Entries by aaron

ADA releases new guideline for pharmacologic management of acute dental pain in adults, adolescents and older adults

USA: A recent article published in The Journal of the American Dental Association has reported key recommendations and good practice statements for the pharmacologic management of acute dental pain: postoperative pain after simple and surgical tooth extraction(s) in adolescents, adults, and older adults. The document stated, that there is a beneficial net balance favoring the […]

Cefepime-taniborbactam superior to meropenem in treating complicated UTIs and acute pyelonephritis: NEJM

Carbapenem-resistant Enterobacterales species and multidrug-resistant Pseudomonas aeruginosa pose significant global health threats. Cefepime–taniborbactam is an investigational β-lactam and β-lactamase inhibitor combination with activity against these organisms. A study published in The New England Journal of Medicine (NEJM) concluded that Cefepime-taniborbactam was more effective than meropenem in treating complicated urinary tract infections involving acute pyelonephritis and […]

Taxane-based chemotherapy in Asian breast cancer patients tied to skin changes, hair loss: Study

South Korea: A recent study published in The Journal of Dermatology evaluated the effects of treatment regimens in Asian breast cancer (BC) patients. The researchers revealed significantly increased odds of experiencing elevated hair loss, a higher melanin index & increased wrinkles six months post-surgery in those in the adjuvant treatment group, particularly those undergoing taxane-based […]

Cardio-oncology patients may have a high prevalence of sleep apnea and risk of CHF

Cardio-Oncology Patients may have high prevalence of sleep apnea and risk of CHF suggests a new study published in the American College of Cardiology. Sleep apnea is prevalent among patients at higher risk for developing congestive heart failure (CHF) following cancer treatment and could be used as a risk factor to identify patients who would […]

Increased age-related macular degeneration risk in patients with CKD: Study

A recent study conducted by the Asian Eye Epidemiology Consortium discovered a significant association between Chronic Kidney Disease (CKD) and susceptibility to Age-Related Macular Degeneration (AMD) in Asian populations. The findings published in the Ophthalmology journal highlighted the shared risk factors, pathogenic mechanisms and genetic polymorphisms that may elevate the risk of AMD in individuals […]

Bacteriophage therapy helps treat drug-resistant E. faecium infection: Case study

 It was a last-ditch effort. For years doctors had tried to keep a patient’s recurrent drug-resistant bacterial blood infection at bay, but it kept coming back and antibiotics were no longer working. The family agreed to try an experimental treatment that uses viruses to kill bacteria. The patient’s Enterococcus faecium bacterial strain, which had become […]

AVP-786 disappoints in treatment of agitation-associated dementia due to Alzheimer’s in initial findings

Agitation associated with dementia caused by Alzheimer’s disease is a prevalent neuropsychiatric symptom affecting approximately half of all Alzheimer’s dementia patients. This condition substantially impacts the quality of life for patients, their families, and caregivers. Agitation associated with dementia caused by Alzheimer’s disease encompasses various behaviors such as pacing, gesturing, profanity, shouting, shoving, and hitting. […]

Migraine and vasomotor symptoms may increase CAD risk among young adults: Study

Migraine and vasomotor symptoms may increase CAD risk among young adults suggests a new study published in the Menopause. A study was done to examine whether vasomotor symptoms (VMS) and migraine headaches, hypothesized to be vasoactive conditions, are associated with a greater risk for cardiovascular disease (CVD) events including strokes. They performed secondary data analysis […]

Comparative Safety of Midline Catheters and PICCs in Long-term Intravenous Therapy

In a recent groundbreaking trial conducted at a Danish academic tertiary care center, researchers have shed light on the safety and efficacy of midline catheters (MCs) compared to peripherally inserted central catheters (PICCs) in adult patients requiring intravenous therapy for a duration of 5 to 28 days. The trial found that there was a low […]