Entries by aaron

Exploring Buccal Prochlorperazine: A Targeted Review of Its Pharmacological Profile

The Clinical Value of Buccal Prochlorperazine Prochlorperazine remains a clinically valuable agent for managing nausea, dizziness, vertigo, and vestibular migraine. (1) However, oral administration is often limited by variable absorption, significant first-pass metabolism, and poor tolerability in symptomatic patients. With such clinical needs, buccal delivery serves as a relevant treatment option with potential advantages in […]

Chhattisgarh signs MoU for 240-bed super specialty hospital in Bastar

Raipur: The Chhattisgarh government on Wednesday signed a memorandum of understanding (MoU) with a Telangana-based hospital for operating a 240-bed super speciality hospital, built at a cost of Rs 200 crore in Jagdalpur, the headquarters of Bastar district in the state, an official said. Chhattisgarh’s Department of Medical Education and Continental Hospitals, Telangana, signed the MoU […]

Monoclonal Antibodies Drive Pathogenesis in Heparin-Induced Thrombocytopenia: NEJM

Heparin-induced thrombocytopenia (HIT) is a serious immune-mediated adverse effect of heparin therapy, characterised by thrombocytopenia and a high risk of thrombotic complications. Despite established clinical and laboratory diagnostic criteria, the precise immunopathogenesis of HIT remains incompletely understood. The identification of specific pathogenic antibodies could provide insights into disease mechanisms and guide the development of targeted […]

Early Metabolic Patterns in Prediabetes Help Predict Long-Term Complications: Study

A new long-term study published in the journal of Diabetes Care revealed that early metabolic patterns in prediabetes can forecast the risk of developing severe complications decades later in individuals at risk of type 2 diabetes (T2D). The findings highlight that while many people with prediabetes remain metabolically stable, specific subgroups face sharply increased risks of […]

FFR-Guided Complete Revascularization Beneficial in NSTEMI With Multivessel Disease: JAMA

Netherlands: Researchers have found in a new study that fractional flow reserve–guided complete revascularization during the index procedure is effective for patients with non–ST-segment elevation myocardial infarction (NSTEMI) and multivessel disease. The trial, published in JAMA and led by Dr. Tobias F.S. Pustjens from the Department of Cardiology at Zuyderland Medical Centre, the Netherlands, provides […]

Baricitinib not linked to increased VTE Risk in Alopecia Areata Patients: Study

A new study published in the International Journal of Dermatology revealed that alopecia areata patients treated with baricitinib had no reported thrombotic events over 6 months, indicating no increased risk of venous thromboembolism (VTE) in this population. Based on post-marketing data from patients with rheumatoid arthritis (RA) receiving tofacitinib, the European Medicines Agency (EMA) released […]

Extensive Gastric Atrophy Linked to Higher Risk of Esophageal Cancer: Study

Researchers have established in a new study that extensive gastric atrophy (GA) greatly increases the risk of esophageal squamous cell carcinoma (ESCC) development. This new large Japanese cohort study yields more compelling evidence, demonstrating that open-type GA independently elevates the risk of ESCC, even after risk factor adjustment for established risk factors including age, sex, […]

Worse outcomes with aspirin in high-risk chronic coronary syndrome patients who require long-term anticoagulation: ESC Study

Adding aspirin increased the risk of cardiovascular events, death and major bleeding in high-risk patients with chronic coronary syndrome (CCS) who had prior stenting and were receiving long-term chronic oral anticoagulation (OAC), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025 and simultaneously published in New England Journal of […]

Uterine Manipulators Enhance Laparoscopic Rectal Surgery Outcomes: Study

A recent study published in BMC Surgery found that uterine manipulators improve surgical exposure in laparoscopic rectal procedures in women without compromising oncological or perioperative outcomes. The research analyzed female patients undergoing laparoscopic rectal resection for benign and malignant conditions, comparing those in whom uterine manipulators were used with those operated on without them. Surgeons […]

’12k too low’: FMGs urge UP govt for stipend hike

New Delhi: The foreign medical graduates have urged the Uttar Pradesh Government to increase the stipend for medical graduates from abroad who are undergoing internship in the State. Currently, the FMGs undergoing internship get Rs 12,000 per month as their stipend. Pointing out that the stipend for FMG interns in Bihar was recently raised to Rs […]