Entries by aaron

FDA Approves First Gene Therapy for rare genetic disease affecting brain and nervous system in kids

The U.S. Food and Drug Administration has approved first Gene Therapy for rare genetic disease affecting brain and nervous system in kids. Lenmeldy (atidarsagene autotemcel) is the first FDA-approved gene therapy indicated for the treatment of children with pre-symptomatic late infantile, pre-symptomatic early juvenile or early symptomatic early juvenile metachromatic leukodystrophy (MLD). Metachromatic leukodystrophy is […]

Dupilumab treatment may improve work productivity in patients with atopic dermatitis: Study

Japan: A recent study published in Experimental Dermatology has shed light on the impact of 1-year treatment with dupilumab on work productivity in Japanese patients with atopic dermatitis (AD). The researchers showed that Dupilumab improved work productivity in Japanese patients with atopic dermatitis. They stated that long-term remission of pruritus and improved quality of life […]

COVID-19 Vaccines Effectively Protect Individuals with Psychiatric Disorders: Study

A recent study published in the Influenza Other Respiratory Viruses journal examined the effectiveness of COVID-19 vaccines across various psychiatric disorders yielded promising outcomes. This study by Matthew Levy  and team from the VISION Network in four US determined if mental health conditions influence the efficacy of mRNA COVID-19 vaccines. The study encompassed data from a […]

Allogeneic stem cell therapy safe but fails to improve outcomes in acute ischemic stroke: JAMA

Japan: Findings from phase 2/3 TREASURE randomized clinical trial (RCT) that bone marrow-derived allogeneic stem cell therapy shortly after ischemic stroke was safe but failed to improve short-term outcomes. The findings were published online in JAMA Neurology on January 16, 2024. In the RCT with 206 participants, intravenous (IV) administration of intravenous allogeneic multipotent adult […]

Guidewire during TAVR procedures appears to be efficacious and safe: Study

In a recent study, the SavvyWire, a 0.035-inch pre-shaped guidewire with unique pacing properties and a distal pressure sensor, has demonstrated remarkable efficacy and safety during transcatheter aortic valve replacement (TAVR) procedures. The study, conducted across eight European centers, aimed to assess the device’s performance and safety in patients with severe aortic stenosis undergoing TAVR. […]

Rezafunginand caspofungin effective treatment option for invasive candidiasis

Rezafungin and caspofungin effective treatment options for invasive candidiasis suggest a new study published in the Lancet Infectious Diseases. Rezafungin, a new US Food and Drug Administration-approved, long-acting echinocandin to treat candidaemia and invasive candidiasis, was efficacious with a similar safety profile to caspofungin in clinical trials. We conducted pooled analyses of the phase 2 […]