New Delhi: The drug major Johnson and Johnson has got approval from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) to conduct the phase III clinical study of the anti-cancer drug Talquetamab. This came after the firm presented Phase III Clinical Study Protocol No. 64407564MMY3009. Talquetamab is a bispecific […]
Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows. Overall, the rate of surgery-related opioid prescriptions dropped by 36% from 2016 to the end of 2022, and the average amount of opioids in those prescriptions dropped by 46%, […]
Thiruvananthapuram: In a significant development, the Kerala High Court on Friday, approved the bail application of a doctor who had faced suspension from the Indian Medical Association (IMA) following accusations of abetting the suicide of his girlfriend. Medical Dialogues team had earlier reported that the victim, a second-year postgraduate surgery trainee at Government Medical College, Thiruvananthapuram, […]
New Delhi: Rejecting the clinical trial waiver proposal, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has opined the drug major Zydus Healthcare to conduct a bioequivalence study (BE) of Glycopyrrolate plus Indacaterol Maleate Metered dose inhalation. This came after Zydus Healthcare presented a proposal along with BE protocol […]
Rahway: Merck, known as MSD outside of the United States and Canada, has announced the European Commission (EC) has approved two new indications for KEYTRUDA, Merck’s anti-PD-1 therapy, in gastrointestinal cancers: KEYTRUDA in combination with fluoropyrimidine- and platinum-containing chemotherapy, for the first-line treatment of locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative […]
Visakhapatnam: In a resounding display of excellence, the faculty and residents of the Department of Surgery of Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) garnered accolades at the 82nd Annual Conference of the Association of Surgeons of India (ASICON 2023), held in Visakhapatnam from 13th-16th December 2023. The prestigious ASICON event served as a […]
New Delhi: Pradhan Mantri Bhartiya Janaushadhi Pariyojana (PMBJP) has created another landmark in the history of generic medicines in the country by selling medicines worth Rs. 1000 Crore this year. This achievement was made possible only by the people of the country, who have saved approximately 5000 crores by purchasing medicines from Jan Aushadhi Kendras which […]
USA: Eplerenone was shown to significantly reduce arterial inflammation in a 12-month, placebo-controlled, randomized clinical trial of 26 well-treated persons with HIV (PWH) without known cardiovascular diseases (CVD). The researchers observed an even greater effect in the most diseased segment of the index vessel. “Mineralocorticoid receptor antagonism by Eplerenone may be a potential strategy to […]
Poland: A recent study published in the Journal of Cosmetic Dermatology has shown a significant impact of gluconolactone (GLA) chemical peel treatment on lowering skin pH and transepidermal water loss (TEWL). GLA was also observed to have seboregulatory properties. “GLA chemical peel treatment significantly lowered skin pH at all measurement points. Also, there was a […]
France: In a recent study published in Aging, the researchers performed a chemical screen, using an FDA-approved drug library, to identify compounds selectively promoting the death of CS-induced senescent lung cells. In the study, researchers Alberta Palazzo, and colleagues from France revealed that benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and […]