Entries by aaron

Colchicine fails to prevent atrial arrhythmia recurrence after ablation for AF, finds trial

Canada: Colchicine administration for ten days following catheter ablation reduced post-ablation chest pain and increased diarrhoea, however, it failed to reduce atrial arrhythmia recurrence or atrial fibrillation (AF)-associated clinical events, a small pilot trial showed. “Through 14-day Holter monitoring, colchicine failed to prevent the recurrence of atrial arrhythmia after ablation (31% versus 32% with placebo; […]

Cardiosphere-derived stem cells effective for treatment of pulmonary arterial hypertension

USA: Intravenous cardio-sphere-derived cells (CDCs) are safe in both the short and long term in subjects with pulmonary arterial hypertension (PAH), according to findings from Phase I clinical trial published in eBioMedicine, a Lancet journal. CDCs are heart-derived progenitor cells exhibiting immunomodulatory and anti-inflammatory effects, are anti-oxidative, anti-fibrotic, and anti-apoptotic to potentially impact several aspects […]

Smartphone-based technology helps in prevention of suicidal behavior

The use of smartphone technologies could be beneficial in preventing suicide among at-risk adults, says a study conducted by investigators from Italy and Spain, published online in the Journal of Psychiatric Research. Suicide stands among the primary causes of unnatural deaths globally. According to the WHO mortality database, suicides in the United States saw a […]

Ocular imaging may provide early information on microvascular damage in PAD patients

Peripheral artery disease (PAD) is a prevalent vascular disorder associated with atherosclerosis and reduced blood flow to the extremities. Affecting 8-10 million Americans and over 200 million people globally, it is a complex condition influenced by various risk factors like diabetes, smoking, hypertension, high cholesterol, and coronary artery disease. PAD leads to structural and functional […]

J&J Gets CDSCO Panel Nod to study anti-cancer drug Talquetamab

New Delhi: The drug major Johnson and Johnson has got approval from the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) to conduct the phase III clinical study of the anti-cancer drug Talquetamab. This came after the firm presented Phase III Clinical Study Protocol No. 64407564MMY3009. Talquetamab is a bispecific […]

Use of opioids in Surgery patients declining: JAMA

Post-surgery pain relief has shifted away from opioid-containing medications over the past seven years, but the downward trend has slowed since 2020, a new study shows. Overall, the rate of surgery-related opioid prescriptions dropped by 36% from 2016 to the end of 2022, and the average amount of opioids in those prescriptions dropped by 46%, […]

PG Medico Suicide Case: Kerala HC grants bail to doctor accused of dowry demands

Thiruvananthapuram: In a significant development, the Kerala High Court on Friday, approved the bail application of a doctor who had faced suspension from the Indian Medical Association (IMA) following accusations of abetting the suicide of his girlfriend. Medical Dialogues team had earlier reported that the victim, a second-year postgraduate surgery trainee at Government Medical College, Thiruvananthapuram, […]

Conduct bioequivalence study: CDSCO Panel tells Zydus Healthcare on Glycopyrrolate, Indacaterol Metered dose inhalation

New Delhi: Rejecting the clinical trial waiver proposal, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has opined the drug major Zydus Healthcare to conduct a bioequivalence study (BE) of Glycopyrrolate plus Indacaterol Maleate Metered dose inhalation. This came after Zydus Healthcare presented a proposal along with BE protocol […]

Merck gets European Commission nod for two new indications for Keytruda in gastrointestinal cancers

Rahway: Merck, known as MSD outside of the United States and Canada, has announced the European Commission (EC) has approved two new indications for KEYTRUDA, Merck’s anti-PD-1 therapy, in gastrointestinal cancers: KEYTRUDA in combination with fluoropyrimidine- and platinum-containing chemotherapy, for the first-line treatment of locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative […]

JIPMER General Surgery faculty, residents excel at ASICON 2023

Visakhapatnam: In a resounding display of excellence, the faculty and residents of the Department of Surgery of Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) garnered accolades at the 82nd Annual Conference of the Association of Surgeons of India (ASICON 2023), held in Visakhapatnam from 13th-16th December 2023. The prestigious ASICON event served as a […]