Entries by aaron

Anticoagulant Monotherapy alone, best for Stroke Prevention in AF with Atherosclerosis: JAMA

Researchers have found in a new study that in patients with nonvalvular atrial fibrillation (AF) and atherosclerosis, the addition of antiplatelet therapy to anticoagulants did not reduce ischemic events but significantly increased bleeding risk. Researchers conclude that anticoagulant monotherapy may be a safer option for this high-risk population. The study was published in JAMA Neurology […]

Inside Coldrif Scandal: Tamil Nadu Plant Used Paint-Grade Chemicals, Violated 300+ Drug Norms

Chennai: Officials from the Tamil Nadu Drugs Control Department uncovered horrific conditions at the Sresan Pharmaceuticals unit in Kancheepuram, where the now-banned Coldrif cough syrup was manufactured. The raid exposed open vats of boiling chemicals, leaking rusted pipes, and workers handling toxic substances without masks or gloves, a scene investigators described as a “factory of […]

EMDR Therapy Shows Effectiveness in Treating Personality Disorders: JAMA

Netherlands: A new study has shown that eye movement desensitization and reprocessing (EMDR) therapy led to significant reductions in personality disorder (PD) symptoms, with nearly half of the participants achieving diagnostic remission, highlighting its potential as an effective treatment option.               Personality disorders affect a substantial portion of the population […]

Routine H. pylori Screening Offers No Benefit of curbing bleeding risk After Acute MI: JAMA

According to a new study published in JAMA, in unselected patients with acute myocardial infarction, routine Helicobacter pylori screening did not significantly lower the risk of upper gastrointestinal (GI) bleeding. The study was published by Robin H. and colleagues. Upper GI bleeding is an established complication following myocardial infarction and frequently attributed to the anticoagulant […]

FDA Approves Oral Remibrutinib as First BTK Inhibitor for Chronic Spontaneous Urticaria

The FDA has approved oral remibrutinib as the first BTK inhibitor for chronic spontaneous urticaria in adults not responding to antihistamines. Rhapsido is a pill taken twice daily and does not require injections or lab monitoring. It is the first FDA-approved Bruton’s tyrosine kinase inhibitor (BTKi) for CSU. Rhapsido helps to inhibit the release of […]

Curcumin Lozenges Show Promise in Managing Oral Lichen Planus, reveals study

In a new study, curcumin lozenges demonstrated comparable pain relief to triamcinolone acetonide 0.1% paste after one and two weeks, while also reducing lesion size, pain, and burning sensation. The findings, published in Cureus by Harakh Chand Baranwal, Neelam Mittal, and colleagues, suggest that curcumin may serve as a safe and effective therapy for oral […]

Hanging Drop Sign in pelvis X-ray can be a useful tool to diagnose SNRA: study

Diagnosis of Seronegative Rheumatoid Arthritis (SNRA) is based on clinical, radiological, and MRI findings with set criteria. High specificity is provided by plain X-rays in the differential diagnosis of rheumatic disorders. In the study by C Rex et al of pelvis X-rays, they found that ischiopubic ramus enthesopathy was more common than sacroiliitis and they […]

Inhaled Heparin Cuts Risk of Ventilation and Death in COVID-19 Patients: Study

A meta-trial of randomized clinical studies across six countries has found that inhaled heparin significantly reduced the need for intubation, overall mortality, and in-hospital death among hospitalized COVID-19 patients. A widely available and affordable drug has been shown to be effective in treating seriously ill COVID-19 patients, according to a new international study led by […]

High Sucralose Intake May Lower Effectiveness of Immune Checkpoint Inhibitors in Cancer Patients: Study

Research published in Cancer Discovery suggests that high consumption of the artificial sweetener sucralose may reduce the effectiveness of immune checkpoint inhibitors (ICIs) in cancer patients. The research revealed that sucralose disrupted the balance of the gut microbiota, inhibited T cell function and metabolism, and eventually dampened the efficacy of immune checkpoint inhibitors (ICIs), i.e., […]