Entries by aaron

Totally magnetic technique effective option for sentinel lymph node detection and breast cancer localization

Totally magnetic technique effective option for sentinel lymph node detection and breast cancer localization suggests a new study published in the JAMA Surgery Guidewires have been the standard for breast lesion localization but pose operative and logistic challenges. Paramagnetic seeds have shown promising results, but to the authors’ knowledge, no randomized comparison has been performed. […]

Heat shock protein 90 inhibition effective and safe option against Hidradenitis Suppurativa

In a recent clinical trial discovered promising outcomes of heat shock protein 90 inhibition by RGRN-305 for individuals suffering from moderate to severe Hidradenitis Suppurativa (HS), a painful immune-mediated disorder. This results were published in Journal of American Medical Association. The randomized clinical study was conducted from September 22, 2021, to August 29, 2022 at […]

Elevated preclinical blood glucose may increase hospitalization and associated mortality risk of patients

Germany: A single-centre retrospective cohort study published in the Journal of the American College of Emergency Physicians Open has shed light on the association of preclinical blood glucose with hospitalization rate and in-hospital mortality. The researchers revealed that elevated prehospital blood glucose (PBG) ≥140 mg/dL was associated with a higher mortality risk, longer stay, and […]

Justify Durvalumab dose: CDSCO Panel Tells AstraZeneca on Study of Dato-DXd and Durvalumab

New Delhi: Reviewing the drug major AstraZeneca’s Phase III clinical trial protocol of the anti-cancer drug of Dato-DXd and Durvualumab, the Subject Expert Committee (SEC) functional under the Central Drug Standard Control Organisation (CDSCO) has recommended the firm to submit supportive documents for the selection of Durvalumab dose of 1120mg every three weeks instead of […]

Use of intra-articular vancomycin safe in primary hip and knee arthroplasty

The use of a single dose of intra-articular antibiotic (IAA) has been reported in reducing the rate of prosthetic joint injection after total hip and knee arthroplasty. A.W.R. Burns et al examined the safety of IAA in primary hip and knee replacement surgery and the blood levels and joint fluid levels of vancomycin utilising this […]

Can transcranial magnetic stimulation damage or interact with implanted cardiac devices?

Germany: A recent study showed a low risk of implantable cardioverter-defibrillator (ICD) damage or overheating during transcranial magnetic stimulation (TMS), used for treating several neuropsychiatric disorders, even when stimulation was much stronger than normal. The findings were published online in JACC: Clinical Electrophysiology on January 3, 2024. Multiple experiments indicated that electromagnetic therapy for depression […]

Less dosage of Brexpiprazole efficient to treat agitation in dementia

Agitation in dementia is commonly reported and has a negative effect on patient functioning, health outcomes, and quality of life increases caregiver distress and time spent caring and may contribute to the patient being institutionalized. Brexpiprazole is a rarely prescribed antipsychotic that acts on noradrenergic, serotonergic, and dopaminergic neurotransmitter systems, which are implicated in the […]

GERD has no causal impact on susceptibility and prognosis of idiopathic pulmonary fibrosis

China: The link between gastroesophageal reflux disease (GERD) and its potential impact on susceptibility to idiopathic pulmonary fibrosis (IPF) may not be of a direct causal nature; it could be impacted by factors such as smoking, a recent Mendelian randomization (MR) study has revealed. The findings published in BMC Pulmonary Medicine did not reveal any […]