A comprehensive meta-analysis compared the treatment modalities for muscle-invasive bladder cancer (MIBC) by using either radical cystectomy (RC) or trimodal therapy (TMT). The findings were published in the Frontiers in Surgery. This meticulous study explored the academic databases such as Scopus, PubMed, Cochrane, EMBASE, and others from 1966 to December 2023. This yielded data from […]
Taiwan: A nationwide case-time-control study showed an increased miscarriage risk associated with benzodiazepine use during pregnancy after accounting for measurable confounders, and findings were unlikely to be due to unmeasured confounding. The findings published in JAMA Psychiatry indicate that healthcare professionals should meticulously balance the risk-benefit ratio when considering benzodiazepine use for treating sleep and […]
A novel PET imaging tracer has been proven to safely and effectively detect a common cancer gene mutation that is an important molecular marker for tumor-targeted therapy. By identifying this mutation early, physicians can tailor treatment plans for patients to achieve the best results. This research was published in the December issue of The Journal […]
Running Could Ease Irritable Bowel Symptoms suggests a new study published in the Neurogastroenterology & Motility. Physical activity has been suggested to alleviate gastrointestinal (GI) symptoms in patients with irritable bowel syndrome (IBS); however, evidence is scarce. Running has become increasingly popular and may be beneficial for patients with IBS. To obtain more insight in […]
Asthma is a heterogeneous disease characterized by chronic airway inflammation and respiratory symptoms such as cough, wheezing, shortness of breath, and chest tightness. It is a major source of childhood health burden worldwide and affects 10-12% of children. According to a study published in the Annals of Family Medicine, researchers have concluded that AI-aided home […]
China: A recent systematic review and meta-analysis showed a significant reduction in systolic blood pressure (SBP) with oral or subcutaneous semaglutide in patients with type 2 diabetes (T2D). Across 29 randomized controlled trials (RCTs), semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1 RA), was shown to notably reduce both body weight loss and glycated haemoglobin A1c […]
Recent research delving into the relationship between hypertension, cerebral small vessel disease, and brain health has uncovered intriguing differences based on gender. The study found sex-specific and age-dependent effects of hypertension on cerebral small vessel disease–related brain structural changes underscoring the importance of considering both sex and age at hypertension diagnosis when evaluating the impact […]
A new study published in the The Journal of Arthroplasty found that the size of hip implants used in total hip arthroplasty (THA) can have a substantial impact on patient outcomes. The research spanned over 16 years and included more than 10,000 primary THA cases, compared the clinical results of different head sizes, namely 28, […]
Recently published paper investigates the effectiveness of Mycobacteria indicus pranii (MIP) in enhancing clinical outcomes in sepsis patients. Sepsis is a major health concern, particularly in India. The authors conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) focusing on 28-day mortality as the primary outcome and several secondary outcomes like ICU stay […]
Digital impressions reduced clinical time for fabricating full-arch implant-supported prostheses suggests a new study published in the Journal of Prosthetic Dentistry. With the growing use of digital scanning, an evaluation of the clinical impact of digital scans versus conventional impressions in complete arch implant-supported prostheses is needed. However, systematic reviews on this subject are lacking. […]