Pre-eclampsia (PE) is a major cause of maternal and perinatal morbidity and mortality. In the Combined Multimarker Screening and Randomised Patient Treatment with Aspirin for Evidence-based Preeclampsia Prevention (ASPRE) trial, treatment of high-risk women with aspirin 150mg daily from the first trimester to 36 weeks led to 62% and nearly 90% lower rates of PE […]
Around 5% of adults have depression world wide. The study found that higher mineral intake is linked to lower depression risk in Korean and American adults. Further research suggests that minerals like potassium and zinc may help reduce the risk of developing depression alongside healthy lifestyle habits. The study was published in the journal of […]
A new clinical trial published in the New England Journal of Medicine found that among patients with idiopathic normal-pressure hydrocephalus who responded to temporary cerebrospinal fluid (CSF) drainage, shunting significantly improved gait velocity and gait/balance measures at 3 months, but showed no benefit for cognition or incontinence. The study investigated the effects of shunting among patients […]
It has been found in real-world data from over 500 patients that a single dose of ARS Pharmaceuticals’ epinephrine nasal spray (neffy) achieved an 89% success rate, comparable to injection outcomes. This large-scale analysis supports neffy as a needle-free alternative for treating anaphylaxis. These findings represent the first large-scale analysis of treatment outcomes with neffy […]
In a preclinical study, researchers found tamoxifen encourages uterine cell growth; the findings could change how some breast cancers are treated in the future Studies show that people receiving tamoxifen, a highly effective and commonly used therapy to treat breast cancer, face a 2- to 7-fold increased risk of developing uterine cancer within 2-5 years […]
A new study published in Scientific Reports has established that sarcopenia enhances middle-aged and older Chinese adults’ risk of hip fractures. The study was conducted by Huang S. and colleagues. These results highlight the pressing need for early identification and intervention measures for sarcopenia to curb hip fracture risk and its long-term effects on the […]
Premenstrual symptoms can manifest at any point after menarche and considerably affect women’s quality of life, mental health and personal and work relationships, especially in severe cases. Premenstrual symptoms can be divided into somatic and psychological components. Somatic symptoms include abdominal pain, cramps, nausea, breast pain and swelling, whereas psychological symptoms are further divided into […]
Rib fractures are common injuries in critically ill patients and often result in severe pain, impaired ventilation, and a higher risk of pulmonary complications. Optimal analgesic strategies are essential to ensure effective pain control, minimize opioid use, and reduce secondary complications such as pneumonia or respiratory failure. While dexmedetomidine, a selective α2-adrenergic agonist, has shown […]
Researchers have found that patients with interstitial lung disease (ILD) are at greatly heightened risk of developing all major histological subtypes of lung cancer, including adenocarcinoma, squamous cell carcinoma, and small cell carcinoma. The study was published in JAMA Network Open by Hui Xu and colleagues. The research identified that ILD almost doubles the risk […]
The FDA has approved a subcutaneous (SC) induction regimen of guselkumab (Tremfya) for adults with moderately to severely active ulcerative colitis (UC). This makes guselkumab the first and only IL-23 inhibitor to provide both SC and intravenous (IV) induction options for treating UC and Crohn’s disease, offering patients flexibility including self-administration from the start of […]