A recent study published in the Nature Scientific Reports uncovered the role of antiplatelet therapy (AP) in reducing the severity of the COVID-19 and improving patient outcomes. The study involved a total of 2170 hospitalized COVID-19 patients with a mean age of 60 years and delved into the interplay between hyperinflammation, disruptions in coagulation processes […]
China: A recent study published in The Journal of Dermatology has suggested ofatumumab to be a promising treatment option for patients with refractory pemphigus vulgaris. The researchers showed that ofatumumab subcutaneous injection successfully treated patients with pemphigus vulgaris (PV) relapse post rituximab. Wei Li, Sichuan University, Chengdu, China, and colleagues reported outcomes in three pemphigus […]
The phase 3 DISCOVER-2 clinical trial published in the Rheumatology and Therapy journal revealed significant advancements in the treatment of psoriatic arthritis (PsA). The study evaluated the impact of guselkumab on work productivity and general health and showed encouraging outcomes over a span of two years. Among the biologic-naïve patients with active PsA, this trial […]
USA: The US Food and Drug Administration (FDA) has approved a paclitaxel-coated device, AGENT, for treating in-stent restenosis, making it the first coronary Drug-Coated Balloon (DCB) to receive approval in the US, Boston Scientific announced. AGENT Drug-Coated Balloon is indicated to treat coronary in-stent restenosis (ISR) in patients with coronary artery disease (CAD). ISR is […]
Intrommune Therapeutics has been revolutionizing food allergy treatment and it has recently unveiled significant data that supports Oral Mucosal Immunotherapy (OMIT) as a promising new avenue for treating food allergies, particularly peanut allergies. OMIT is an investigational treatment that delivers allergenic proteins via a specially formulated toothpaste by offering a convenient alternative to existing therapies. […]
India: The Lipid Association of India (LAI) has released updated heart disease guidelines for Indian patients. The guideline was published online in the Journal of Clinical Lipidology on February 8, 2024. In 2016, the LAI developed a cardiovascular risk assessment algorithm and defined low-density lipoprotein cholesterol (LDL-C) goals for preventing atherosclerotic cardiovascular disease (ASCVD) in […]
A recent study published in the Journal of Stroke and Cerebrovascular Diseases found that a moderate-intensity statin combined with ezetimibe could be a potential therapy for high-risk stroke patients. This discovery challenges conventional wisdom regarding high-intensity statin therapy, suggesting a more effective and safer alternative. This randomized controlled trial involved participants with acute ischemic cerebrovascular […]
China: A randomized controlled trials (RCTs) meta-analysis published in the Medicine Journal has shed light on the safety and efficacy of dorzagliatin, a novel glucokinase activator, in treating type 2 diabetes mellitus (T2DM). The researchers revealed favourable effects of dorzagliatin in hypoglycemic control and effectively reduced the glycated haemoglobin (HbA1c), fasting blood glucose (FBG), and […]
A recent comparative effectiveness study published in the Journal of American Medical Association highlights the long-term benefits of colonoscopy versus sigmoidoscopy in reducing colorectal cancer (CRC) incidence and mortality. The study was conducted by pooling data from four randomized sigmoidoscopy screening trials in Norway, Italy, the US and UK that offers valuable insights into the […]
A recent study by Dominika Ambrożej explored the effectiveness of intravenous magnesium sulfate (IV-MgSO4) as a secondary treatment for acute asthma exacerbations in children. Asthma is the most prevalent chronic disease affecting children worldwide that poses a significant healthcare burden by prompting the urgent need for reliable secondary therapies. The key findings were published in […]