Finland: A recent study published in JAMA Network Open has revealed type 1 diabetes (T1D) to be a risk factor associated with all subtypes of congenital heart defects (CHDs), while obesity and overweight were associated with certain CHD types, indicating distinct teratogenic mechanisms. The cohort study of over 620,000 children revealed that maternal T1D was […]
Totally magnetic technique effective option for sentinel lymph node detection and breast cancer localization suggests a new study published in the JAMA Surgery Guidewires have been the standard for breast lesion localization but pose operative and logistic challenges. Paramagnetic seeds have shown promising results, but to the authors’ knowledge, no randomized comparison has been performed. […]
In a recent clinical trial discovered promising outcomes of heat shock protein 90 inhibition by RGRN-305 for individuals suffering from moderate to severe Hidradenitis Suppurativa (HS), a painful immune-mediated disorder. This results were published in Journal of American Medical Association. The randomized clinical study was conducted from September 22, 2021, to August 29, 2022 at […]
Germany: A single-centre retrospective cohort study published in the Journal of the American College of Emergency Physicians Open has shed light on the association of preclinical blood glucose with hospitalization rate and in-hospital mortality. The researchers revealed that elevated prehospital blood glucose (PBG) ≥140 mg/dL was associated with a higher mortality risk, longer stay, and […]
Delhi: The National Medical Commission (NMC) has given a deadline to all students, who have proceeded abroad without obtaining an Eligibility Certificate, for submitting their deficiencies through the eligibility portal of NMC. 1060 applicants are mentioned in the list released the NMC. The NMC notified on the recent scrutiny process of applications received for eligibility […]
New Delhi: Reviewing the drug major AstraZeneca’s Phase III clinical trial protocol of the anti-cancer drug of Dato-DXd and Durvualumab, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has recommended the firm to submit supportive documents for the selection of Durvalumab dose of 1120mg every three weeks instead of […]
The use of a single dose of intra-articular antibiotic (IAA) has been reported in reducing the rate of prosthetic joint injection after total hip and knee arthroplasty. A.W.R. Burns et al examined the safety of IAA in primary hip and knee replacement surgery and the blood levels and joint fluid levels of vancomycin utilising this […]
A recent retrospective study by John Locke and team suggests important inputs on the efficacy and safety of various methods for jejunostomy tube placements which provides enteral access for patients who are unable to meet nutritional needs orally. The findings were published in the journal of Gastrointestinal Endoscopy. The study was conducted to compare procedural […]
Germany: A recent study showed a low risk of implantable cardioverter-defibrillator (ICD) damage or overheating during transcranial magnetic stimulation (TMS), used for treating several neuropsychiatric disorders, even when stimulation was much stronger than normal. The findings were published online in JACC: Clinical Electrophysiology on January 3, 2024. Multiple experiments indicated that electromagnetic therapy for depression […]
Agitation in dementia is commonly reported and has a negative effect on patient functioning, health outcomes, and quality of life increases caregiver distress and time spent caring and may contribute to the patient being institutionalized. Brexpiprazole is a rarely prescribed antipsychotic that acts on noradrenergic, serotonergic, and dopaminergic neurotransmitter systems, which are implicated in the […]