Adults aged 80 and older experience the highest prevalence of cardiovascular disease, yet the optimal blood pressure targets for this group have been unclear in clinical guidelines. Now, a new study from Yale School of Medicine (YSM) suggests that intensive blood pressure management may offer important benefits for very elderly patients. As the American population […]
In a phase 3 trial Tegoprazan Shows Superior Efficacy and Safety in Treating Esophageal Conditions. It was found that Tegoprazan acted faster and was more effective than lansoprazole (a PPI), achieving all primary and secondary endpoints during the healing phase. It showed superior healing at weeks 2 and 8 across all EE grades. Further the […]
Researchers have determined in a new study that the elderly in Tamil Nadu have a three times greater incidence of tuberculosis (TB) than young adults. The State government of Tamil Nadu conducted a large-scale TB survey and screened more than 130,000 persons, identifying major risk factors for TB, including male gender, undernutrition, smoking, and previous […]
Data from a new clinical trial revealed that compared to sodium polystyrene sulfonate (SPS) treatment, Sodium zirconium cyclosilicate (SZC) provided faster and more effective resolution of hyperkalemia, with a potentially improved safety profile and better palatability in hemodialysis patients. The findings were published in the BMC Nephrology journal. Hyperkalemia is a frequent and potentially fatal […]
Recent study investigates the differences in anatomical dye distribution patterns and nerve blockade effectiveness between two catheter placement techniques for continuous adductor canal block (CACB) using a subsartorial approach. The comparison focuses on parallel and perpendicular orientations of catheter tips in relation to the saphenous nerve (SN) and the nerve to vastus medialis (NVM). An […]
Recently published randomized controlled trial involved 132 patients undergoing wide local excision of unilateral tongue cancer to evaluate the effectiveness of a lingual nerve block on managing haemodynamic surges and reducing opioid and volatile anaesthetic requirements. After recruitment, 14 patients were excluded due to protocol deviations, leaving a balanced comparison between two groups: one receiving […]
Egypt: A recent randomized clinical trial demonstrated that the intralesional measles, mumps, and rubella (MMR) vaccine is more effective than vitamin D3 in treating multiple warts, offering a promising alternative to traditional destructive therapies. In the study, published in the Indian Journal of Dermatology, Venereology and Leprology, 80.4% of patients in the MMR group (0.3 […]
Tocolytic medications are commonly used to delay preterm birth. Atosiban, an oxytocin receptor antagonist, is one such tocolytic used for threatened preterm labor. However, the effect of atosiban on improving neonatal outcomes remains unclear. This randomized controlled trial aimed to determine whether atosiban is superior to placebo in reducing morbidity in women with threatened preterm […]
Iran: A recent systematic review and meta-analysis has highlighted the alarming rise in myopia (short-sightedness) among children worldwide, attributing a significant part of this trend to the increasing use of digital devices. “Myopia affected 28.8% of children who used computers and video games, 35.4% of those who watched television, and 31.4% of smartphone users,” the […]
The FDA has granted accelerated approval to the combination therapy of avutometinib and defactinib (Avmapki Fakzynja Co-pack) for adults with KRAS-mutated, recurrent low-grade serous ovarian cancer who have previously undergone systemic therapy. This marks the first approved treatment specifically for this patient population, according to Verastem Oncology. This indication is approved under accelerated approval based […]