USA: A post hoc secondary analysis of a randomized clinical trial (TODAY) of 398 participants with youth-onset type 2 diabetes (T2D) revealed that growth hormone mediators may be linked with the unique phenotype of pediatric T2D. The study, published in JAMA Network Open, suggests that changes in plasma growth hormone mediators are linked with loss […]
New eye drop treatment has been found to be safe and tolerable with 100% participants completing the study for diabetic retinopathy and diabetic macular edema, according to data recently released for the phase 1b/2a trial. These data demonstrate the safety and tolerability of EXN407, as well as clear indications of biological activity, positioning it well […]
Psoriatic arthritis is a chronic inflammatory condition that affects joints and skin, often causing pain, swelling, and skin lesions. Biologic therapies like guselkumab and ustekinumab have shown promise in managing PsA, but direct comparisons of their efficacy remain scarce. A recent study published in Rheumatology and Therapy provides compelling evidence regarding the efficacy of guselkumab […]
People with depression face an increased risk of cardiovascular disease (CVD); however, more women experience CVD following a depression diagnosis than men, according to a new study published today in JACC: Asia. The study investigates the connection between depression and CVD, shedding light on potential mechanisms that contribute to its sex-based differences and underscoring the […]
Research in animals has shown that the diabetes drug dulaglutide, which is a glucagon-like peptide-1 (GLP-1) receptor agonist may reduce symptoms of depression. A new study published in Brain and Behavior reveals the mechanisms that are likely involved. By conducting a range of tests in mice treated with and without dulaglutide, investigators confirmed the effects […]
Patients undergoing imaging procedures often experience psychological distress and discomfort. In response to this challenge, researchers have explored the effectiveness of musical intervention (MI) in alleviating patient anxiety and improving overall comfort during medical imaging. A recent systematic review (SR) and meta-analysis (MA) sought to evaluate the impact of MI on psychophysiological outcomes in this […]
Obesity, which could reach 50% of the population in certain developed countries by 2030, is a major public health concern. It not only affects the health of those who suffer from it, but could also have serious consequences for their offspring. Scientists at the University of Geneva (UNIGE) and the Geneva University Hospitals (HUG) have […]
Women with a short cervix around 20 weeks of pregnancy have an increased risk of preterm birth. Preventing preterm birth in pregnant women with a short cervix is a crucial step in protecting the health of the child. Research from Amsterdam UMC now shows that, in pregnant women with a short cervix around 20 weeks, […]
The association between statin use and Alzheimer’s disease (AD) risk, especially in relation to the APOE ε4 allele, has been unclear. A recent longitudinal cohort study aimed to investigate whether statin initiation affects incident AD and cognitive decline differently depending on APOE ε4 status. This study was published in the Neurology journal by Kumar Rajan […]
A collaborative study between a bariatric and transplant surgery team has introduced new hope for patients suffering from end-stage renal disease (ESRD) who are also struggling with obesity. The study authors explored the outcomes of metabolic and bariatric surgery in ESRD patients and whether the surgery can improve their eligibility for kidney transplants. The findings […]