Entries by aaron

TyG-BMI may predict Adverse Pregnancy Outcomes in IVF, suggests research

Researchers have found in a new study that higher triglyceride-glucose body mass index (TyG-BMI) was associated with increased miscarriage rates in both fresh and frozen embryo transfer (FET) cycles, along with reduced live birth rates in FET and cumulative live birth outcomes. TyG-BMI may serve as a practical marker to identify patients at higher metabolic […]

Women’s Childbirth Experiences in the WILL Randomised Trial: A Mixed Methods Analysis

Chronic or gestational hypertension complicates 7% of pregnancies, half of which will reach 37 weeks’ gestation. Observational data suggest that early term birth (at 37 to 38 weeks) may reduce maternal complications (e.g., preeclampsia), Caesareans, stillbirth and costs of maternal fetal surveillance; however, early term birth may increase neonatal morbidity. There are no high-quality data […]

Higher levels of air pollution linked to worsening of sleep apnea: ERS Stu

People who have obstructive sleep apnoea (OSA) may suffer worse symptoms if they live in areas with higher levels of air pollution, according to a multi-national study presented at the European Respiratory Society (ERS) Congress in Amsterdam, the Netherlands . Patients with OSA often snore loudly, their breathing starts and stops during the night, and […]

Mandibular Devices Effective for Severe Sleep Apnea with Hypertension: Study

Researchers have identified in a new study that mandibular advancement devices (MADs) are a valuable and acceptable treatment for patients with severe obstructive sleep apnea (OSA) and hypertension, offering significant improvements in sleep-related quality of life and blood pressure. Although continuous positive airway pressure (CPAP) is currently the gold standard treatment, this study demonstrates that […]

FDA Approves Palsonify for Acromegaly Treatment

The FDA has approved Palsonify™ (paltusotine) for adults with acromegaly who did not respond adequately to surgery or are not candidates for surgical treatment. PALSONIFY, a selectively-targeted somatostatin receptor type 2 nonpeptide (SST2) agonist, is now the first once-daily, oral treatment approved for adults with acromegaly. “With the FDA approval of our lead therapy Palsonify, […]

Stem cells may offer new hope for end-stage kidney disease treatment, suggests research

More than 4 million people worldwide have end-stage kidney disease that requires hemodialysis, a treatment in which a machine filters waste from the blood. Hemodialysis is a precursor to kidney transplant. To prepare for it, patients typically undergo surgery to connect an artery and a vein in the arm, creating an arteriovenous fistula (AVF) that […]

Mammograms May Benefit Women Well Into Their 80s, UCLA Study Finds

For many older women, the question of whether to continue breast cancer screening has been uncertain. While most guidelines recommend mammograms up to age 74, advice for women 75 and older has been less clear. Now, a new study from researchers at the UCLA Health Jonsson Comprehensive Cancer Center suggests that regular mammograms may still […]

Constipation May Increase Risk of Death in CKD and Heart Failure: Meta-Analysis Reveals

China: A new meta-analysis published in Annals of Medicine suggests that constipation may be associated with an increased risk of all-cause mortality, particularly among individuals with chronic health conditions such as chronic kidney disease (CKD) and heart failure. Interestingly, no clear link was observed between constipation and cardiovascular-specific mortality, highlighting the need for further research […]

High protein or Trp diet increases risk of cancer-associated VTE: Study

Next to cancer recurrence or progression, cardiovascular diseases are the leading causes of death in cancer survivors. The Surveillance, Epidemiology, and End Results database revealed that among the more than three million who initially survived cancer between 1973 and 2012, 38% eventually succumbed to the disease while 11.3% died from cardiovascular diseases. Specifically, cancer survivors […]