A systematic review and meta-analysis of randomized controlled trials (RCTs) assessed whether weight loss interventions before in vitro fertilization (IVF) improved reproductive outcomes. The review found that weight loss interventions before IVF could increase the chances of pregnancy, especially in unassisted conception, although the effect on live births was unclear. The findings are published in […]
Recently published clinical trial aimed to evaluate the efficacy of hydromorphone as an adjunct to ropivacaine in serratus anterior plane block (SAPB) for postoperative analgesia and inflammatory response management in patients undergoing video-assisted thoracoscopic surgery (VATS). Methodology Patients aged 20-75 with American Society of Anesthesiologists classification I or II were randomized into three groups: Hydromorphone-Ropivacaine […]
Recent study evaluates the efficacy of mifepristone and misoprostol as a medical management option for missed miscarriage, aiming to identify significant risk factors affecting treatment success. Missed miscarriage, identified when a nonviable pregnancy is retained in the uterus, commonly leads to management via expectant, medical, or surgical means, with medical management increasingly favored for its […]
Ernakulam: Quashing the criminal proceedings against a doctor under Section 304 A of the Indian Penal Code, 1860, the Kerala High Court recently observed that a medical practitioner would only be liable under this section if he had committed a rash or negligent act that resulted in the patient’s death. “The law is thus well laid […]
The sudden, unexpected and medically unexplained death of an infant during sleep, Sudden Infant Death Syndrome (SIDS), remains to be fully understood. A European research group has now presented a new explanatory model in the current issue of the scientific journal Human Nature. This model focuses primarily on the exciting question of what role the […]
Patellofemoral arthroplasty (PFA) is an attractive option for patients who have isolated patellofemoral disease with the goal of reproducing normal joint function and kinematics while relieving pain, preserving the tibiofemoral joint, and providing longevity. Outcomes of many different implants and techniques, ranging from first-generation inlay design, to second-generation on lay design and now robotic or […]
A new study published in BMC Nephrology found that hydroxychloroquine (HCQ) therapy demonstrated a trend toward reducing proteinuria in patients with primary glomerular diseases. Importantly, HCQ did not significantly impact estimated glomerular filtration rate (eGFR), indicating preserved kidney function during treatment. The study also highlighted HCQ’s favorable safety profile, making it a promising adjunct therapy […]
Japan: Researchers have found in a new study that duodenal laparoscopy–endoscopy cooperative surgery is a promising procedure offering better outcomes and a lower complication rate compared to endoscopic resection (ER). However, its indications and feasibility should be evaluated on a case-by-case basis. The study, published in the Asian Journal of Endoscopic Surgery by Dr. Koji […]
Researchers found that the application of hyperbaric oxygen therapy (HBOT) in addition to current medical treatment significantly improves hearing gain in the case of sudden sensorineural hearing loss (SSNHL). SSNHL, an acute hearing impairment happening in thousands of individuals each year, is a challenging condition with unclear pathogenesis and variable responsiveness to treatment. The study […]
Phase 3 trials have demonstrated that tildrakizumab 100mg significantly improved ACR20 response rates in patients with active psoriatic arthritis at 24 weeks compared to placebo, marking a promising advancement in PsA treatment. Treatment with tildrakizumab 100 mg (ILUMYA) resulted in greater improvements in PsA signs and symptoms at Week 24 compared to treatment with placebo. […]