Switzerland: A research team, including researchers from Nestle Research, revealed that a compound found in fenugreek and coffee, but also made in the gut microbiome, can improve muscle function in aging mice, humans, and worms. “Dietary trigonelline supplementation in male mice prevents fatigue and enhances strength during aging,” the researchers reported in Nature Metabolism. “We […]
A recent study published in the Joint Bone Spine journal unveiled comparative insights into the effectiveness of conventional synthetic disease-modifying anti-rheumatic drug (csDMARD) treatment strategies for rheumatoid arthritis (RA), focusing on patient retention rates between two popular treatment combinations. This study provides important data on the real-world application of triple therapy (methotrexate, sulfasalazine and hydroxychloroquine) […]
India: A recent prospective study published in Contact Dermatitis compared patch test positivity after 24 and 48 hours of occlusion time in patients with allergic contact dermatitis (ACD). The researchers reported no significant difference in patch test among ISS allergens after either occlusion time, 48 h occlusion performed significantly better versus 24 h when reactions of all allergens […]
China: A recent study showed a longer recurrence-free survival and overall survival with the combination of sorafenib and transarterial chemoembolization as postoperative adjuvant therapy among patients with hepatocellular carcinoma with portal vein tumor thrombus (PVTT). “The randomized clinical trial comprising 158 patients showed that both the median recurrence-free survival and median overall survival were significantly […]
Denmark: An arterial oxygen pressure (PaO2) target of 60 mm Hg versus 90 mm Hg led to more days alive without support in intensive care unit (ICU) patients with COVID-19 and severe hypoxemia, findings from HOT-COVID Randomized Clinical Trial have shown. The randomized trial, including 726 patients, found that targeting a Pao2 of 60 mm […]
A simple urine test can more than halve the number of cystoscopies necessary to follow up high-risk bladder cancer patients, new research has found. Cystoscopies involve inserting a flexible probe through the urethra into the bladder, which allows a clinician to look at the bladder lining for signs of cancer. While they are predominantly safe […]
Priovant Therapeutics recently unveiled promising results from the NEPTUNE Phase 2 study by testing the efficacy of brepocitinib in patients with non-anterior non-infectious uveitis (NIU) which can lead to severe visual impairment. This study highlights the potential of brepocitinib to revolutionize treatment paradigms in autoimmunity by specifically targeting a condition with few effective treatments currently […]
In the largest study to date on the subject, researchers found no evidence to support a causal link between acetaminophen use during pregnancy and increased risk of autism, ADHD and intellectual disability in children. The findings, using data from a nationwide cohort of over 2.4 million children born in Sweden, including siblings not exposed to […]
The US Food and Drug Administration has cleared Modius Stress to treat generalized anxiety disorder. Made by Neurovalens is a non-invasive electrical stimulation device for treatment of anxiety. Modius Stress becomes company’s second product cleared for use in US Neurovalens, a global leader in non-invasive neuro-technology, has received medical device clearance from the US Food […]
New research being presented at this year’s ESCMID Global Congress (formerly ECCMID) in Barcelona, Spain (27-30 April) suggests that the free-to-use, widely accessible ChatGPT could be an effective tool to help reduce vaccine hesitancy among the general public, as well as providing helpful advice on sexually transmitted infections (STIs) in conjunction with sexual health clinics, […]