Entries by aaron

No significant interaction between treatment strategy with intravascular imaging-guided PCI and sex: JAMA

Korea: A subgroup analysis of the RENOVATE-COMPLEX-PCI trial including 1639 patients showed no significant interaction between treatment strategy and sex in patients undergoing complex PCI with the treatment benefit of intravascular imaging–guided PCI. “In the analysis, intravascular imaging guidance was associated with reducing the risk of target vessel failure in both women and men,” the […]

Merck begins phase 3 trial of MK-1084, Keytruda combo for first-line treatment of certain patients with Metastatic Non-Small Cell Lung Cancer

Rahway: Merck, known as MSD outside of the United States and Canada, has announced it has initiated a Phase 3 clinical trial evaluating MK-1084, an investigational oral selective KRAS G12C inhibitor, in combination with KEYTRUDA for the first-line treatment of certain patients with metastatic non-small cell lung cancer (NSCLC) whose tumors harbor KRAS G12C mutations and […]

Statins associated with new-onset diabetes in dose-dependent manner: Lancet

USA: A meta-analysis of individual participant data has shed light on the effects of statin therapy on diagnoses of new-onset diabetes and worsening glycemia in large-scale randomized blinded statin trials. The study findings, The Lancet Diabetes & Endocrinology, reaffirm a dose-dependent association between statin therapy, which may be relevant for guidelines and shared decision-making. However, […]

KGMU Trauma Centre to get pneumatic tube conveyor system for transporting samples

Lucknow: The trauma centre at King George’s Medical University (KGMU) is set for a significant upgrade with the introduction of a pneumatic tube conveyor network system.  This innovative system is designed to revolutionize the transportation of blood samples and other specimens between wards and the laboratory, promising to drastically reduce time and effort.  Vice-chancellor Soniya Nityanand […]

Novel lateral flow assay rapid and cost-effective point-of-care test for diagnosis of Neisseria gonorrhoeae: Lancet

Effective control of Neisseria gonorrhoeae (N. gonorrhoeae) relies on rapid and accurate diagnostic tests. The World Health Organization (WHO) and Foundation for Innovative New Diagnostics (FIND) have established criteria for a non-molecular rapid point-of-care test, emphasizing the need for high sensitivity and specificity, quick turnaround time, and affordability. A novel lateral flow assay (NG-LFA) has […]

Bariatric artery embolization may improve weight loss in obesity patients, claims study

A recent clinical trial named BEATLES showed the potential of the procedure known as bariatric arterial embolization (BAE) using novel, custom-engineered radiopaque microspheres, BTG-001933 that was developed by Boston Scientific. The key findings of this study were presented in the SIRpass summit and the abstract was published in the Journal of Vascular and Interventional Radiology […]

Long-term progesterone use increase intracranial meningioma risk in women: BMJ

A comprehensive national case-control study conducted in France revealed a significant link between the use of specific progestogen-based medications and a higher risk of developing intracranial meningioma. The key findings were published in the British Medical Journal. This research utilized data from the French National Health Data System and scrutinized the health records of over […]

Preheated thermoviscous composite resin useful option for restoring noncarious cervical lesions restorations: Study

Preheated thermoviscous composite resin useful option for restoring noncarious cervical lesions restorations suggests a new study published in the Journal of Dentistry. This 24-month, double-blind, split-mouth randomized clinical trial aimed to compare the retention rates of a preheated thermoviscous composite resin (PHT) compared to a non-heated composite resin (NHT) in non-carious cervical lesions (NCCLs). A […]