Entries by aaron

Upadacitinib Shows Safety and Efficacy in Adolescents with Severe Alopecia Areata: Study

Alopecia areata (AA) is a chronic, immune-mediated disorder characterized by non-scarring hair loss, with profound psychological and social consequences, particularly among adolescents. While several therapeutic options exist, efficacy remains variable, and safe long-term treatments are limited for younger patients. Recently, Janus kinase (JAK) inhibitors have emerged as promising therapies, with upadacitinib—a selective JAK1 inhibitor—gaining attention […]

SOX2: a key player in prostate cancer progression and treatment resistance: Study

Prostate cancer remains a global health challenge, ranking as the second most common malignancy among men. While early-stage disease can be effectively managed, advanced forms-particularly metastatic castration-resistant prostate cancer (mCRPC)-pose significant therapeutic hurdles. A growing body of evidence highlights the pivotal role of SOX transcription factors, with SOX2 emerging as a central driver in tumor […]

Free exit option leaves TN MBBS seats largely unfilled

Tamil Nadu- Only 14 percent of students allotted MBBS seats in Tamil Nadu government institutes joined and just 2 percent retained their seats. This is reportedly because most candidates used the ‘free exit’ option to upgrade or choose later rounds. According to TOI report, an analysis of the seat matrix released by the Central Medical Counselling […]

Young-Onset Diabetes Tied to Beta Cell Deficiency, Not Obesity: PHENOEINDY-2 Study

India: A recent study published in Diabetologia has shed light on a unique presentation of type 2 diabetes among young adults in Assam, India-one that defies the conventional link between diabetes and obesity.  Conducted by Dr. Anupam Dutta and colleagues from the Department of Medicine, Assam Medical College and Hospital, Dibrugarh, the PHENOEINDY-2 study highlights […]

CDSCO Criminal Prosecution Against IndiaMART Put on Hold by Delhi HC Till Sept 17

New Delhi: The Delhi High Court has directed the Central Drugs Standard Control Organisation (CDSCO) not to enforce its order initiating criminal prosecution against IndiaMART Intermesh Limited over alleged listings of illegal drugs on its online platform. Justice Saurabh Banerjee, while posting the matter before the roster bench for hearing next week, ordered that CDSCO’s […]

Novo Nordisk Gets CDSCO Panel Nod for Rybelsus Label Update, Aligned with EMA

New Delhi: The Subject Expert Committee (SEC) under the Central Drugs Standard Control Organization (CDSCO) has recommended approval of an updated package insert for Rybelsus tablets (3 mg, 7 mg, and 14 mg), manufactured by Novo Nordisk (India) Private Limited. The decision came during the SEC meeting held on August 20, 2025, at CDSCO headquarters […]

Study Reveals Immunity Gaps in Vaccinated Children, Raising Concerns for Measles Elimination in India

USA: A new study published in JAMA Network Open by researchers from the Mayo Clinic Vaccine Research Group has found concerning immunity gaps among vaccinated children in southern India, raising questions about the effectiveness of measles vaccination strategies in achieving elimination goals. The cross-sectional study, led by Dr. Huy Quang Quach and colleagues, evaluated measles-specific […]

Steroidal MRAs Ineffective and Risky in Kidney Transplant Recipients: Study

Researchers have found in a new study steroidal mineralocorticoid receptor antagonists (MRAs) show no superior efficacy over placebo in kidney transplant recipients and are linked to a fourfold increased risk of hyperkalemia, even with preserved kidney function. In patients with chronic kidney disease, mineralocorticoid receptor antagonists (MRAs) exert a reno-protective effect through its anti-inflammatory and […]

Penile Implant Satisfaction Drops in Prostate Cancer Patients on Hormonal Treatment

Prostate cancer is the most common malignancy among men, with over 160,000 new cases diagnosed annually in the United States. Although advances in surgery, radiotherapy, and hormone therapy have extended survival, these treatments often result in complications that impact quality of life. Erectile dysfunction, reduced libido, and changes in intimacy remain common and distressing, affecting […]