolism. The study assessed the efficacy and safety of tirzepatide in adults with […]

Study finds no Direct Association Between Cholesterol Intake and Chronic Kidney Disease Risk

A recent investigation exploring the link between cholesterol intake and the risk of chronic kidney disease (CKD) has yielded intriguing insights, suggesting a nuanced relationship between dietary cholesterol and CKD risk. This study was published in the journal of Nutrition Metabolism and Cardiovascular Diseases by Haekyung Lee and colleagues. The study, utilizing data from the […]

Modify Phase IV CT protocol: CDSCO Panel Tells Alkem on Amoxicillin, Clavulanate Oral Suspension

New Delhi: The Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has opined the drug major Alkem Pharmaceutical to modify the Phase IV clinical trial protocol of the fixed-dose combination (FDC) drug Amoxicillin plus Clavulanate Potassium oral suspension in accordance with the Inclusion criteria, dose of the Potassium Clavulanate, sites […]