Keto diet metabolite may power up CAR T cells to kill cancer

A simple dietary supplement may provide a new approach to boost CAR T cell function, according to a study by researchers in the Perelman School of Medicine at the University of Pennsylvania and Penn Medicine’s Abramson Cancer Center. While the approach needs to be assessed in clinical trials, the early research, shared in a press briefing at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition, hints at a potentially cost-effective strategy to improve CAR T cell function and cancer-fighting abilities.

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