Belgium: The European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) have released a 2025 Focused Update to their 2019 Guidelines for the management of dyslipidaemias, introducing crucial revisions and new recommendations based on recent scientific evidence. The update, published in the European Heart Journal, aims to refine approaches to cardiovascular (CV) risk […]
Canada: Women entering pregnancy with multiple chronic conditions (MCC) face significantly higher risks of severe maternal complications, including morbidity and mortality, according to a large population-based study from Ontario, Canada. The study also found that emergency department visits and hospitalizations were more frequent among these women, highlighting the need for tailored, multidisciplinary care. The […]
Compared with dual antiplatelet therapy (DAPT), a de-escalated DAPT strategy resulted in similar graft occlusion rates and reduced clinically relevant bleeding in patients who underwent coronary artery bypass grafting (CABG), according to late-breaking research presented in a Hot Line session today at ESC Congress 2025. Saphenous vein grafts remain the most frequently used conduits in […]
Taiwan: Children exposed to daily incense burning or those who had recently taken antibiotics face a significantly higher risk of developing acute bacterial paranasal sinusitis (ABPS), according to a recent study published in BMC Infectious Diseases. The research, led by Ting-Fang Chiu and colleagues from the Department of Pediatrics at Taipei City Hospital, highlights key […]
A new study published in the journal of BMC Surgery revealed that longer waiting times before hip fracture surgery were linked to higher 30-day mortality risk in elderly patients, with a threshold of around 42 hours marking significantly increased risk. This study from the Affiliated Kunshan Hospital of Jiangsu University conducted a retrospective cohort study […]
USA: A secondary analysis of the AZALEA-TIMI 71 randomized clinical trial, recently published in JAMA Cardiology, has highlighted the potential safety benefits of abelacimab, a novel factor XI inhibitor, compared with rivaroxaban in patients with atrial fibrillation (AF). The findings suggest that abelacimab may offer a more favorable bleeding profile across varying levels of kidney […]
Cornell researchers have uncovered the genetic triggers that cause male and female bovine embryos to develop differently, as early as seven to eight days after fertilization. The breakthrough in basic science has implications for human health – such as drug development and in vitro fertilization – and for bovine health and dairy industry sustainability. Scientists […]
Beta blockers-drugs commonly prescribed for a range of cardiac conditions, including heart attacks-provide no clinical benefit for patients who have had an uncomplicated myocardial infarction with preserved heart function. Beta blockers have been the standard treatment for these patients for 40 years. This is a breakthrough discovery from the “REBOOT Trial” with senior investigator Valentin […]
India: A new prospective cohort study from India has revealed that consistent use of continuous positive airway pressure (CPAP) therapy not only alleviates obstructive sleep apnea (OSA) but also improves gastroesophageal reflux disease (GERD) symptoms. The research, led by Dr. Sohini Saha and Dr. Meghanad Meher from the Department of General Medicine, Institute of Medical […]
As endoscopic procedures become increasingly common, the choice of sedative agent used during these delicate procedures is of paramount importance. While propofol remains a widely utilized option, its limitations related to cardiovascular depression and injection pain have prompted the exploration of novel sedatives like remimazolam and ciprofol. A recent systematic review and network meta-analysis set […]