China: A 24-week, phase 3 trial has shed light on the safety and efficacy of bexagliflozin versus dapagliflozin as an adjunct to metformin in Chinese patients with type 2 diabetes mellitus (T2D). Bexagliflozin and dapagliflozin are sodium-glucose cotransporter-2 (SGLT2) inhibitors. According to the study, bexagliflozin, when used in Chinese patients on metformin, showed nearly identical […]
A recent phase 2 clinical trial found positive outcomes in patients with pemphigus a rare and potentially life-threatening autoimmune disease. The study focused on the use of rilzabrutinib which is an oral, reversible, covalent Bruton tyrosine kinase (BTK) inhibitor to manage pemphigus. The results of this clinical trial were published in the recent issue of […]
Inflammatory bowel disease (IBD) is a chronic inflammatory condition of the gastrointestinal tract, affecting millions worldwide. Bowel resection is a common surgical intervention in IBD patients, with significant implications for quality of life. While vitamin D has been studied for its anti-inflammatory and immune-modulating properties, its association with bowel resection risk in IBD remains unclear. […]
Researchers at Tel Aviv University (TAU) and the Leviev Cardiothoracic and Vascular Center at the Sheba Medical Center have found a mechanism which is responsible for increasing the risk of developing cancer among patients with heart disease: those small extracellular bubbles, or vesicles (sEVs), that are secreted from the sick heart to heal itself are […]
A recent study that could revolutionize the treatment approach for severe gastroesophageal reflux disease (GERD) unveiled compelling evidence that support the efficacy of Potassium-competitive acid blockers (P-CAB) over the traditional Proton Pump Inhibitors (PPI) in treating grade C/D esophagitis. This severe manifestation of GERD requires active treatment and diligent follow-up due to its significant impact […]
South Korea: Findings from two Korean cohort studies revealed that simply lowering cholesterol intake may not be sufficient to prevent chronic kidney disease (CKD). The study was published online in Nutrition, Metabolism and Cardiovascular Diseases. The researchers showed that although cholesterol intake was associated with increased serum cholesterol levels, it was not associated with CKD […]
Esketamine is made from a drug called ketamine. It’s used as an anaesthetic and to treat depression, yet the effect for mothers with perinatal depression is unclear. Researchers have found in a new clinical trial that single low dose injection of esketamine given immediately after childbirth may reduce major depressive episodes in individuals with depressive […]
A recent study conducted at the First Affiliated Hospital of Chengdu Medical College uncovered a notable connection between the family history of gout and left ventricular (LV) diastolic dysfunction in patients with primary gout. The findings were published in the International Journal of General Medicine offer new insights into the hereditary factors influencing cardiac health […]
A new Society of Radiologists in Ultrasound (SRU) expert consensus statement to improve endometriosis evaluation was published today in the journal Radiology. Endometriosis is a common condition with substantial diagnostic delay, leading patients to experience pain, infertility, lost wages and interrupted relationships. The consensus provides recommendations for augmenting routine pelvic ultrasounds through additional maneuvers and […]
Pulmonary arterial hypertension is a rare and severe condition that impose significant challenges in pediatric populations in the individuals at increased risk due to genetic factors. A recent study by the team led by Yuan He unveiled the efficacy of treprostinil in treating the high risk pediatric patients with idiopathic or heritable pulmonary arterial hypertension […]