There seems to be a J-shaped curve between dietary thiamine (vitamin B1) and worsening mental acuity among cognitively healthy older people, suggests research published in the open access journal General Psychiatry. The sweet spot seems to be a daily intake of 0.68 mg, below which there is relatively little impact. But higher daily intake was […]
Sepsis is a life-threatening condition triggered by a severe infection. Severe sepsis and septic shock are progressive stages of sepsis, associated with multi-organ failure and death. Mortality for pediatric sepsis ranges from 4% to 50%, depending on illness severity, risk factors, and geographic location. The risk of recurrence after surviving severe sepsis is significantly high […]
USA: A recent study published in Science Signaling has revealed that a pannexin channel protein may be protective against obesity-related hypertension. Endothelial pannexin 3 (Panx3) and Bcl6 abundance were reduced in hypertensive, obese individuals, indicating that reductions in endothelial Panx3 may drive obesity-associated hypertension. “Our findings provide insight into a channel-independent role of Panx3 wherein […]
Anorexia nervosa affects males as well as females, and affected males have a sixfold higher mortality rate than males in the general population. A new article published in CMAJ (Canadian Medical Association Journal) aims to raise awareness of this life-threatening eating disorder. “Early identification and prompt treatment are essential,” writes Dr. Basil Kadoura, a specialist […]
A recent study published in the BMJ Thorax unveiled the intricate relationship between female reproductive factors and the development of Chronic Obstructive Pulmonary Disease (COPD). This research looks into how aspects like the age at menarche, childbirth, miscarriage, stillbirth and menopause could influence the susceptibility of woman to COPD. This study analyzed data across three […]
Iran: A recent systematic review published in PLOS One has revealed the positive impact of implementing social media interventions on multiple aspects of oral health among laypeople. Online platforms such as Instagram, WhatsApp, YouTube, and Telegram can be effectively utilized to promote oral health among patients, the researchers suggested. They note that although social media […]
Canada: A recent study published in Cardiovascular Research has shed light on restoring blood vessel regeneration in the era of the combination of SGLT2 inhibitors and GLP-1 receptor agonist therapy for diabetes and obesity. In the study, David A Hess, University of Western Ontario, London, Canada, and colleagues focused on the clinical potential of SGLT2i […]
A recent study found the association between weight change and the development of hand osteoarthritis (OA) was investigated. The study published in the Arthritis Care & Research assessed if weight loss or gain have any bearing on the incidence and progression of hand OA along with the development and resolution of hand pain. The study […]
USA: Treatment with dapagliflozin in patients with chronic kidney disease (CKD) and albuminuria is associated with modest but clinically meaningful reductions in systolic blood pressure (SBP), according to a pre-specified analysis of data from the DAPA-CKD trial. In the study published in the American Heart Journal, the placebo-adjusted reduction in systolic BP was evident soon […]
Recently published study reviewed the impact of multimorbidity on the recovery trajectories and outcomes of critical illness survivors, aiming to identify factors that predispose such survivors to worse outcomes and explore potential strategies to enhance their long-term recovery. Influence of Multimorbidity on Critical Illness Outcomes The study notes that previous research efforts have largely focused […]