A post hoc analysis of the SUMMIT trial, published in JACC, reveals that baseline body mass index (BMI) and fat distribution significantly affect the response to tirzepatide in patients with heart failure with preserved ejection fraction (HFpEF) and obesity. Patients who lost 15% or more of their body weight experienced greater improvements in exercise capacity, […]
An international team of researchers has made a key discovery: many children and young adults in Sub-Saharan Africa diagnosed with type 1 diabetes (T1D) may have a different form of the disease – one not caused by the immune system, unlike classic T1D. This discovery could change how diabetes is diagnosed, treated and managed across […]
According to a meta-analysis published in the European Journal of Preventive Cardiology, foods rich in flavan-3-ols-such as cocoa, tea, and certain fruits-may help lower blood pressure. Flavan-3-ols, found in cocoa, tea, and certain fruits, show promise in improving blood pressure (BP) and vascular function, but are currently not used for cardiovascular prevention. This meta-analysis evaluated […]
Frailty is a medically defined condition in older adults that increases vulnerability to everyday stresses, leading to a higher risk of falls, hospitalization and loss of independence. Warning signs of frailty include: Unintentional weight loss Moving slowly Feeling weak Persistent tiredness Low levels of physical activity Because most of these signs have a direct link […]
Pelvic floor dysfunction (PFD) presents significant issues related to pelvic organ abnormalities and dysfunction, particularly in the context of pregnancy and vaginal childbirth, which are recognized risk factors. Recent study aimed to enhance understanding of how pregnancy influences pelvic floor parameters and their association with stress urinary incontinence (SUI). Notably, SUI, characterized by involuntary urine […]
Women are less likely than men to receive drugs for multiple sclerosis (MS) between the ages of 18 to 40, during women’s childbearing years, even when those drugs have been shown to be safe for use during pregnancy or to have a prolonged effect against the disease even when stopped before conception, according to a […]
A new study published in the journal of BMC Pediatrics showed that compared to children without Kawasaki disease (KD), children with KD showed a slightly greater frequency of allergic diseases, particularly urticaria and rhinitis. Kawasaki disease is the primary source of serious heart problems, especially aneurysms in the coronary arteries. Although KD has distinct clinical […]
Children born by planned C-section have an increased risk of developing acute lymphoblastic leukaemia (ALL) later in life. This is shown by a study conducted by researchers at Karolinska Institutet. The researchers emphasise that the risk remains low. The study, published in The International Journal of Cancer, covers nearly 2.5 million children born in Sweden […]
Metronidazole effectively reduces pain in patients after a hemorrhoidectomy, suggests a new study published in BMC Surgery. Pain is a significant issue in post-hemorrhoidectomy. Metronidazole is being explored as an adjunctive pain management option. This meta-analysis of randomized controlled trials (RCTs) assesses metronidazole’s effectiveness and safety compared to a placebo post-hemorrhoidectomy, aiming to provide evidence-based […]
A diet high in foods with the potential to promote low grade inflammation during pregnancy may raise that child’s risk of developing type 1 diabetes, suggests Danish research published online in the Journal of Epidemiology & Community Health. This dietary pattern was associated with a 16% heightened risk for every unit increase in a dietary […]