Australia: A case report published in BMC Nephrology by Seethalakshmi Viswanathan and colleagues from the Tissue Pathology & Diagnostic Oncology, Institute of Clinical Pathology and Medical Research, Westmead Hospital, Australia, has highlighted the severe renal consequences of untreated paroxysmal nocturnal haemoglobinuria (PNH) in a patient with a history of aplastic anaemia (AA). The report underlines […]
Researchers have determined that the red cell distribution width-to-albumin ratio (RAR), a composite biomarker of systemic inflammation and nutritional status, is linked to the risk of retinopathy in US adults over age 40. The new research identifies that the association between RAR and retinopathy is not linear and suggests that RAR may be a valuable […]
Significant risk factors associated with maternal and neonatal health stem from spontaneous preterm labor (PTL), which accounts for approximately 70% of preterm births. Current biomarkers lack prediction reliability, highlighting the need for novel, non-invasive indicators. Emerging research on tRNA-derived small RNAs (tsRNAs), however, shows promise in this exploration yet remains underinvestigated in relation to PTL. […]
A new study published in The Bone and Joint Journal showed that for the diagnosis of infections in the lower limbs associated with refractory fractures, positron emission tomography (PET)/CT is a useful diagnostic technique. A significant clinical problem is fracture-related infection (FRI), which frequently arises following fractures or surgical operations that specifically impact the lower […]
Recent study evaluated maternal serum neuroserpin concentrations in pregnancies affected by preeclampsia and their relationship with disease severity, considering neuroserpin’s roles in anti-inflammation and neuroprotection. This prospective case-control investigation was conducted from September 2024 to January 2025 at a tertiary referral hospital in Ankara, Türkiye, with a total of 88 participants: 44 diagnosed with preeclampsia […]
The FDA has approved Ajovy (fremanezumab-vfrm) for preventive treatment of episodic migraine in pediatric patients aged 6 to 17 years who weigh at least 45 kg. With this approval, AJOVY becomes the first and only calcitonin gene-related peptide (CGRP) antagonist indicated for the preventive treatment of episodic migraine in pediatric patients and migraine in adults, […]
In a major advance for patients with Crohn’s disease, a new study led by researchers at Mount Sinai Health System found that guselkumab, a medication with a mechanism of action that is new to inflammatory bowel disease (IBD) treatment, outperformed an established standard of care in promoting intestinal healing and symptom relief. These findings from […]
The MRI image shows a brain tumor in an inauspicious location, – and a brain biopsy will entail high risks for the patient, who had consulted us due to double vision. Situations such as this case discussion, cited by way of example, in a multidisciplinary team of cancer medicine experts prompted researchers at Charité – […]
China: A new community-based study from Jinan, China, has revealed that women with long-term exposure to secondhand smoke face a significantly higher risk of developing chronic obstructive pulmonary disease (COPD), alongside more severe symptoms and greater lung function decline. The research, led by Dr. Jiling Lv from the Department of Respiratory Medicine at Shandong Second […]
Researchers have discovered in a new study that patients in regions with higher sunlight exposure appear to have lower rates of postoperative hypoparathyroidism, suggesting sunlight may play a protective role in its prevention. Postoperative hypoparathyroidism is a common complication of thyroid surgery. Sunlight is a natural source of ultraviolet B (UVB) radiation, which facilitates the […]