Entries by aaron

Once-weekly administration of apraglutide reduces dependency on parenteral support in short bowel syndrome: Phase 3 trial

USA: Findings from phase 3 STARS trial demonstrate the potential for apraglutide to improve the standard of care for all adult patients with short bowel syndrome with intestinal failure (SBS-IF) dependent on parenteral support as the only GLP-2 with once-weekly administration, if approved.  The study showed that treatment with apraglutide was associated with a reduction […]

FDA approves semaglutide for major heart disease prevention among obese

The US Food and Drug Administration (FDA) has approved semaglutide (Wegovy) for reducing risk of cardiovascular death, heart attack, and stroke in adults with cardiovascular disease and either obesity or overweight. Wegovy should be used in addition to a reduced calorie diet and increased physical activity. Cardiovascular disease is a group of diseases of the […]

Higher intake of nuts in early pregnancy enhances neuropsychological development and reduces peer problems in children: Study

It is already known that Maternal diet during pregnancy is associated with child development. Nuts are nutrient-dense foods and provide fatty acids, vitamins, fibre, minerals and proteins. Pregnant women who consume nuts may potentially reduce the likelihood of their 5-year-old children experiencing peer problems, according to a study published in the Journal of Pediatric Gastroenterology […]

Full-mouth rehabilitation with dental implants viable option for patients with cognitive and physical disabilities: Study

UK: A 14-year cohort study published in the Journal of Prosthetic Dentistry has found implant-supported prostheses to be effective and that oral rehabilitation under the specified conditions is stable. The researchers suggest that clinicians should consider this full-mouth rehabilitation with dental implants under general anesthesia (GA) as a viable option for cognitively and physically disabled […]

Mazdutide Shows Promise in Controlling blood sugar and Obesity in Diabetes Patients: Study

Mazdutide, a dual agonist drug was found to target weight reduction and additionally to manage blood glucose levels in individuals with overweight and obesity. The key highlights of this study was published in the recent edition of Frontiers in Endocrinology. Amidst the anticipation surrounding the efficacy of Mazdutide, the concerns regarding the scarcity of comprehensive evidence […]

KDIGO 2024 Guideline for ANCA Vasculitis management aims to improve care

USA: An article published in Kidney International reports a new guideline from Kidney Disease: Improving Global Outcomes (KDIGO) that provides updated recommendations on the management of antineutrophilic cytoplasmic antibody (ANCA)–-associated vasculitis (AAV). The updated guideline addresses key recent developments, the recent regulatory approval of the C5a receptor inhibitor avacopan as an add-on therapy to the […]

Rapid syndromic PCR tests tied to more targeted antibiotic treatment for pneumonia: JAMA

Researchers have found in a new randomized trial that rapid syndromic PCR tests could complement or replace culture-based diagnostic methods for pneumonia. Lower respiratory tract infections, including CAP (community-acquired pneumonia), cause hospital admissions and mortality. Molecular tests can potentially optimize treatment decisions and CAP management, but limited evidence exists to support their routine use. According […]

Unsuccessful Angioplasty: Cardiologist, Hospital slapped Rs 2 lakh compensation

Hoshiarpur: The District Consumer Disputes Redressal Commission, Hoshiarpur, recently slapped Rs 2 lakh compensation on a private hospital and its Cardiologist for an unsuccessful Coronary Percutaneous Old Balloon Angioplasty procedure on a patient. Observing that the doctor had not been vigilant while performing the procedure, the Commission noted, “…we conclude/ deduce that the OP 1 and […]

USFDA delays decision on Eli Lilly Alzheimer’s drug Donanemab

United States: The U.S. Food and Drug Administration has delayed its decision on Eli Lilly’s experimental treatment for early Alzheimer’s disease and will hold a meeting of outside experts to discuss its safety and efficacy, the company said. The FDA’s decision came as a surprise to company officials and many Alzheimer’s experts, who had expected […]