The U.S. FDA has approved Johnson & Johnson’s INLEXZO™ (gemcitabine intravesical system) for adults with BCG-unresponsive non-muscle invasive bladder cancer (NMIBC) with carcinoma in situ (CIS), with or without papillary tumors. This new therapy offers an alternative for patients who decline or are ineligible for bladder removal surgery (radical cystectomy). Gemcitabine intravesical system is co-packaged […]
A new study has investigated the impact of biologic therapies on cancer risk among patients with psoriasis and found that these treatments may offer protective benefits compared to traditional topical therapies. Psoriasis is a chronic immune-mediated condition that often requires long-term management, and concerns about the potential for systemic therapies to influence malignancy risk have […]
Netherlands: Wearing a valgus knee brace can meaningfully reduce walking-related pain in patients with medial compartment knee osteoarthritis (OA), according to a randomized controlled trial published in PLOS One. After six months of use, patients reported both statistically significant and clinically important improvements in pain intensity during walking, along with a reduced reliance on pain […]
USA: A prospective trial in gastrointestinal cancer patients found that preemptive DPYD/UGT1A1 genetic testing before chemotherapy was feasible, enabled timely results in over half of cases, and showed potential to lower treatment-related side effects and modifications. The research, led by Dr. Sony Tuteja from the Perelman School of Medicine at the University of Pennsylvania […]
A newly published retrospective cohort study (APeX‑P trial) in Journal of Allergy and Clinical Immunology: In Practice found that oral berotralstat—a once‑daily plasma kallikrein inhibitor—was well tolerated and highly effective in reducing hereditary angioedema (HAE) attack rates in children aged 2–11 years. Among the 29 pediatric participants (median age 8), berotralstat led to early and […]
A new study published in the journal of Pediatric Allergy and Immunology revealed that greater dietary diversity during pregnancy was associated with a reduced risk of atopic dermatitis in early childhood. The findings of the study emphasize on the potential protective role of maternal nutrition. The research followed 677 mother-infant pairs from pregnancy through the children’s […]
Kidney stone disease remains a growing health concern worldwide, with metabolic, inflammatory, and lifestyle factors all contributing to risk. New research now suggests that individuals with rheumatoid arthritis (RA) may be particularly vulnerable. In a large population-based study involving nearly 20,000 participants, researchers found that patients with RA experienced more than double the incidence of […]
A recent study published in the Journal of the American Medical Association found biparametric MRI to performs just as well as the current gold-standard multiparametric MRI in detecting clinically significant prostate cancer. The findings could reshape global diagnostic practices, particularly in health systems struggling with capacity and cost constraints. Multiparametric MRI has long been considered the […]
A recent study published in the journal of Eye revealed that low hemoglobin levels may significantly raise the risk of developing diabetic retinopathy (DR). The findings highlight hemoglobin as an overlooked but potentially modifiable risk factor in managing type 2 diabetes. The research used the TriNetX network from 2010 to 2022 and analysed data from […]
A simple fitness tracker might hold the key to revolutionizing maternal healthcare. Scientists at Scripps Research have found preliminary evidence suggesting that common wearable devices such as the Apple Watch, Garmin and Fitbit could remotely monitor pregnancy-related health changes by tracking physiological patterns-like heart rate-that correlate with hormonal fluctuations. “Wearable devices offer a unique opportunity […]