Entries by aaron

Guselkumab tied with early improvement in psoriasis associated arthritis

Guselkumab associated with early improvement of joints and reduced progression of psoriatic arthritis suggests a new study published in the Clinical Rheumatology. Assess relationship between earlier clinical improvement and radiographic progression (RP) over 2 years in guselkumab-treated patients with active psoriatic arthritis (PsA). Post hoc analyses combined data from DISCOVER-2 biologic-naïve adults with active PsA […]

Bariatric surgery may improve left ventricular structure, function and strain

Bariatric surgery may improve left ventricular structure, function and strain suggests a new study published in the Journal of the American Heart Association. Obesity leads to an increased risk of cardiovascular disease morbidity and death, including heart failure. Bariatric surgery has been proven to be the most effective long‐term weight management treatment. This study investigated […]

Lung Cancer Risk High in Never-Smokers With Positive Family History: Lancet

The Taiwan Lung Cancer Screening in Never-Smoker Trial (TALENT) has revealed compelling insights into the prevalence and risk factors of lung cancer among non-smokers. The findings were published in the Lancet Respiratory Medicine. The study was conducted across 17 medical centers in Taiwan and primarily focused on individuals aged 55 to 75 years who never […]

Goniotomy Viable Option for Glaucoma Patients with Previous Surgical Failure

A recent study has shed light on the promising role of goniotomy (GT) as a potential solution for individuals facing glaucoma recurrence after prior unsuccessful surgeries. The study was published in The Journal Of Glaucoma by Lin and colleagues. This innovative approach, evaluated through a prospective multicenter study, offers hope for improved outcomes and better […]

Treatment with cyclobenzaprine sublingual tablets may reduce pain in fibromyalgia patients

Tonix Pharmaceuticals Holding Corp. (Nasdaq: TNXP) (Tonix or the Company), a biopharmaceutical company with marketed products and a pipeline of development candidates, today announced that the Phase 3 RESILIENT study evaluating TNX-102 SL (cyclobenzaprine HCl sublingual tablets) met its pre-specified primary endpoint in the second of two positive Phase 3 clinical trials, significantly reducing daily […]

Low carbohydrate intake from plant based foods and whole grains good for weight management: JAMA

USA: A recent study published in JAMA Network Open has revealed the importance of diet quality within low-carbohydrate diet (LCD) patterns for long-term weight management. The researchers stated, “Only LCDs that emphasized high-quality fat, protein and carbohydrates from whole grains and other plant-based foods were associated with less weight gain, while a lower-quality LCD was […]

High-risk PE patients have high mortality rates among patients with hemodynamic collapse

In a recent study from the Pulmonary Embolism Response Team (PERT) Consortium Registry found the contemporary care patterns and outcomes for high-risk pulmonary embolism (PE) patients. The findings of the study were published in the Journal of the American College of Cardiology. This research comprised a total of 5,790 patients by meticulously categorizing the individuals […]

Radical Cystectomy Improves Survival compared to Trimodal Therapy in Bladder Cancer

A comprehensive meta-analysis compared the treatment modalities for muscle-invasive bladder cancer (MIBC) by using either radical cystectomy (RC) or trimodal therapy (TMT). The findings were published in the Frontiers in Surgery. This meticulous study explored the academic databases such as Scopus, PubMed, Cochrane, EMBASE, and others from 1966 to December 2023. This yielded data from […]

Benzodiazepine use during pregnancy tied to a 69 per cent increased risk of miscarriage: JAMA

Taiwan: A nationwide case-time-control study showed an increased miscarriage risk associated with benzodiazepine use during pregnancy after accounting for measurable confounders, and findings were unlikely to be due to unmeasured confounding. The findings published in JAMA Psychiatry indicate that healthcare professionals should meticulously balance the risk-benefit ratio when considering benzodiazepine use for treating sleep and […]