Entries by aaron

Intravascular Imaging Increases Cost-Effectiveness of Coronary Artery Procedures: AHA

A recent study unveiled the cost-effectiveness of intravascular imaging-guided percutaneous coronary intervention (PCI) compared to conventional angiography-guided procedures. The findings were published in Circulation: Cardiovascular Quality and Outcomes reveal significant benefits for patients with complex coronary artery lesions. The RENOVATE-COMPLEX-PCI trial was conducted in Korea from May 2018 to May 2021 and examined the clinical […]

Invasive Angiography Adds Nothing to CCTA Alone for risk stratification of patients with stable CAD: ISCHEMIA

Canada: An analysis of the ISCHEMIA trial revealed that both invasive coronary angiography and coronary CT angiography (CCTA) add incremental information over baseline characteristics for predicting risk in stable coronary artery disease (CAD) patients. The findings, published in JACC: Cardiovascular Imaging, also show that invasive angiography addition on top of CCTA does not provide any […]

Switching to integrase inhibitor may accelerate weight gain during menopause inHIV patients: Study

Integrase strand transfer inhibitors (INSTIs) are associated with more significant weight gain in women with HIV (WWH) compared to men with HIV. Menopausal transition leads to changes in body composition. A finding published in CROI, Conference on Retroviruses and Opportunistic Infections, mentioned that switching to INSTIs during the late peri- and postmenopausal phase is associated […]

No advatage of Laparoscopic surgery over open surgery in reducing risk of bowel obstruction in complicated appendicitis: Study

No advantage of Laparoscopic surgery over open surgery in reducing the risk of bowel obstruction in complicated appendicitis suggests a new study published in the Journal of Pediatric Surgery. Complicated appendicitis is associated with a higher risk of postoperative complications, including adhesive bowel obstruction. This meta-analysis aims to investigate the difference in rates of postoperative […]

Buteyko breathing technique effective adjunct in asthma therapy deserving wider attention, suggests study

It has been suggested that non-pharmaceutical approaches, such as the Buteyko breathing technique (BBT), be implemented to support traditional asthma therapy. However, the evidence regarding their effectiveness needs to be more consistent. A European Journal of Medical Research study has concluded that BBT is clinically effective. Despite the significant reduction of respiratory pharmacotherapy, improved symptom […]

Febuxostat significantly benefits renal function-related indices in gout patients: Study

Two commonly prescribed medications for gout treatment are febuxostat and benzbromarone. However, their clinical efficacy remains a subject of debate. A European Review for Medical and Pharmacological Sciences study concluded that Febuxostat significantly benefits renal function-related indexes, including the estimated glomerular filtration rate (eGFR), Cr, and blood urea nitrogen (BUN). In contrast, benzbromarone is more […]

Children with atopic dermatitis experience hindered growth compared to peers: PEDISTAD trial

USA: Recent data from the PEDISTAD study showed a negative impact of moderate-to-severe atopic dermatitis (AD) on growth in children aged <12 years, potentially due to sleep deprivation to long-term exposure to systemic or topical glucocorticoids and immunosuppressants. The study showed that children with eczema have a lower mean height and higher mean weight and […]

Krackow sutures combined with vertical Nice stable and reliable in treatment of inferior patellar fractures: study

Xinhui Du et al used a new surgical technique of Krackow suture combined with vertical Nice knot for the treatment of inferior patellar fractures and reported the clinical results. The study was published in ‘Indian Journal of Orthopaedics.’ Seventeen consecutive patients admitted with inferior patellar fractures were prospectively enrolled. The AO classification was 34-A1. All […]