Entries by aaron

Double Relief: Study evaluates Synergistic Effects of Hydromorphone and Ropivacaine in Thoracoscopic Surgery

Recently published clinical trial aimed to evaluate the efficacy of hydromorphone as an adjunct to ropivacaine in serratus anterior plane block (SAPB) for postoperative analgesia and inflammatory response management in patients undergoing video-assisted thoracoscopic surgery (VATS). Methodology Patients aged 20-75 with American Society of Anesthesiologists classification I or II were randomized into three groups: Hydromorphone-Ropivacaine […]

A Gentle Approach: Study Evaluates Efficacy of Medical Management for Missed Miscarriage

Recent study evaluates the efficacy of mifepristone and misoprostol as a medical management option for missed miscarriage, aiming to identify significant risk factors affecting treatment success. Missed miscarriage, identified when a nonviable pregnancy is retained in the uterus, commonly leads to management via expectant, medical, or surgical means, with medical management increasingly favored for its […]

Resilience: What protects infants from sudden infant death syndrome?

The sudden, unexpected and medically unexplained death of an infant during sleep, Sudden Infant Death Syndrome (SIDS), remains to be fully understood. A European research group has now presented a new explanatory model in the current issue of the scientific journal Human Nature. This model focuses primarily on the exciting question of what role the […]

Favourable Outcomes are reported after Patellofemoral Arthroplasty with the Arthrex iBalance – A Third Generation Implant: study

Patellofemoral arthroplasty (PFA) is an attractive option for patients who have isolated patellofemoral disease with the goal of reproducing normal joint function and kinematics while relieving pain, preserving the tibiofemoral joint, and providing longevity. Outcomes of many different implants and techniques, ranging from first-generation inlay design, to second-generation on lay design and now robotic or […]

HCQ Shows Promise in Reducing Proteinuria in Primary Glomerular Diseases: Study

A new study published in BMC Nephrology found that hydroxychloroquine (HCQ) therapy demonstrated a trend toward reducing proteinuria in patients with primary glomerular diseases. Importantly, HCQ did not significantly impact estimated glomerular filtration rate (eGFR), indicating preserved kidney function during treatment. The study also highlighted HCQ’s favorable safety profile, making it a promising adjunct therapy […]

D-LECS Shows Promise Over endoscopic resection with Fewer Complications, Finds Study

Japan: Researchers have found in a new study that duodenal laparoscopy–endoscopy cooperative surgery is a promising procedure offering better outcomes and a lower complication rate compared to endoscopic resection (ER). However, its indications and feasibility should be evaluated on a case-by-case basis. The study, published in the Asian Journal of Endoscopic Surgery by Dr. Koji […]

Hyperbaric Oxygen Therapy Enhances Hearing Recovery in Sudden Sensorineural Hearing Loss Patients: Study

Researchers found that the application of hyperbaric oxygen therapy (HBOT) in addition to current medical treatment significantly improves hearing gain in the case of sudden sensorineural hearing loss (SSNHL). SSNHL, an acute hearing impairment happening in thousands of individuals each year, is a challenging condition with unclear pathogenesis and variable responsiveness to treatment. The study […]

Tildrakizumab Shows Significant Efficacy in Psoriatic Arthritis Phase 3 Trials

Phase 3 trials have demonstrated that tildrakizumab 100mg significantly improved ACR20 response rates in patients with active psoriatic arthritis at 24 weeks compared to placebo, marking a promising advancement in PsA treatment. Treatment with tildrakizumab 100 mg (ILUMYA) resulted in greater improvements in PsA signs and symptoms at Week 24 compared to treatment with placebo. […]

Mfn2 and Preeclampsia: Study Exploring a Potential Game Changer in Maternal Health: Study

Recent study investigates the expression of mitofusin 2 (Mfn2) in placentas and peripheral blood from patients with early-onset preeclampsia (eoPE) and late-onset preeclampsia (loPE), exploring its potential as a diagnostic and therapeutic target for preeclampsia. Preeclampsia, a serious condition occurring after 20 weeks of gestation, presents significant morbidity and mortality risks, particularly differentiating between eoPE […]