Graduate Pharmacy Aptitude Test- GPAT 2024 Results OUT

New Delhi- The National Board of Examination Medical Sciences (NBEMS) has released the result of the Graduate Pharmacy Aptitude Test (GPAT) 2024 today.

The result of GPAT-2024 indicating the scores obtained by the candidates and GPAT-2024 Rank has been declared and can be seen at NBEMS’s official website. The individual scorecards of candidates who appeared in GPAT-2024 can be downloaded from the official website of NBEMS on or after July 14, 2024.

GPAT 2024 is a national-level examination for the award of scholarships to qualified candidates seeking entry into the Master of Pharmacy (M. Pharm) course. Appearance in GPAT-2024 does not confer any automatic rights to secure an M. Pharm seat and/or award of scholarship for M. Pharm Courses.

GPAT 2024 is being conducted by NBEMS on June 8, 2024, for admission to Master of Pharmacy Courses/award of scholarship for M. Pharm Courses, on a computer-based platform at various testing centres across the country.

In this regard, NBEMS has issued a notice that stated that the GPAT 2024 rank is the overall merit position of the candidate amongst all the candidates who have appeared in the examination. In case of two or more candidates obtaining equal scores in GPAT-2024, the inter-se-merit of such candidates will be determined.

Further, the final answer keys of GPAT-2024 have been prepared based on the inputs of the subject matter experts after examining all the challenges/objections raised by the candidates to the provisional answer keys/recorded responses of GPAT 2024. Meanwhile, as per the inputs of the experts, 3 questions were found to be technically incorrect. However, full marks have been awarded to all the appeared candidates whether they have attempted these 3 questions or not.

Also Read: GPAT 2024: NBE To Close Pre-Final Edit Window Today

As per the notice, technically incorrect questions were found in two subjects in GPAT-2024 namely 1 in Pharmaceutical Chemistry and Allied Subjects and 2 in Pharmaceutics and Allied Subjects.

With this, it has been informed that the validity of the scorecard of GPAT-2024 will be for three years. Meanwhile, if at any stage, candidates are found to have resorted to the use of any unfair means in the exam, such candidates shall be liable for penal action. Action as deemed appropriate by NBEMS will be taken against the candidates.

Also Read: GPAT 2024: NBE issues corrigendum On Information Bulletin, Details

Admission to M. Pharm courses is undertaken by the State Government/State Admission Committee. NBEMS has no role whatsoever in the conduct of counselling for admission to M. Pharm/PhD courses utilizing GPAT score/award of scholarship for M. Pharm Courses. Candidates must apply separately to the desired GPAT-2024 Participating Institutions. Thereafter, each Participating Institute will release its respective cut-off GPAT Scores which a candidate should meet to qualify for admission to that particular Institution.

NBEMS has no role in counselling and disbursement of scholarships. However, verification of documents and eligibility determination of the candidates will be undertaken at the time of the counselling/admission process by the concerned authority.

To view the notice, click the link below

https://medicaldialogues.in/pdf_upload/graduate-pharmacy-aptitude-test-2024-results-outjpg-243385.pdf

Powered by WPeMatico

Air pollution linked to a decrease in IVF birth rate success, new study shows

A pioneering study, presented at the ESHRE 40th Annual Meeting in Amsterdam, has revealed that exposure to fine particulate matter (PM) prior to the retrieval of oocytes (eggs) during in vitro fertilization (IVF) can reduce the odds of achieving a live birth by almost 40%.

Powered by WPeMatico

Gestational carriers face higher health risks during pregnancy compared to IVF and natural conceptions, study shows

Gestational carriers, also known as surrogates, experience an elevated risk of severe maternal morbidity and adverse pregnancy outcomes compared to women who conceive naturally or through in vitro fertilization (IVF), according to research presented at the ESHRE 40th Annual Meeting in Amsterdam.

Powered by WPeMatico

Novel treatment improves embryo implantation and live birth rates in infertile women undergoing IVF and ICSI

New research has demonstrated the effectiveness of a first-in-class oral, non-hormonal drug in increasing embryo implantation, pregnancy and live birth rates among infertile women who are undergoing in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI).

Powered by WPeMatico

Federal WIC program may boost pregnancy outcomes for women, newborns

Pregnant women enrolled in a federal aid program have better outcomes than those who are struggling to put food on the table, new research shows.

Powered by WPeMatico

Daydream a lot? Feel sluggish? Stare into space? You might have cognitive disengagement syndrome

Do you find that you daydream a lot? Are you often sluggish and tend to disengage easily when doing a task? You might have cognitive disengagement syndrome, or CDS.

Powered by WPeMatico

Understanding Post Meal Reflux and Benefits of Sodium Alginate – Dr Shubham Vatsya

Post meal reflux refers to the phenomenon where patients experience severe burning in the middle of the chest shortly after eating. This discomfort arises due to dysfunction in the lower esophageal sphincter (LES), a structure at the junction of the esophagus and stomach. Traditional treatments like proton pump inhibitors and H2 receptor antagonists reduce stomach acid but don’t address reflux directly. In contrast, sodium alginate, a barrier compound, offers a mechanical solution. It forms a protective raft atop stomach contents, preventing acid from reaching the esophagus.

