USA: A secondary analysis of the AZALEA-TIMI 71 randomized clinical trial, recently published in JAMA Cardiology, has highlighted the potential safety benefits of abelacimab, a novel factor XI inhibitor, compared with rivaroxaban in patients with atrial fibrillation (AF). The findings suggest that abelacimab may offer a more favorable bleeding profile across varying levels of kidney […]
Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization. The breakthrough in basic science has implications for human health – such as drug development and in vitro fertilization – and for bovine health and dairy industry sustainability. Scientists […]
Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function. Beta blockers have been the standard treatment for these patients for 40 years. This is a breakthrough discovery from the “REBOOT Trial” with senior investigator Valentin […]
India: A new prospective cohort study from India has revealed that consistent use of continuous positive airway pressure (CPAP) therapy not only alleviates obstructive sleep apnea (OSA) but also improves gastroesophageal reflux disease (GERD) symptoms. The research, led by Dr. Sohini Saha and Dr. Meghanad Meher from the Department of General Medicine, Institute of Medical […]
As endoscopic procedures become increasingly common, the choice of sedative agent used during these delicate procedures is of paramount importance. While propofol remains a widely utilized option, its limitations related to cardiovascular depression and injection pain have prompted the exploration of novel sedatives like remimazolam and ciprofol. A recent systematic review and network meta-analysis set […]
A new study published in the Journal of Clinical Oncology found women who breastfed after breast cancer did not face an increased risk of recurrence or contralateral disease. Many women were also able to breastfeed successfully after breast-conserving surgery, including from the affected breast. The POSITIVE trial evaluated the safety of temporarily interrupting endocrine therapy (ET) […]
USA: Use of common antidepressants may lower the risk of developing age-related macular degeneration (AMD) and slow its progression, according to a large U.S. database analysis. The findings suggest that selective serotonin reuptake inhibitors (SSRIs), serotonin-norepinephrine reuptake inhibitors (SNRIs), and tricyclic antidepressants (TCAs) could play a protective role against both non-exudative and exudative AMD, though […]
Chennai: Observing that the bond service posting orders should be issued within the bond period, the Madras High Court recently granted relief to a doctor by quashing her posting order, which was issued beyond the bond period. “It is well settled principle of law that the posting order should have been issued within the bond period, […]
Rishikesh: The All India Institute of Medical Sciences (AIIMS Rishikesh) has invited online applications for the post of Senior Resident (Non-Academic) on a tenure basis in different specialties in this medical institute. AIIMS, Rishikesh an Autonomous Institute of National Importance is one of the new AIIMS and apex healthcare being established by the Ministry of […]
New Delhi: The Supreme Court on Thursday heard a Public Interest Litigation (PIL) filed by the Federation of Medical and Sales Representatives Association of India, seeking statutory backing for the Uniform Code of Pharmaceutical Marketing Practices (UCPMP) to curb freebies offered by pharmaceutical companies to doctors. The matter came up before a bench of Justices […]