USA: A recent preclinical study from researchers at Weill Cornell Medicine points to the possibility of using cholesterol-lowering drugs to prevent or treat hard-to-detect colorectal pre-cancerous lesions known as serrated polyps, and the aggressive tumours that develop from them. According to the study, published in Nature Communications, such tumors depend heavily on the ramped-up production […]
A recent study published in the CHEST Journal unveiled promising long-term effects of Pitolisant in curbing excessive daytime sleepiness. Even in patients adhering to the standard continuous positive airway pressure (CPAP) therapy, daytime drowsiness can persist, posing a significant challenge to effective obstructive sleep apnea (OSA) management. Initial outcomes of two 12-week randomized controlled trials (HAROSA […]
Japan: Masahiro Katamine et and colleagues, in a recent study, said that higher BMI is linked to a higher prevalence of TCFA in younger type 2 diabetes (T2D) patients with a history of coronary artery disease (CAD), especially those who have HbA1c ≥7.0%. This study was published in Nutrition Metabolism and Cardiovascular Diseases. The relationship […]
The outcomes from the SURMOUNT-1 phase 3 trial found tirzepatide to effectively manage the long-term risk of atherosclerotic cardiovascular disease (ASCVD) among individuals with obesity or overweight but with no diabetes. The findings were published in the Journal of Diabetes, Obesity and Metabolism. The study assessed the efficacy and safety of tirzepatide in adults with […]
China: A population-based study revealed that the slow-to-moderate, but not fast, rate of weight loss induced by antiobesity medications is linked with lower all-cause mortality in patients with obesity or overweight and knee or hip osteoarthritis (OA). The findings were published online in Arthritis & Rheumatology on December 6, 2023. “For people overweight or with […]
In a new study of more than 50,000 Korean adolescents, those who used a smartphone for more than 4 hours per day had higher rates of adverse mental health and substance use. Jin-Hwa Moon and Jong Ho Cha of Hanyang University Medical Center, Korea, and colleagues present these findings in the open-access journal PLOS ONE […]
A recent investigation exploring the link between cholesterol intake and the risk of chronic kidney disease (CKD) has yielded intriguing insights, suggesting a nuanced relationship between dietary cholesterol and CKD risk. This study was published in the journal of Nutrition Metabolism and Cardiovascular Diseases by Haekyung Lee and colleagues. The study, utilizing data from the […]
New Delhi: The Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has opined the drug major Alkem Pharmaceutical to modify the Phase IV clinical trial protocol of the fixed-dose combination (FDC) drug Amoxicillin plus Clavulanate Potassium oral suspension in accordance with the Inclusion criteria, dose of the Potassium Clavulanate, sites […]
New Delhi: In response to the proposal presented by the drug major Pfizer for the protocol amendment, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has recommended the firm to submit the justification and rationale for the proposed amendment of the anti-cancer drug Palbociclib. This came after the firm […]
Sanofi India Limited (SIL) has announced the appointment of Himanshu Bakshi as General Manager for its Consumer Healthcare (CHC) business, effective 15th January 2024. SIL earlier this year had announced that the Company’s Consumer Healthcare business will be demerged into its wholly owned subsidiary, Sanofi Consumer Healthcare India Limited (SCHIL), subject to necessary approvals and […]