According to a recent study adding perioperative pembrolizumab to standard therapy such as surgery and radiotherapy with or without cisplatin consistently improves event-free survival (EFS) in patients with locally advanced head and neck squamous-cell carcinoma (HNSCC), researchers have discovered. Significantly, this increase in EFS was seen in patients with various levels of programmed death ligand […]
Researchers have found in a new cluster randomized trial that selecting men for osteoporosis screening by fracture risk factors and using a centralized screening model enhanced screening rates, treatment initiation, and medication adherence. The findings, published in JAMA, highlight a potential shift in how osteoporosis prevention and care can be effectively implemented in men, a […]
Topline results from the ATTAIN-2 trial have demonstrated that adults taking 36 mg orforglipron lost an average of 10.5% body weight at 72 weeks, with over half of participants on any dose achieving an HbA1c of 6.5% or lower. The oral GLP-1 demonstrated significant benefits for adults with obesity and type 2 diabetes. In the […]
The American College of Cardiology (ACC) has released new vaccination recommendations for adults with cardiovascular disease, advising immunization against COVID-19, influenza, RSV, pneumonia, and shingles. Published in JACC, the guidelines provide evidence-based support for each vaccine and include FAQs to guide discussions between patients and clinicians as part of routine prevention and treatment. The guidance […]
A new study published in the Journal of American Heart Association showed that degenerative valvular heart disease has been linked to an increased risk of rheumatoid arthritis (RA). Degenerative valvular heart disease (VHD) is a prevalent subtype of VHD that mostly affects people over 50 in high-income nations and is caused by age-related degenerative pathogeneses. […]
A new study led by investigators from Mass General Brigham, Harvard T.H. Chan School of Public Health, and the Broad Institute of MIT and Harvard suggests that a Mediterranean-style diet may help reduce dementia risk. The study, published in Nature Medicine, found that people at the highest genetic risk for Alzheimer’s disease benefited more from […]
Recent article compares two different pain management techniques used after upper abdominal surgeries. One is called intrathecal hydromorphone (ITH), where a pain medication is injected directly into the spinal fluid. The other is called a transversus abdominis plane (TAP) block, where numbing medicine is injected into the abdominal wall. The researchers found that patients who […]
A new study published in the Endocrine journal showed that nitazoxanide lowers inflammation and oxidative stress without compromising glucose regulation in type 2 diabetes. Hyperglycemia and anomalies in the metabolism of proteins, fats, and carbohydrates are hallmarks of diabetes mellitus (DM), a complicated metabolic disease. The majority of patients do not attain ideal glycemic control, even […]
For women diagnosed with early breast cancer, the long-term risk of developing a second primary cancer is low (around 2-3% greater than women in the general population), finds a study published by The BMJ today. The researchers say this information can help reassure many breast cancer survivors who believe their risk of a second primary […]
Researchers have found in new research that a single dose of dexamethasone may reduce surgical stress, as reflected by lower C-reactive protein (CRP) levels among patients undergoing laparoscopic abdominal surgery. The randomized controlled trial, published in BMC Surgery, investigated whether perioperative dexamethasone could attenuate the systemic inflammatory response triggered by minimally invasive abdominal procedures. Surgical […]