Rezafungin and caspofungin effective treatment options for invasive candidiasis suggest a new study published in the Lancet Infectious Diseases. Rezafungin, a new US Food and Drug Administration-approved, long-acting echinocandin to treat candidaemia and invasive candidiasis, was efficacious with a similar safety profile to caspofungin in clinical trials. We conducted pooled analyses of the phase 2 […]
Germany: A recent study published in Diabetologia has shed light on survodutide dose-response effects on body weight and HbA1c reduction, compared with placebo and open-label semaglutide in patients with type 2 diabetes (T2D). Findings from the phase II randomized clinical trial showed a greater reduction in body weight and HbA1c levels after 16 weeks of […]
Short-term very low calorie diets are safe for teenagers living with moderate to severe obesity when closely monitored by an experienced dietitian, new research to be presented at the European Congress on Obesity (ECO 2024), has found. In addition, many of the adolescents who took part in the Australian study found a very low calorie […]
USA: A recent study published in Heart Rhythm has shown intravenous (IV) sotalol loading to be feasible and safe for atrial arrhythmias, and yield shorter hospitalization with low rates of adverse events. Antiarrhythmic drug therapy plays an important role in achieving rhythm control in atrial arrhythmias. In these patients, class III antiarrhythmic drugs are indicated […]
A new review of available evidence led by researchers at the Harvard Pilgrim Health Care Institute suggests that female reproductive characteristics may be overlooked as risk factors that contribute to later metabolic dysfunction. The review, “Reproductive risk factors across the female lifecourse and later metabolic health,” was published in the January 26 edition of Cell […]
Spain: A recent study published in Endocrinología, Diabetes y Nutrición has shed light on the risk factors associated with glomerular filtration rate (GFR) in Mexican adults with type 2 diabetes mellitus (T2DM). The researchers showed male sex, older age, longer duration of type 2 diabetes, and arterial hypertension were associated with a decrease in the […]
A recent study published in the Journal of American Medical Association investigated the potential of oral minocycline in slowing down the progression of geographic atrophy (GA) in age-related macular degeneration (AMD). GA is a leading cause of irreversible vision loss among the elderly which makes effective treatments crucial. Existing therapies for GA enlargement in AMD […]
A recent study published in the ACR Open Rheumatology journal explored the effectiveness of guselkumab in treating patients with psoriatic arthritis (PsA). The study evaluated patient-reported outcomes after 6 months of on-label guselkumab use and provided valuable insights into its real-world effectiveness. Psoriatic arthritis is a chronic inflammatory disease that affects the joints and skin that […]
USA: Consuming a high-fat diet can increase the risk of persistent postoperative cognitive dysfunction-associated memory impairments following surgery in a TLR4-dependent manner, a recent study published in Brain, Behavior, and Immunity has found. The study, building upon previous research from the same lab at Ohio State University, also showed that taking a DHA omega-3 fatty […]
Research led by Amsterdam UMC across ten Dutch hospitals and two Italian hospitals has found that not placing a drain during surgery improves outcomes in patients undergoing a left-sided pancreatic resection, also known as ‘distal pancreatectomy’. The study, today published in Lancet Gastroenterology & Hepatology, set out to confirm the safety of drainless surgery, as […]