In this insightful video Dr Shubham Vatsya, a renowned Gastroenterologist from Fortis Hospital, Vasant Kunj, Delhi explains about What is post meal reflux and how to clinically suspect it? And What are the clinical benefits of Sodium Alginate in the management of post meal reflux. He discusses the distinctive symptoms that characterize this condition, such as severe chest burning occurring shortly after eating, which stem from dysfunction in the lower esophageal sphincter (LES) at the junction of the esophagus and stomach. He explores how patients often experience discomfort and elucidates on the therapeutic benefits of sodium alginate in managing post meal reflux. Unlike traditional acid-reducing medications, sodium alginate acts as a mechanical barrier

Powered by WPeMatico

SCB Medical College Struggles to Digitize Patient Records

Cuttack: The Medical Record
Department at SCB Medical College and Hospital (SCB MCH) remains in disarray as
it awaits digitization—a promise made three years ago. The department houses
thousands of patient records, some dating back over four decades, in a largely
unorganized manner. Despite the pressing need for modernizing this crucial
aspect of healthcare management, the process has yet to commence.

The department’s vast
collection of paper records includes documents that have been carelessly
stacked, creating significant challenges in retrieving essential information.
Historical mismanagement has compounded the issue. The 1999 Super Cyclone
inflicted severe damage, destroying numerous critical documents. More recently,
a fire in April 2019 further devastated the archive, turning many invaluable
records to ashes, reports the Daily. 

Also Read:Grave Medical Negligence by AYUSH Doctor: NHRC Directs Odisha Govt to Pay Rs 4 L Compensation to Woman

The current state of the
department not only hampers the hospital’s operational efficiency but also
causes frustration for patients, police, and hospital staff who struggle to
locate essential medical histories amidst the voluminous paperwork.

Recognizing the dire need
for improvement, SCB MCH authorities submitted a formal request to the Health
and Family Welfare Department in September 2021, advocating for the
digitization of the medical record department. The aim was to streamline access
to patient records, enhance data security, and improve overall service
delivery. However, despite the submission, no action has been taken to date.

A retired hospital staff told The New Indian Express, “It
is a matter of concern that the state government is not initiating any steps to
digitize the record room of SCB MCH even till now. Once digitized, it will be
helpful in preserving important documents without any hassle and save a lot of
time. Besides, they can be accessed with just a click.”

Also Read:Medical negligence complaint cannot be entertained without opinion of another doctor: Jharkhand HC relief to doctor

Health and Family Welfare
Minister Mukesh Mahaling recently visited SCB Medical College and underscored
the importance of transitioning to a paperless system. He highlighted the need
for online accessibility of patient records, which would save time and ensure the safety and longevity of crucial health data.

The continued reliance on
physical records not only impedes efficient healthcare delivery but also poses
significant risks, as evidenced by past disasters. With the current
technological advancements and the growing need for quick and reliable access
to patient information, digitizing medical records is a critical step forward.
The call for action from Minister Mahaling is a hopeful sign, but the
implementation of such a system remains crucial.

Powered by WPeMatico

Isotretinoin Shows Promise for Acne in Transgender and Gender-Diverse Individuals on Masculinizing Hormone Therapy: JAMA

USA: In a groundbreaking study published in the JAMA Dermatology, researchers have shed light on the efficacy and safety of isotretinoin treatment for acne in transgender and gender-diverse individuals undergoing masculinizing hormone therapy. This research represents a significant step towards addressing a longstanding gap in dermatological care for this population.

The case series study of 55 transgender and gender-diverse individuals with acne who were receiving gender-affirming hormonal therapy revealed that treatment with isotretinoin was associated with clearance in 63.6% and improvement in 97.0% of patients treated with a cumulative dose of 120 mg/kg or more. However, premature treatment discontinuation was common and tied to poorer outcomes.

Acne is a common concern for individuals undergoing hormone therapy as part of their gender transition. Masculinizing hormone therapy, which typically involves the use of testosterone, can lead to an increase in sebum production, resulting in acne flare-ups. However, concerns about potential interactions between isotretinoin and hormone therapy have limited its use in this population.

While isotretinoin is a highly effective acne treatment, not much is known about its safety and effectiveness among transgender and gender-diverse individuals receiving gender-affirming hormonal therapy. James Choe, Harvard Medical School, Boston, Massachusetts, and colleagues aimed to evaluate clinical outcomes of isotretinoin among transgender and gender-diverse individuals receiving gender-affirming hormonal therapy.

For this purpose, the researchers conducted a multicenter retrospective case series study at four medical centers: the University of Pennsylvania, Mass General Brigham, Fenway Health, and Emory University. It included patients aged 12 to 49 years who were receiving masculinizing gender-affirming hormonal therapy and prescribed isotretinoin for the management of acne between 2015 and 2023.

