Entries by aaron

Nonoperative Management of Pediatric Uncomplicated Acute Appendicitis Tied to Higher Failure and Complication Rates: JAMA

Brazil: A recent meta-analysis revealed increased treatment failure and major complications within a year among children and adolescents with uncomplicated acute appendicitis managed nonoperatively, emphasizing the need for individualized, patient-centered treatment decisions.                 The systematic review and meta-analysis published in JAMA Pediatrics by Isabella Faria and colleagues from the […]

Lavender-Neroli Aromatherapy Reduces Anxiety in Pediatric Dental Anesthesia: Study

Researchers have found in a new study that lavender–neroli aromatherapy was a safe, inexpensive, and effective complementary approach for lowering anxiety and discomfort in children undergoing dental anesthesia. The findings, published in Medical Sciences by Rama Abdalhai, Yasser Alsayed Tolibah, Racha Alkhatib, Chaza Kouchaji, and Ziad D. Baghdadi, highlight how simple, non-pharmacological interventions can improve […]

Carbonic anhydrase 3 protein in urine may be Potential Biomarker for ARAS: Study

A new study published in BMC Nephrology in 2025, reports that carbonic anhydrase 3 detected in urine may serve as a useful biomarker for monitoring renal injury in patients with atherosclerotic renal artery stenosis. The authors explain that this vascular condition reduces blood supply to the kidneys, leading to progressive functional decline, yet current diagnostic […]

Fludrocortisone 0.2 mg Study Rejected by CDSCO Panel Over Potential Adverse Effects

New Delhi: Noting the possible risk of expected adverse effects in healthy subjects, the Subject Expert Committee (SEC), functioning under the Central Drug Standard Control Organization (CDSCO), has declined to recommend a proposed clinical study by Advity Research Private Limited for Fludrocortisone Tablets USP 0.2 mg. This came after the firm presented the protocol along […]

Widely prescribed opioid painkiller tramadol not that effective for easing chronic pain

The strong opioid painkiller, tramadol, is not that effective at easing chronic pain for which it’s widely prescribed, finds a pooled data analysis of the available research, published online in BMJ Evidence Based Medicine. And it likely increases the risk of serious side effects, including heart disease, the findings indicate, prompting the researchers to conclude […]

3% Hypertonic Saline Nasal Irrigation Eases Allergic Rhinitis Symptoms but Not Superior to Isotonic Saline: Study

A new study published in the journal of Allergologia et immunopathologia showed that although there was no discernible improvement over isotonic saline, 3% hypertonic saline nasal irrigation decreased nasal symptoms and antihistamine usage in individuals with allergic rhinitis. There is ongoing discussion on the relative effectiveness of 0.9% isotonic saline and 3% hypertonic saline nasal […]

Infants with Sleep-Disordered Breathing and Severe Laryngomalacia Face Higher Surgery Risk: Study Suggests

USA: A new study published in the International Journal of Pediatric Otorhinolaryngology has highlighted clinical factors that can help predict the need for surgical intervention in infants with laryngomalacia. The findings offer valuable insights for clinicians aiming to optimize care and improve outcomes in affected infants. Laryngomalacia, the most common congenital laryngeal anomaly in infants, […]