The outcomes were the percentage of patients experiencing clearance or improvement of acne, and rates of acne recurrence. The researchers also evaluated adverse effects and reasons for treatment discontinuation.

The study led to the following findings:

  • Among 55 included patients, the mean age was 25.4 years; 7.3% were Asian, 2 3.6% were Black, 7.2% were Hispanic, 1.8% multiracial, and 65.5% were White. The median isotretinoin course duration was 6 months, with a median cumulative dose of 132.7 mg/kg; the cumulative dose was less than 90 mg/kg for 29.1% of patients and less than 120 mg/kg for 40.0%.
  • Isotretinoin was associated with improvement in 87.3% and clearance in 47.3% of patients.
  • For the 33 patients treated with a cumulative dose of 120 mg/kg or more, these rates increased to 97.0% and 63.6% of patients, respectively.
  • Among the 20 patients who achieved acne clearance and had any subsequent healthcare encounters, the risk of recurrence was 20.0%.
  • The most frequently reported adverse effects were dryness (80.0%), joint pain (14.5%), and eczema (9.1%).
  • Laboratory abnormalities were uncommon.
  • Reasons for premature treatment discontinuation included cost, pharmacy issues, adverse effects, logistical reasons (scheduling), and wound healing concerns for gender-affirming surgery.

In the case series study of patients with acne who were receiving masculinizing gender-affirming hormonal therapy and underwent isotretinoin treatment, isotretinoin was often effective and well tolerated. However, premature treatment discontinuation was common and tied to poorer outcomes.

“There is a need for further efforts to understand optimal dosing and treatment barriers to improve outcomes in transgender and gender-diverse individuals receiving masculinizing gender-affirming hormonal therapy,” the researchers concluded.

Reference:

Choe J, Shields A, Ferreira A, et al. Isotretinoin for Acne in Transgender and Gender-Diverse Individuals Receiving Masculinizing Hormone Therapy. JAMA Dermatol. Published online May 29, 2024. doi:10.1001/jamadermatol.2024.1420

Powered by WPeMatico

21 newborn deaths reported at Thane’s Kalwa Hospital in June, Probe ordered

Thane: The government-run Chhatrapati Shivaji Maharaj Hospital, Kalwa in Thane district has once again come under the spotlight due to the controversy surrounding the shocking number of deaths of newborns. It has been reported that 21 newborns passed away in the Neonatal Intensive Care Unit (NICU) in June of this year. 

The exact number of confirmed newborn deaths was provided by the Hospital dean, Dr Rakesh Barot to Free Press Journal. According to the dean, among the 21 newborns, some were referred to this hospital in critical condition from a private hospital and therefore he claimed that the numbers were not alarming. 

Child Specialist Dr Jayesh Panot told ANI, “15 babies were born in the hospital here and 6 were referred here. When we analyse the causes of the deaths, we find low birth weight and pre-term delivery as the two main reasons.”

Also read- 18 Patients Die At Chhatrapati Shivaji Maharaj Hospital In 24 Hours, Probe Ordered

According to the data shared by the hospital authorities reported by ABP, In January 2024, 17 newborns passed away, followed by 10 in February, 22 in March, 24 in April, 16 in May, and 21 in June of the same year, totalling 89 infant deaths. The hospital reported that out of the 512 deliveries in June, 90 newborns were in critical condition, with 21 of them could not survive. 

Additionally, 19 babies were born underweight, 15 were premature, and 6 were delivered outside the hospital. Unfortunately, three of the babies born outside the hospital died before they could be admitted. Furthermore, 13 newborns weighed less than 1.5 kg, with 3 of them weighing less than 1 kg. The hospital mentioned that some of these infants passed away within 48 hours of birth, as per the daily report. 

Meanwhile, TOI reports that the hospital recorded 110 infant deaths in the last six months between Jan and June this year. However, the number of infant deaths in July is presently unavailable. 

When contacted, the Head of the paediatric department Dr Jayesh Panot told FPJ, “Most of the children concerned were the ones who did not receive treatment in the golden minute, which is the minute just after birth. By the time the kids are admitted to our hospital, precious time has already been lost and there is little that can be done medically to save them.”

Medical Dialogues team in August 2023 reported the deaths of 18 patients in the last 24 hours and two doctors were suspended for dereliction of duty.

After that, Chief Minister Eknath Shinde visited the hospital and instructed the hospital authorities to provide facilities in the hospital. However, the relatives of the patients are still complaining about the lack of facilities in the hospital.

This issue was raised in the Maharashtra Legislative Assembly on Friday after it gained the attention of the Congress MLA Amin Patel. Based on the report presented at the assembly by Patel, State Minister Uday Samant assured that an inquiry would be made and a statement would be made in the House within two days.

In a post on X, Patel asked, “Who is responsible for these deaths? Government? The administration? Hospital? Doctors say newborn babies couldn’t get essential medicines immediately after birth, causing their death. The health minister of the state should take immediate action against this and take steps to prevent such incidents.”

Also read- Thane Hospital Deaths Case: 2 Doctors Suspended For Dereliction Of Duty

Powered by WPeMatico